(Q43722192)

English

Metabolic activation of carcinogenic 1-nitropyrene by human cytochrome P450 1B1 in Salmonella typhimurium strain expressing an O-acetyltransferase in SOS/umu assay

scientific article published in October 2001

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Metabolic activation of carcinogenic 1-nitropyrene by human cytochrome P450 1B1 in Salmonella typhimurium strain expressing an O-acetyltransferase in SOS/umu assay (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Salmonella Typhimurium

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based on heuristic

inferred from title

Hiroshi Yamazaki

2

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

F. Peter Guengerich

4

object named as

F P Guengerich

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Europe PubMed Central

PubMed publication ID

26 November 2017

author name string

N Hatanaka

1

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Europe PubMed Central

PubMed publication ID

26 November 2017

Y Oda

3

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

M Nakajima

5

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

T Yokoi

6

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

language of work or name

0 references

publication date

1 October 2001

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Mutation Research

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Europe PubMed Central

PubMed publication ID

26 November 2017

497

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Europe PubMed Central

PubMed publication ID

26 November 2017

1-2

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Europe PubMed Central

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26 November 2017

223-233

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Europe PubMed Central

PubMed publication ID

26 November 2017

Mutagenicity and genotoxicity of nitroarenes. All nitro-containing chemicals were not created equal

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Nitrated polycyclic aromatic hydrocarbons: a risk assessment for the urban citizen

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1-Nitropyrene as a marker for the mutagenicity of diesel exhaust-derived particulate matter in workplace atmospheres.

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In vivo metabolism and genotoxic effects of nitrated polycyclic aromatic hydrocarbons

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The metabolism of 1-nitropyrene by human cytochromes P450.

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Aerobic and anaerobic reduction of nitrated pyrenes in vitro.

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Bioactivation of diesel exhaust particle extracts and their major nitrated polycyclic aromatic hydrocarbon components, 1-nitropyrene and dinitropyrenes, by human cytochromes P450 1A1, 1A2, and 1B1.

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Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes

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P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

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Metabolism of chemical carcinogens

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Chemical carcinogenesis

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Comparison of three different in vitro mutation assays used for the investigation of cytochrome P450-mediated mutagenicity of nitro-polycyclic aromatic hydrocarbons

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Synthesis and mutagenicity of 1-nitropyrene 4,5-oxide and 1-nitropyrene 9,10-oxide, microsomal metabolites of 1-nitropyrene

1 reference

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Role of nitroreductases but not cytochromes P450 in the metabolic activation of 1-nitropyrene in the HepG2 human hepatoblastoma cell line

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The induction of DNA adducts in mammalian cells exposed to 1-nitropyrene and its nitro-reduced derivatives

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Metabolic activation of 1-nitropyrene to a mammalian cell mutagen and a carcinogen

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Induction of rat hepatic cytochromes P-450 by environmental nitropolycyclic aromatic hydrocarbons

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Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity

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Targets for dioxin: genes for plasminogen activator inhibitor-2 and interleukin-1 beta

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Roles of cytochromes P450 1A2 and 3A4 in the oxidation of estradiol and estrone in human liver microsomes

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7 January 2021

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Evaluation of the new system (umu-test) for the detection of environmental mutagens and carcinogens

1 reference

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A sensitive umu test system for the detection of mutagenic nitroarenes in Salmonella typhimurium NM1011 having a high nitroreductase activity.

1 reference

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7 January 2021

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Drug metabolism by Escherichia coli expressing human cytochromes P450.

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Roles of NADPH-P450 reductase in the O-deethylation of 7-ethoxycoumarin by recombinant human cytochrome P450 1B1 variants in Escherichia coli.

1 reference

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7 January 2021

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Distributions of nitropyrenes and mutagenicity in airborne particulates collected with an Andersen sampler.

1 reference

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7 January 2021

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Assessment of occupational exposure to diesel exhaust. The use of an immunoassay for the determination of urinary metabolites of nitroarenes and polycyclic aromatic hydrocarbons

1 reference

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Excretion and metabolism of 1-nitropyrene in rats after oral or intraperitoneal administration

1 reference

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Polycyclic nitroarenes (nitro-PAHs) as biomarkers of exposure to diesel exhaust

1 reference

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N-and O-acetylation of aromatic and heterocyclic amine carcinogens by human monomorphic and polymorphic acetyltransferases expressed in COS-1 cells

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Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals

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Highly sensitive umu test system for the detection of mutagenic nitroarenes in Salmonella typhimurium NM3009 having high O-acetyltransferase and nitroreductase activities.

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7 January 2021

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inferred from DOI database lookup

Identifiers

10.1016/S1383-5718(01)00254-6

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

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