(Q43689383)

English

Microsomal prostaglandin E synthase-1 is induced in alzheimer's disease and its deletion mitigates alzheimer's disease-like pathology in a mouse model

scientific article published on 29 March 2013

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scholarly article

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Europe PubMed Central

PubMed publication ID

25 November 2017

Microsomal prostaglandin E synthase-1 is induced in alzheimer's disease and its deletion mitigates alzheimer's disease-like pathology in a mouse model (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

Alzheimer's disease

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prostaglandin E2

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based on heuristic

inferred from title

Masato Hosokawa

object named as

Masato Hosokawa

4

0 references

Satoshi Uematsu

6

object named as

Satoshi Uematsu

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

author name string

Yoshiharu Akitake

1

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Europe PubMed Central

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25 November 2017

Yoshihito Nakatani

2

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Europe PubMed Central

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25 November 2017

Daisuke Kamei

3

1 reference

Europe PubMed Central

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25 November 2017

Hiroyasu Akatsu

5

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

Shizuo Akira

7

1 reference

Europe PubMed Central

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25 November 2017

Ichiro Kudo

8

1 reference

Europe PubMed Central

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25 November 2017

Shuntaro Hara

9

1 reference

Europe PubMed Central

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25 November 2017

Mitsuo Takahashi

10

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25 November 2017

publication date

29 March 2013

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25 November 2017

Journal of Neuroscience Research

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Europe PubMed Central

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25 November 2017

91

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25 November 2017

7

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25 November 2017

909-919

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25 November 2017

Inflammation and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Cytosolic prostaglandin E synthase: expression patterns in control and Alzheimer's disease brains

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Elevated microsomal prostaglandin-E synthase-1 in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Microsomal prostaglandin E synthase-2: cellular distribution and expression in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Mechanisms of microglia accumulation in Alzheimer's disease: therapeutic implications

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Altered expression of COX-2 in subdivisions of the hippocampus during aging and in Alzheimer's disease: the Hisayama Study.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Prostaglandin E synthases: Understanding their pathophysiological roles through mouse genetic models

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Involvement of prostaglandin E2 in production of amyloid-beta peptides both in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Improvement of cognitive function in Alzheimer's disease model mice by genetic and pharmacological inhibition of the EP(4) receptor.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Microsomal prostaglandin E synthase-1 contributes to ischaemic excitotoxicity through prostaglandin E2 EP3 receptors.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Reduced pain hypersensitivity and inflammation in mice lacking microsomal prostaglandin e synthase-1.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Targeted lipidomics reveals mPGES-1-PGE2 as a therapeutic target for multiple sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Deletion of microsomal prostaglandin E synthase-1 protects neuronal cells from cytotoxic effects of β-amyloid peptide fragment 31-35.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Deletion of the prostaglandin E2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

NSAIDs and Alzheimer disease: epidemiological, animal model and clinical studies

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

A fibril-specific, conformation-dependent antibody recognizes a subset of Abeta plaques in Alzheimer disease, Down syndrome and Tg2576 transgenic mouse brain

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Expression of prostaglandin E synthase mRNA is induced in beta-amyloid treated rat astrocytes

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Microglia lacking E Prostanoid Receptor subtype 2 have enhanced Abeta phagocytosis yet lack Abeta-activated neurotoxicity

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Interactions of PGH synthase isozymes-1 and -2 with NSAIDs

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Novel therapeutic opportunities for Alzheimer's disease: focus on nonsteroidal anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1002%2FJNR.23217

21 January 2018

Identifiers

10.1002/JNR.23217

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

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