(Q43842810)

27 November 2017

title

A trans-acting ketoreductase in biosynthesis of a symmetric polyketide dimer SIA7248. (English)

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27 November 2017

4

Zixin Deng

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27 November 2017

Yi Zou

1

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27 November 2017

Haixing Yin

series ordinal

2

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27 November 2017

Dekun Kong

series ordinal

3

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27 November 2017

Shuangjun Lin

series ordinal

5

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27 November 2017

publication date

15 March 2013

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27 November 2017

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27 November 2017

volume

14

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27 November 2017

issue

6

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27 November 2017

page(s)

679-683

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Natural products as sources of new drugs over the 30 years from 1981 to 2010

27 November 2017

cites work

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The structures of type I polyketide synthases

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Short-chain dehydrogenases/reductases (SDR): the 2002 update

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Stereospecificity of ketoreductase domains of the 6-deoxyerythronolide B synthase

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A tylosin ketoreductase reveals how chirality is determined in polyketides

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Stereospecificity of ketoreductase domains 1 and 2 of the tylactone modular polyketide synthase

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The biochemical basis for stereochemical control in polyketide biosynthesis

21 January 2018

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Conserved amino acid residues correlating with ketoreductase stereospecificity in modular polyketide synthases

21 January 2018

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A model of structure and catalysis for ketoreductase domains in modular polyketide synthases

21 January 2018

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A fungal ketoreductase domain that displays substrate-dependent stereospecificity

21 January 2018

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Broad substrate specificity of ketoreductases derived from modular polyketide synthases.

21 January 2018

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Ketoreduction in mycolactone biosynthesis: insight into substrate specificity and stereocontrol from studies of discrete ketoreductase domains in vitro

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Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification

21 January 2018

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Isoprenoid-like alkylations in polyketide biosynthesis

21 January 2018

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Cloning and elucidation of the FR901464 gene cluster revealing a complex acyltransferase-less polyketide synthase using glycerate as starter units.

21 January 2018

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Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations.

21 January 2018

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Polyketide proofreading by an acyltransferase-like enzyme

21 January 2018

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Structure of beta-ketoacyl-[acyl carrier protein] reductase from Escherichia coli: negative cooperativity and its structural basis

21 January 2018

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Elucidation of Piericidin A1 biosynthetic locus revealed a thioesterase-dependent mechanism of α-pyridone ring formation

21 January 2018

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Regiospecific chlorination of (S)-beta-tyrosyl-S-carrier protein catalyzed by SgcC3 in the biosynthesis of the enediyne antitumor antibiotic C-1027

21 January 2018

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Tailoring enzymes acting on carrier protein-tethered substrates in natural product biosynthesis.

21 January 2018

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Marinomycins A-D, antitumor-antibiotics of a new structure class from a marine actinomycete of the recently discovered genus "marinispora".

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/CBIC.201300068

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27 November 2017

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