(Q43965445)

English

The UPF3B gene, implicated in intellectual disability, autism, ADHD and childhood onset schizophrenia regulates neural progenitor cell behaviour and neuronal outgrowth

scientific article published on 2 July 2013

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

The UPF3B gene, implicated in intellectual disability, autism, ADHD and childhood onset schizophrenia regulates neural progenitor cell behaviour and neuronal outgrowth (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

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intellectual disability

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based on heuristic

inferred from title

disability affecting intellectual abilities

1 reference

based on heuristic

inferred from title

5

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

object named as

Simon Barry

4

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Lachlan A Jolly

object named as

Lachlan A Jolly

1

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author name string

Claire C Homan

2

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

Reuben Jacob

3

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Europe PubMed Central

PubMed publication ID

28 November 2017

publication date

2 July 2013

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

Human Molecular Genetics

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Europe PubMed Central

PubMed publication ID

28 November 2017

22

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

23

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

4673-4687

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

Genetics of early onset cognitive impairment

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

How much does intellectual disability really cost? First estimates for Australia.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

The genetic landscape of intellectual disability arising from chromosome X.

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Mutations of the UPF3B gene, which encodes a protein widely expressed in neurons, are associated with nonspecific mental retardation with or without autism

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Broadening the phenotype associated with mutations in UPF3B: two further cases with renal dysplasia and variable developmental delay.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

A novel frameshift mutation in UPF3B identified in brothers affected with childhood onset schizophrenia and autism spectrum disorders.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Exome sequencing identifies UPF3B as the causative gene for a Chinese non-syndrome mental retardation pedigree.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Transcriptome profiling of UPF3B/NMD-deficient lymphoblastoid cells from patients with various forms of intellectual disability.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Y14 and hUpf3b form an NMD-activating complex

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

An alternative branch of the nonsense-mediated decay pathway

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

A UPF3-mediated regulatory switch that maintains RNA surveillance

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Genome-wide analysis of mRNAs regulated by the nonsense-mediated and 5' to 3' mRNA decay pathways in yeast

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Gene expression networks: competing mRNA decay pathways in mammalian cells

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Staufen1 regulates diverse classes of mammalian transcripts

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

The exon junction complex component Magoh controls brain size by regulating neural stem cell division.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

The nonsense-mediated decay pathway maintains synapse architecture and synaptic vesicle cycle efficacy.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

The EJC factor eIF4AIII modulates synaptic strength and neuronal protein expression

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Culturing hippocampal neurons

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Depolarization drives beta-Catenin into neuronal spines promoting changes in synaptic structure and function

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

RNA homeostasis governed by cell type-specific and branched feedback loops acting on NMD.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Lentivirus‐mediated expression of insulin‐like growth factor‐I promotes neural stem/precursor cell proliferation and enhances their potential to generate neurons

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Purification of a pluripotent neural stem cell from the adult mouse brain

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Six3 controls the neural progenitor status in the murine CNS

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Importins and exportins in cellular differentiation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Nuclear transport factors in neuronal function

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

The role of the nuclear transport system in cell differentiation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

The role of mammalian Staufen on mRNA traffic: a view from its nucleocytoplasmic shuttling function

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

The cell biology of neurogenesis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Six3 activation of Pax6 expression is essential for mammalian lens induction and specification

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Mutations in the homeodomain of the human SIX3 gene cause holoprosencephaly

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

The role of NrCAM in neural development and disorders--beyond a simple glue in the brain

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Robo1 and Robo2 have distinct roles in pioneer longitudinal axon guidance

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Conserved roles for Slit and Robo proteins in midline commissural axon guidance

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Pioneer longitudinal axons navigate using floor plate and Slit/Robo signals

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Impaired sociability and cognitive function in Nrcam-null mice

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Mutation screening and association analysis of six candidate genes for autism on chromosome 7q

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Association of the neuronal cell adhesion molecule (NRCAM) gene variants with autism

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Association analysis of the NrCAM gene in autism and in subsets of families with severe obsessive-compulsive or self-stimulatory behaviors.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

USP9X enhances the polarity and self-renewal of embryonic stem cell-derived neural progenitors

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Identification of self-replicating multipotent progenitors in the embryonic nervous system by high Notch activity and Hes5 expression

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

A noncoding, regulatory mutation implicates HCFC1 in nonsyndromic intellectual disability

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Linker molecules between laminins and dystroglycan ameliorate laminin-alpha2-deficient muscular dystrophy at all disease stages

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT315

21 January 2018

Identifiers

10.1093/HMG/DDT315

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

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