(Q43741180)

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Different dynamic movements of wild-type and pathogenic VCPs and their cofactors to damaged mitochondria in a Parkin-mediated mitochondrial quality control system.

scientific article published on 12 November 2013

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29 February 2020

Different dynamic movements of wild-type and pathogenic VCPs and their cofactors to damaged mitochondria in a Parkin-mediated mitochondrial quality control system (English)

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29 February 2020

quality control

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Noriyuki Matsuda

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29 February 2020

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Yoko Kimura

1

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29 February 2020

Junpei Fukushi

2

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29 February 2020

Seiji Hori

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29 February 2020

Kei Okatsu

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29 February 2020

Yukie Kakiyama

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29 February 2020

Junko Kawawaki

7

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29 February 2020

Akira Kakizuka

8

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29 February 2020

Keiji Tanaka

9

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29 February 2020

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12 November 2013

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29 February 2020

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29 February 2020

18

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29 February 2020

12

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29 February 2020

1131-1143

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29 February 2020

Pathogenic VCP mutations induce mitochondrial uncoupling and reduced ATP levels

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Crucial mitochondrial impairment upon CDC48 mutation in apoptotic yeast.

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Valosin-containing protein mutation and Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

A unique IBMPFD-related P97/VCP mutation with differential binding pattern and subcellular localization

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Imbalances in p97 co-factor interactions in human proteinopathy

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformation

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

A stress-responsive system for mitochondrial protein degradation

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Identification of ter94, Drosophila VCP, as a modulator of polyglutamine-induced neurodegeneration

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

VCP/p97 in abnormal protein aggregates, cytoplasmic vacuoles, and cell death, phenotypes relevant to neurodegeneration

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

The ubiquitin-selective chaperone CDC-48/p97 links myosin assembly to human myopathy

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Cdc48 (p97): a "molecular gearbox" in the ubiquitin pathway?

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

The mitochondrial inner membrane protein mitofilin controls cristae morphology

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Exome sequencing reveals VCP mutations as a cause of familial ALS

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Impaired protein aggregate handling and clearance underlie the pathogenesis of p97/VCP-associated disease

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Polyglutamine diseases and molecular chaperones

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

p47 is a cofactor for p97-mediated membrane fusion

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Cdc48/p97 and Shp1/p47 regulate autophagosome biogenesis in concert with ubiquitin-like Atg8

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

The homozygote VCP(R¹⁵⁵H/R¹⁵⁵H) mouse model exhibits accelerated human VCP-associated disease pathology

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

ATPase activity of p97/valosin-containing protein is regulated by oxidative modification of the evolutionally conserved cysteine 522 residue in Walker A motif

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97.

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Degenerative changes in the mitochondria of flight muscle from aging blowflies

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

p47 negatively regulates IKK activation by inducing the lysosomal degradation of polyubiquitinated NEMO.

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Cdc48: a power machine in protein degradation

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Rescue of growth defects of yeast cdc48 mutants by pathogenic IBMPFD-VCPs.

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

A novel ATP-dependent conformation in p97 N–D1 fragment revealed by crystal structures of disease-related mutants

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Mitochondrial "swirls" induced by oxygen stress and in the Drosophila mutant hyperswirl

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Slow development of ALS-like spinal cord pathology in mutant valosin-containing protein gene knock-in mice

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

1 reference

https://api.crossref.org/works/10.1111%2FGTC.12103

21 January 2018

Identifiers

10.1111/GTC.12103

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24215292%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24215292%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

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