(Q43985343)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17661907%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

title

The granzyme B gene is highly polymorphic in wild mice but essentially invariant in common inbred laboratory strains (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17661907%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17661907%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

author name string

Kevin Y T Thia

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17661907%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

publication date

1 September 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17661907%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17661907%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

volume

70

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17661907%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17661907%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

page(s)

198-204

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17661907%20AND%20SRC:MED&resulttype=core&format=json

Perforin-mediated target-cell death and immune homeostasis

2 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

Cytotoxic T lymphocyte-induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

The major human and mouse granzymes are structurally and functionally divergent

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

Human and murine granzyme B exhibit divergent substrate preferences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

A triple-mutated allele of granzyme B incapable of inducing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

Granzyme B encoded by the commonly occurring human RAH allele retains pro-apoptotic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

The structure of the pro-apoptotic protease granzyme B reveals the molecular determinants of its specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

Murine cytomegalovirus m157 mutation and variation leads to immune evasion of natural killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

Wild mice: an ever-increasing contribution to a popular mammalian model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, ectromelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

In vitro- and ex vivo-derived cytolytic leukocytes from granzyme A x B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

Effects of non-nucleoside inhibitors of human immunodeficiency virus type 1 in cell-free recombinant reverse transcriptase assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

A novel domain in adenovirus L4-100K is required for stable binding and efficient inhibition of human granzyme B: possible interaction with a species-specific exosite

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2007.00872.X

10.1111/J.1399-0039.2007.00872.X

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17661907%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference