(Q43500128)

24 November 2017

Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors (English)

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24 November 2017

7

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24 November 2017

8

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24 November 2017

Brian Lohse

1

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Jesper L. Kristensen

object named as

Jesper L Kristensen

9

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author name string

Anders L Nielsen

2

1 reference

24 November 2017

Jan B L Kristensen

3

1 reference

24 November 2017

Charlotte Helgstrand

4

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24 November 2017

Paul A C Cloos

5

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24 November 2017

Lars Olsen

6

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24 November 2017

language of work or name

English

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publication date

25 August 2011

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Angewandte Chemie International Edition

24 November 2017

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volume

50

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24 November 2017

39

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24 November 2017

9100-9103

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Chromatin modifications and their function

24 November 2017

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

Translating the Histone Code

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

Chromatin modification and epigenetic reprogramming in mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

JmjC-domain-containing proteins and histone demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

Oncogene-induced senescence as an initial barrier in lymphoma development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

Comprehensive genomic analysis of desmoplastic medulloblastomas: identification of novel amplified genes and separate evaluation of the different histological components

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia, and is a key mediator of estrogen induced growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

Mutations in PHF8 are associated with X linked mental retardation and cleft lip/cleft palate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

Inhibitors of histone demethylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

Syntheses and therapeutic potential of hydroxamic acid based siderophores and analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

Comparative analysis of small molecules and histone substrate analogues as LSD1 lysine demethylase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

A miniaturized screen for inhibitors of Jumonji histone demethylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

A mechanism-based inactivator for histone demethylase LSD1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

A selective inhibitor and probe of the cellular functions of Jumonji C domain-containing histone demethylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201101849

21 January 2018

Identifiers

DOI

10.1002/ANIE.201101849

1 reference

24 November 2017

1 reference