(Q43465454)

23 November 2017

title

Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers (English)

1 reference

23 November 2017

Laetitia Seguin

1

1 reference

23 November 2017

Maria F Camargo

2

1 reference

23 November 2017

Hiromi I Wettersten

3

1 reference

23 November 2017

Shumei Kato

4

1 reference

23 November 2017

Jay S Desgrosellier

5

1 reference

23 November 2017

Tami von Schalscha

6

1 reference

23 November 2017

Kathryn C Elliott

7

1 reference

23 November 2017

Erika Cosset

8

1 reference

23 November 2017

Jacqueline Lesperance

9

1 reference

23 November 2017

Sara M Weis

10

1 reference

23 November 2017

David A Cheresh

11

1 reference

23 November 2017

publication date

11 September 2017

1 reference

23 November 2017

1 reference

describes a project that uses

23 November 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5718959/fullTextXML

inferred from PubMed Central ID database lookup

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The relevance of using 3D cell cultures, in addition to 2D monolayer cultures, when evaluating breast cancer drug sensitivity and resistance

27 August 2018

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Galectin-3 Determines Tumor Cell Adaptive Strategies in Stressed Tumor Microenvironments

27 August 2018

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Reductive carboxylation supports redox homeostasis during anchorage-independent growth

27 August 2018

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KRAS-Mutant Lung Cancers in the Era of Targeted Therapy

27 August 2018

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Galectin 3 as a guardian of the tumor microenvironment

27 August 2018

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27 August 2018

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27 August 2018

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27 August 2018

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27 August 2018

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Drugging the undruggable RAS: Mission possible?

27 August 2018

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27 August 2018

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Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer

27 August 2018

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An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.

27 August 2018

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Determining the macropinocytic index of cells through a quantitative image-based assay

27 August 2018

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Oncogenic K-ras segregates at spatially distinct plasma membrane signaling platforms according to its phosphorylation status

27 August 2018

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Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

27 August 2018

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αv-Integrin isoform expression in primary human tumors and brain metastases

27 August 2018

1 reference

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Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer

27 August 2018

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Galectin-3 mediates cross-talk between K-Ras and Let-7c tumor suppressor microRNA

27 August 2018

1 reference

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RAS oncogenes: weaving a tumorigenic web

27 August 2018

1 reference

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Galectin-3--a jack-of-all-trades in cancer

27 August 2018

1 reference

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Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

27 August 2018

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Macropinocytosis: an endocytic pathway for internalising large gulps

27 August 2018

1 reference

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Multiple cellular proteins modulate the dynamics of K-ras association with the plasma membrane

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718959

Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718959

Galectin-3 Promotes Chronic Activation of K-Ras and Differentiation Block in Malignant Thyroid Carcinomas

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718959

A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors.

27 August 2018

1 reference

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Signalling ballet in space and time

27 August 2018

1 reference

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GCS-100, a novel galectin-3 antagonist, modulates MCL-1, NOXA, and cell cycle to induce myeloma cell death

27 August 2018

1 reference

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Proliferative and nonproliferative lesions of the rat and mouse respiratory tract.

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718959

Integrins in cancer: biological implications and therapeutic opportunities

27 August 2018

1 reference

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An integrin alpha(v)beta(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression

27 August 2018

1 reference

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Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase

27 August 2018

1 reference

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Anchorage-independent cell growth signature identifies tumors with metastatic potential

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718959

A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718959

K-ras nanoclustering is subverted by overexpression of the scaffold protein galectin-3.

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718959

Pharmacological inhibition of endocytic pathways: is it specific enough to be useful?

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718959

Simple quantitative detection of mitochondrial superoxide production in live cells

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718959

Galectin-3 regulates a molecular switch from N-Ras to K-Ras usage in human breast carcinoma cells

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718959

Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718959

Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortium

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718959

Modeling tissue-specific signaling and organ function in three dimensions

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718959

27 August 2018

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718959

Inhibition of Human Cancer Cell Growth and Metastasis in Nude Mice by Oral Intake of Modified Citrus Pectin

27 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28893801

12 December 2020

inferred from PubMed ID database lookup

BRAF and RAS mutations in human lung cancer and melanoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28893801

12 December 2020

inferred from PubMed ID database lookup

Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28893801

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1158/2159-8290.CD-17-0539

1 reference

23 November 2017

0 references

1 reference