(Q44109555)

29 November 2017

Phospho-beta-catenin accumulation in Alzheimer's disease and in aggresomes attributable to proteasome dysfunction (English)

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29 November 2017

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Mahin Ghanevati

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29 November 2017

Carol A Miller

series ordinal

2

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29 November 2017

language of work or name

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1 January 2005

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Journal of Molecular Neuroscience

29 November 2017

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29 November 2017

25

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29 November 2017

79-94

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29 November 2017

1

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https://scigraph.springernature.com/pub.10.1385/jmn:25:1:079

29 November 2017

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cites work

Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway

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12 December 2020

Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death.

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12 December 2020

Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease.

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12 December 2020

Wnt signaling function in Alzheimer's disease

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12 December 2020

Ubiquitin-mediated proteolysis: biological regulation via destruction

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12 December 2020

Granulovacuolar degeneration in the hippocampal cortex of aging and demented patients ? a quantitative study

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12 December 2020

The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders

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12 December 2020

Cytoplasmic dynein/dynactin mediates the assembly of aggresomes

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12 December 2020

Beta-catenin: a key mediator of Wnt signaling

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12 December 2020

Proteasome inhibitors induce cytochrome c-caspase-3-like protease-mediated apoptosis in cultured cortical neurons.

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12 December 2020

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

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12 December 2020

Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis

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12 December 2020

Impaired proteasome function in Alzheimer's disease

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12 December 2020

The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

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12 December 2020

Aggresomes: a cellular response to misfolded proteins

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12 December 2020

The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

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12 December 2020

Signal transduction of beta-catenin

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12 December 2020

Total synthesis of the potent proteasome inhibitor epoxomicin: a useful tool for understanding proteasome biology.

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12 December 2020

The active form of glycogen synthase kinase-3beta is associated with granulovacuolar degeneration in neurons in Alzheimer's disease.

1 reference

12 December 2020

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

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12 December 2020

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

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12 December 2020

Activation of the cell death program by inhibition of proteasome function

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12 December 2020

Monoclonal antibody identification of subpopulations of cerebral cortical neurons affected in Alzheimer disease

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12 December 2020

Expanded polyglutamine stretches form an 'aggresome'.

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12 December 2020

Impairment of proteasome structure and function in aging.

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12 December 2020

Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients

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12 December 2020

Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

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12 December 2020

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

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12 December 2020

Reexamination of granulovacuolar degeneration

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12 December 2020

Neuropathological stageing of Alzheimer-related changes

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12 December 2020

Ubiquitin-dependent protein degradation

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12 December 2020

Impairment of the ubiquitin-proteasome system by protein aggregation

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12 December 2020

Dynamic association of proteasomal machinery with the centrosome

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12 December 2020

Molecular misreading: a new type of transcript mutation expressed during aging.

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12 December 2020

Genetic classification of primary neurodegenerative disease.

1 reference

12 December 2020

Lactacystin, a specific inhibitor of the proteasome, induces apoptosis and activates caspase-3 in cultured cerebellar granule cells

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12 December 2020

Proteasome inhibition by the natural products epoxomicin and dihydroeponemycin: insights into specificity and potency.

1 reference

12 December 2020

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12 December 2020

Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin

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12 December 2020

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

1 reference

12 December 2020

Protein misfolding in Alzheimer's and Parkinson's disease: genetics and molecular mechanisms

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12 December 2020

Parkin accumulation in aggresomes due to proteasome impairment

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12 December 2020

Lactacystin, proteasome function, and cell fate

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12 December 2020

Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation

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12 December 2020

Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons

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12 December 2020

Proteasome inhibitors: valuable new tools for cell biologists

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12 December 2020

beta-catenin is a target for the ubiquitin-proteasome pathway

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12 December 2020

Characterisation of the phosphorylation of beta-catenin at the GSK-3 priming site Ser45.

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12 December 2020

Caspase-cleaved amyloid precursor protein and activated caspase-3 are co-localized in the granules of granulovacuolar degeneration in Alzheimer's disease and Down's syndrome brain.

1 reference

12 December 2020

Consensus recommendations for the postmortem diagnosis of Alzheimer disease from the National Institute on Aging and the Reagan Institute Working Group on diagnostic criteria for the neuropathological assessment of Alzheimer disease.

1 reference

12 December 2020

Casein kinase 1 delta is associated with pathological accumulation of tau in several neurodegenerative diseases.

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12 December 2020

Reduction of lipofuscin-like autofluorescence in fluorescently labeled tissue

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12 December 2020

Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

1 reference

12 December 2020

A new molecular link between the fibrillar and granulovacuolar lesions of Alzheimer's disease

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12 December 2020

c-Jun N-terminal kinase pathway mediates Lactacystin-induced cell death in a neuronal differentiated Neuro2a cell line

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12 December 2020

Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro

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12 December 2020

Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease.

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12 December 2020

Signal transduction through beta-catenin and specification of cell fate during embryogenesis

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12 December 2020

Protein kinase C inhibits amyloid beta peptide neurotoxicity by acting on members of the Wnt pathway.

1 reference

12 December 2020

Relationship between beta-amyloid degradation and the 26S proteasome in neural cells

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12 December 2020

Identifiers

DOI

10.1385/JMN:25:1:079

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Dimensions Publication ID

29 November 2017

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