(Q43754354)

26 November 2017

Relative contribution of CYP3A to amitriptyline clearance in humans: in vitro and in vivo studies (English)

1 reference

26 November 2017

1 reference

3

Harmatz JS

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26 November 2017

11

Greenblatt DJ

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26 November 2017

10

Shader RI

1 reference

26 November 2017

5

von Moltke LL

1 reference

26 November 2017

Venkatakrishnan K

1

1 reference

26 November 2017

Schmider J

2

1 reference

26 November 2017

Ehrenberg BL

4

1 reference

26 November 2017

Graf JA

6

1 reference

26 November 2017

Mertzanis P

7

1 reference

26 November 2017

Corbett KE

8

1 reference

26 November 2017

Rodriguez MC

9

1 reference

26 November 2017

language of work or name

1 reference

1 October 2001

1 reference

The Journal of Clinical Pharmacology

26 November 2017

1 reference

26 November 2017

41

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26 November 2017

1043-1054

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26 November 2017

10

1 reference

Urinary metabolites of amitriptylinoxide and amitriptyline in single-dose experiments and during continuous therapy

26 November 2017

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Enzyme kinetic modelling as a tool to analyse the behaviour of cytochrome P450 catalysed reactions: application to amitriptyline N-demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Cytochrome P-450 3A4: regulation and role in drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Cooperativity in oxidations catalyzed by cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Reconstitution premixes for assays using purified recombinant human cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

The use of heterologously expressed drug metabolizing enzymes--state of the art and prospects for the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Distinguishing a benzodiazepine agonist (triazolam) from a nonagonist anxiolytic (buspirone) by electroencephalography: kinetic-dynamic studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Pharmacokinetics and pharmacodynamics of diphenhydramine 25 mg in young and elderly volunteers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Sedative effects and impaired learning and recall after single oral doses of lorazepam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

GC and GC-MS procedures for simultaneous phenotyping with dextromethorphan and mephenytoin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Discrepancies between pharmacokinetic studies of amitriptyline.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Effects of the antifungal agents on oxidative drug metabolism: clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Effect of ketoconazole and terbinafine on the pharmacokinetics of caffeine in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

The effect of fluconazole and ketoconazole on the metabolism of sulphamethoxazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Contrasting effects of fluconazole and ketoconazole on phenytoin and testosterone disposition in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Disposition of ketoconazole, an oral antifungal, in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Inhibition of the sulfoxidation of omeprazole by ketoconazole in poor and extensive metabolizers of S-mephenytoin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Effect of ketoconazole on the pharmacokinetics of imipramine and desipramine in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Zolpidem metabolism in vitro: responsible cytochromes, chemical inhibitors, and in vivo correlations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Pharmacokinetic-pharmacodynamic relationships for benzodiazepines

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Pre-stimulus/post-stimulus relations in EEG spectra and their modulations by an opioid and an antidepressant

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Quantitative pharmaco-electroencephalographic differentiation between the CNS effects of bromocriptine and imipramine, drugs with qualitatively different antidepressant properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

CYP2D6- and CYP3A-dependent metabolism of dextromethorphan in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Amitriptyline metabolism: relationship to polymorphic debrisoquine hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Amitriptyline metabolism: association with debrisoquin hydroxylation in nonsmokers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Interindividual differences in amitriptyline demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Enantioselective amitriptyline metabolism in patients phenotyped for two cytochrome P450 isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Biotransformation of amitriptyline in depressive patients: urinary excretion of seven metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Five distinct human cytochromes mediate amitriptyline N-demethylation in vitro: dominance of CYP 2C19 and 3A4

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Metabolism of the Tricyclic Antidepressant Amitriptyline by cDNA-Expressed Human Cytochrome P450 Enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Metabolism of drugs by cytochrome P450 3A isoforms. Implications for drug interactions in psychopharmacology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Use of cDNA-expressed human cytochrome P450 enzymes to study potential drug-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Ketoconazole inhibition of triazolam and alprazolam clearance: differential kinetic and dynamic consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Kinetic and dynamic interaction study of zolpidem with ketoconazole, itraconazole, and fluconazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

In vivo and in vitro measurement of CYP2C19 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Tricyclic antidepressant determination in human plasma by gas-liquid chromatography using nitrogen-phosphorous detection: application to single-dose pharmacokinetic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

The effect of ketoconazole on the pharmacokinetics, pharmacodynamics and safety of nisoldipine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Effect of ketoconazole on hepatic oxidative drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Effect of chronically administered ketoconazole on the elimination of theophylline in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Predicting drug interactions in vivo from experiments in vitro. Human studies with paclitaxel and ketoconazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Determination of ketoconazole in the plasma, liver, lung and adrenal of the rat by high-performance liquid chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Disposition of azole antifungal agents. I. Nonlinearities in ketoconazole clearance and binding in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

Electrophysiologic analysis of antidepressant drug effects on the GABA(A) receptor complex based upon antagonist-induced encephalographic power spectrum changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122012634

10.1177/00912700122012634

21 January 2018

Identifiers

DOI

1 reference

26 November 2017

1 reference