(Q44016910)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12048205%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Distinct dimer interaction and regulation in nitric-oxide synthase types I, II, and III (English)

1 reference

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9 November 2019

1

1 reference

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9 November 2019

5

Elizabeth D Getzoff

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Dennis J Stuehr

6

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author name string

Robin J Rosenfeld

2

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9 November 2019

Sanjay Ghosh

3

1 reference

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9 November 2019

Abigail L Meade

4

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9 November 2019

language of work or name

English

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publication date

4 June 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12048205%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

9 November 2019

number of pages

11

1 reference

based on heuristic

inferred from page(s)

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12048205%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

volume

277

1 reference

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9 November 2019

issue

34

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9 November 2019

page(s)

31020-31030

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The dual personality of NO.

9 November 2019

cites work

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Nitric oxide and macrophage function

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Nitric oxide synthase: aspects concerning structure and catalysis

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Isoforms of nitric oxide synthase. Properties, cellular distribution and expressional control.

21 January 2018

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Cloning and characterization of human inducible nitric oxide synthase splice variants: a domain, encoded by exons 8 and 9, is critical for dimerization

21 January 2018

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Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform

21 January 2018

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Mammalian nitric oxide synthases

21 January 2018

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Crystal structure of the FAD/NADPH-binding domain of rat neuronal nitric-oxide synthase. Comparisons with NADPH-cytochrome P450 oxidoreductase

21 January 2018

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Structure-function aspects in the nitric oxide synthases

21 January 2018

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Characterization of heme-deficient neuronal nitric-oxide synthase reveals a role for heme in subunit dimerization and binding of the amino acid substrate and tetrahydrobiopterin.

21 January 2018

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Endothelial nitric-oxide synthase. Expression in Escherichia coli, spectroscopic characterization, and role of tetrahydrobiopterin in dimer formation.

21 January 2018

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Prokaryotic expression of the heme- and flavin-binding domains of rat neuronal nitric oxide synthase as distinct polypeptides: identification of the heme-binding proximal thiolate ligand as cysteine-415.

21 January 2018

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Characterization of the inducible nitric oxide synthase oxygenase domain identifies a 49 amino acid segment required for subunit dimerization and tetrahydrobiopterin interaction

21 January 2018

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Structure of nitric oxide synthase oxygenase dimer with pterin and substrate

21 January 2018

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Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center

21 January 2018

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Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation

21 January 2018

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Domains of macrophage N(O) synthase have divergent roles in forming and stabilizing the active dimeric enzyme

21 January 2018

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Calmodulin activates intersubunit electron transfer in the neuronal nitric-oxide synthase dimer

21 January 2018

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Heme iron reduction and catalysis by a nitric oxide synthase heterodimer containing one reductase and two oxygenase domains

21 January 2018

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An inducible nitric-oxide synthase (NOS)-associated protein inhibits NOS dimerization and activity

21 January 2018

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Antifungal imidazoles block assembly of inducible NO synthase into an active dimer

21 January 2018

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Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry

21 January 2018

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Mechanistic studies with potent and selective inducible nitric-oxide synthase dimerization inhibitors

21 January 2018

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Nitric oxide synthase: expression and expressional control of the three isoforms.

21 January 2018

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Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha1-syntrophin mediated by PDZ domains

21 January 2018

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Identification, characterization, and comparison of the calmodulin-binding domains of the endothelial and inducible nitric oxide synthases

21 January 2018

1 reference

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Differences in three kinetic parameters underpin the unique catalytic profiles of nitric-oxide synthases I, II, and III.

21 January 2018

1 reference

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Chimeras of nitric-oxide synthase types I and III establish fundamental correlates between heme reduction, heme-NO complex formation, and catalytic activity

21 January 2018

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Calmodulin is a subunit of nitric oxide synthase from macrophages

21 January 2018

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Complementation analysis of mutants of nitric oxide synthase reveals that the active site requires two hemes

21 January 2018

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Subunit interactions of endothelial nitric-oxide synthase. Comparisons to the neuronal and inducible nitric-oxide synthase isoforms

21 January 2018

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High-level expression of functional rat neuronal nitric oxide synthase in Escherichia coli

21 January 2018

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Expression of human inducible nitric oxide synthase in a tetrahydrobiopterin (H4B)-deficient cell line: H4B promotes assembly of enzyme subunits into an active dimer

21 January 2018

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Tetrahydrobiopterin deficiencies without hyperphenylalaninemia: diagnosis and genetics of dopa-responsive dystonia and sepiapterin reductase deficiency.

21 January 2018

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The structure of nitric oxide synthase oxygenase domain and inhibitor complexes

21 January 2018

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Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synthase

21 January 2018

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Inducible nitric oxide synthase: role of the N-terminal beta-hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction

21 January 2018

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The optical interconversion of the P-450 and P-420 forms of neuronal nitric oxide synthase: effects of sodium cholate, mercury chloride and urea.

21 January 2018

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Endothelial nitric oxide synthase: modulations of the distal heme site produced by progressive N-terminal deletions

21 January 2018

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A proteolytically sensitive region common to several rat liver cytochromes P450: effect of cleavage on substrate binding

21 January 2018

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Modulation of the remote heme site geometry of recombinant mouse neuronal nitric-oxide synthase by the N-terminal hook region.

21 January 2018

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N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization.

21 January 2018

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Identification of the domains of neuronal nitric oxide synthase by limited proteolysis

21 January 2018

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Cysteine 99 of endothelial nitric oxide synthase (NOS-III) is critical for tetrahydrobiopterin-dependent NOS-III stability and activity

21 January 2018

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The C331A mutant of neuronal nitric-oxide synthase is defective in arginine binding.

21 January 2018

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Cloning, expression, and characterization of a nitric oxide synthase protein from Deinococcus radiodurans

21 January 2018

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Role of bound zinc in dimer stabilization but not enzyme activity of neuronal nitric-oxide synthase.

21 January 2018

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Haem insertion, dimerization and reactivation of haem-free rat neuronal nitric oxide synthase.

21 January 2018

1 reference

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Tetrahydrobiopterin-deficient nitric oxide synthase has a modified heme environment and forms a cytochrome P-420 analogue

21 January 2018

1 reference

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Structures of tetrahydrobiopterin binding-site mutants of inducible nitric oxide synthase oxygenase dimer and implicated roles of Trp457

21 January 2018

1 reference

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Reactive oxygen species mediate endothelium-dependent relaxations in tetrahydrobiopterin-deficient mice

21 January 2018

1 reference

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Tetrahydrobiopterin biosynthesis, regeneration and functions

21 January 2018

1 reference

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The C termini of constitutive nitric-oxide synthases control electron flow through the flavin and heme domains and affect modulation by calmodulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203749200

21 January 2018

Identifiers

DOI

10.1074/JBC.M203749200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12048205%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference