(Q44068931)

29 November 2017

title

Cancer. Potential of the synthetic lethality principle (English)

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29 November 2017

2

Stephen H Friend

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29 November 2017

Sebastian M B Nijman

1

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29 November 2017

language of work or name

English

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publication date

1 November 2013

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29 November 2017

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29 November 2017

volume

342

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29 November 2017

issue

6160

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29 November 2017

page(s)

809-811

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Integrating genetic approaches into the discovery of anticancer drugs

29 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1244669

The concept of synthetic lethality in the context of anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1244669

Principles of cancer therapy: oncogene and non-oncogene addiction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1244669

The genetic landscape of a cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1244669

The chemical genomic portrait of yeast: uncovering a phenotype for all genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1244669

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1244669

Resistance to therapy caused by intragenic deletion in BRCA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1244669

Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1244669

EGFR-mediated re-activation of MAPK signaling contributes to insensitivity of BRAF mutant colorectal cancers to RAF inhibition with vemurafenib

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1244669

Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1244669

Genotype to phenotype: a complex problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1244669

Predicting mutation outcome from early stochastic variation in genetic interaction partners.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1244669

Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1244669

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1244669

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29 November 2017

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