(Q43559468)

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A regulatory hydrophobic area in the flexible joint region of plasminogen activator inhibitor-1, defined with fluorescent activity-neutralizing ligands. Ligand-induced serpin polymerization

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1 reference

Europe PubMed Central

24 November 2017

A regulatory hydrophobic area in the flexible joint region of plasminogen activator inhibitor-1, defined with fluorescent activity-neutralizing ligands. Ligand-induced serpin polymerization (English)

1 reference

Europe PubMed Central

24 November 2017

1 reference

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author name string

R Egelund

1

1 reference

Europe PubMed Central

24 November 2017

A P Einholm

2

1 reference

Europe PubMed Central

24 November 2017

K E Pedersen

3

1 reference

Europe PubMed Central

24 November 2017

R W Nielsen

4

1 reference

Europe PubMed Central

24 November 2017

A Christensen

5

1 reference

Europe PubMed Central

24 November 2017

J Deinum

6

1 reference

Europe PubMed Central

24 November 2017

P A Andreasen

7

1 reference

Europe PubMed Central

24 November 2017

language of work or name

0 references

publication date

25 January 2001

1 reference

Europe PubMed Central

24 November 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

24 November 2017

276

1 reference

Europe PubMed Central

24 November 2017

16

1 reference

Europe PubMed Central

24 November 2017

13077-13086

1 reference

Europe PubMed Central

24 November 2017

Plasminogen activator inhibitors: hormonally regulated serpins

1 reference

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21 January 2018

Role of vitronectin and its receptors in haemostasis and vascular remodeling

1 reference

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21 January 2018

The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?

1 reference

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Plasminogen activator inhibitor-1 represses integrin- and vitronectin-mediated cell migration independently of its function as an inhibitor of plasminogen activation

1 reference

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21 January 2018

The urokinase-type plasminogen activator system in cancer metastasis: a review

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21 January 2018

The plasminogen activation system in tumor growth, invasion, and metastasis

1 reference

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21 January 2018

Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Structural basis for serpin inhibitor activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

The biostructural pathology of the serpins: critical function of sheet opening mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

A fluorescent probe study of plasminogen activator inhibitor-1. Evidence for reactive center loop insertion and its role in the inhibitory mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

The inhibition mechanism of serpins. Evidence that the mobile reactive center loop is cleaved in the native protease-inhibitor complex.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Major proteinase movement upon stable serpin-proteinase complex formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Mapping the serpin-proteinase complex using single cysteine variants of alpha1-proteinase inhibitor Pittsburgh.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Formation of the covalent serpin-proteinase complex involves translocation of the proteinase by more than 70 A and full insertion of the reactive center loop into beta-sheet A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

An ester bond linking a fragment of a serine proteinase to its serpin inhibitor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Structure of a serpin-protease complex shows inhibition by deformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Structural basis of latency in plasminogen activator inhibitor-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Serpin tertiary structure transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Mechanisms contributing to the conformational and functional flexibility of plasminogen activator inhibitor-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

The active conformation of plasminogen activator inhibitor 1, a target for drugs to control fibrinolysis and cell adhesion

1 reference

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21 January 2018

Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Peptide-mediated inactivation of recombinant and platelet plasminogen activator inhibitor-1 in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

The acid stabilization of plasminogen activator inhibitor-1 depends on protonation of a single group that affects loop insertion into beta-sheet A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Interfering with the inhibitory mechanism of serpins: crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Selection of peptides that bind to plasminogen activator inhibitor 1 (PAI-1) using random peptide phage-display libraries

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

A substrate-like form of plasminogen-activator-inhibitor type 1. Conversions between different forms by sodium dodecyl sulphate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Interconversions between active, inert and substrate forms of denatured/refolded type-1 plasminogen activator inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Identification of the binding site for a low-molecular-weight inhibitor of plasminogen activator inhibitor type 1 by site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Purification and characterization of active and stable recombinant plasminogen-activator inhibitor accumulated at high levels in Escherichia coli.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

A serpin-induced extensive proteolytic susceptibility of urokinase-type plasminogen activator implicates distortion of the proteinase substrate-binding pocket and oxyanion hole in the serpin inhibitory mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Properties of detergents

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Wild-type alpha 1-antitrypsin is in the canonical inhibitory conformation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Topography of a 2.0 Å structure of α1-antitrypsin reveals targets for rational drug design to prevent conformational disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Molecular basis of agonism and antagonism in the oestrogen receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

1 reference

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21 January 2018

Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist

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https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Biological implications of a 3 A structure of dimeric antithrombin

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21 January 2018

The anticoagulant activation of antithrombin by heparin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

The intact and cleaved human antithrombin III complex as a model for serpin-proteinase interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Polymerization of plasminogen activator inhibitor-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

The urokinase receptor is a major vitronectin-binding protein on endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Melanoma cell migration on vitronectin: regulation by components of the plasminogen activation system

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21 January 2018

The role of plasminogen activator inhibitor-1 as inhibitor of platelet and megakaryoblastic cell adhesion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Serpin-protease complexes are trapped as stable acyl-enzyme intermediates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Structural insights into serpin-protease complexes reveal the inhibitory mechanism of serpins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

The structure of a serpin-protease complex revealed by intramolecular distance measurements using donor-donor energy migration and mapping of interaction sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Type-1 plasminogen-activator inhibitor -- conformational differences between latent, active, reactive-centre-cleaved and plasminogen-activator-complexed forms, as probed by proteolytic susceptibility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Determination of the vitronectin binding site on plasminogen activator inhibitor 1 (PAI‐1)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Binding of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex to the endocytosis receptors alpha2-macroglobulin receptor/low-density lipoprotein receptor-related protein and very-low-density lipoprotein receptor involves

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009024200

21 January 2018

Ligand interaction between urokinase-type plasminogen activator and its receptor probed with 8-anilino-1-naphthalenesulfonate. Evidence for a hydrophobic binding site exposed only on the intact receptor

1 reference

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21 January 2018

The interaction of a naphthalene dye with apomyoglobin and apohemoglobin. A fluorescent probe of non-polar binding sites

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21 January 2018

Dimer formation from 1-amino-8-naphthalenesulfonate catalyzed by bovine serum albumin. A new fluorescent molecule with exceptional binding properties

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21 January 2018

A fluorimetric method for the estimation of the critical micelle concentration of surfactants

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Identifiers

10.1074/JBC.M009024200

1 reference

Europe PubMed Central

24 November 2017

1 reference

Europe PubMed Central

24 November 2017

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