(Q43898845)

English

Species differences in the metabolism of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid in vitro: implications for prediction of metabolic interactions in vivo

scientific article published in February 2002

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

27 November 2017

Species differences in the metabolism of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid in vitro: implications for prediction of metabolic interactions in vivo (English)

1 reference

Europe PubMed Central

27 November 2017

Malcolm D. Tingle

2

1 reference

Europe PubMed Central

27 November 2017

James W. Paxton

4

1 reference

Europe PubMed Central

27 November 2017

author name string

Zhou SF

1

1 reference

Europe PubMed Central

27 November 2017

Kestell P

3

1 reference

Europe PubMed Central

27 November 2017

language of work or name

0 references

publication date

1 February 2002

1 reference

Europe PubMed Central

27 November 2017

1 reference

Europe PubMed Central

27 November 2017

32

1 reference

Europe PubMed Central

27 November 2017

2

1 reference

Europe PubMed Central

27 November 2017

87-107

1 reference

Europe PubMed Central

27 November 2017

Interspecies variation in liver weight, hepatic blood flow, and antipyrine intrinsic clearance: Extrapolation of data to benzodiazepines and phenytoin

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Interspecies scaling, allometry, physiological time, and the ground plan of pharmacokinetics.

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Glucuronidation of diflunisal in liver and kidney microsomes of rat and man.

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Microsomal prediction of in vivo clearance of CYP2C9 substrates in humans

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Effect of thalidomide on tumour necrosis factor production and anti-tumour activity induced by 5,6-dimethylxanthenone-4-acetic acid

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Metabolism of Arylacetic Acids: 1. The Fate of 1-Naphthylacetic Acid and its Variation with Species and Dose

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Studies on the metabolism of arylacetic acids. 6. Comparative metabolic conjugation of 1- and 2-naphthylacetic acids in the guinea pig, mouse, hamster and gerbil

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

The metabolism of xenobiotics by certain extrahepatic organs and its relation to toxicity

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Selective inhibitors of cytochromes P450.

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Quantitative prediction of in vivo drug clearance and drug interactions from in vitro data on metabolism, together with binding and transport

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Extrahepatic metabolism of drugs in humans

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Enhancement of the anti-tumour effects of the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) by combination with 5-hydroxytryptamine and bioreductive drugs

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Cytochromes P450 and species differences in xenobiotic metabolism and activation of carcinogen

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Allometric issues in drug development

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Dosage regimen design for pharmaceutical studies conducted in animals.

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

P450 in the rat and man: methods of investigation, substrate specificities and relevance to cancer

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

The allometric approach for interspecies scaling of pharmacokinetics and toxicity of anti-cancer drugs

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Potential antitumor agents. 58. Synthesis and structure-activity relationships of substituted xanthenone-4-acetic acids active against the colon 38 tumor in vivo

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

A dispersion model of hepatic elimination: 1. Formulation of the model and bolus considerations.

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Clearance concepts in pharmacokinetics

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man.

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Measurement of protein using bicinchoninic acid

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Bosentan, a new endothelin receptor antagonist: prediction of the systemic plasma clearance in man from combined in vivo and in vitro data

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Commentary: a physiological approach to hepatic drug clearance

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Drugs and the liver. Part III: Ageing of the liver and the metabolism of drugs

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Effects of the serotonin receptor antagonist cyproheptadine on the activity and pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid (DMXAA).

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

In vitro and in vivo kinetic interactions of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid with thalidomide and diclofenac

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Reversible binding of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid to plasma proteins and its distribution into blood cells in various species

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

The structure and function of the UDP-glucuronosyltransferase gene family

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

The effect of various potential inhibitors, activators and inducers on theN-oxidation of 3-substituted pyridinesin vitro

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Plasma disposition, metabolism and excretion of the experimental antitumour agent 5,6-dimethylxanthenone-4-acetic acid in the mouse, rat and rabbit

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Fully automated analysis of activities catalysed by the major human liver cytochrome P450 (CYP) enzymes: assessment of human CYP inhibition potential

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Light-induced breakdown of flavone acetic acid and xanthenone analogues in solution

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Determination of two major metabolites of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid in hepatic microsomal incubations by high-performance liquid chromatography with fluorescence detection

1 reference

https://api.crossref.org/works/10.1080%2F00498250110092423

21 January 2018

Identifiers

10.1080/00498250110092423

1 reference

Europe PubMed Central

27 November 2017

1 reference

Europe PubMed Central

27 November 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q43898845&oldid=2104241479"