(Q44110006)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12189151%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

title

Malarial dihydroorotate dehydrogenase. Substrate and inhibitor specificity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12189151%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

0 references

3

1 reference

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12 November 2019

5

Margaret A Phillips

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12189151%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

4

Pradipsinh K Rathod

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12189151%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

author name string

Jeffrey Baldwin

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12189151%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Azizeh M Farajallah

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12189151%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

language of work or name

English

0 references

publication date

19 August 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12189151%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

12 November 2019

number of pages

8

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12189151%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

volume

277

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12189151%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

issue

44

1 reference

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12 November 2019

page(s)

41827-41834

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12189151%20AND%20SRC:MED&resulttype=core&format=json

Current status of malaria and potential for control

12 November 2019

cites work

1 reference

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Chloroquine-resistant malaria

21 January 2018

1 reference

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Resistance mutations reveal the atovaquone-binding domain of cytochrome b in malaria parasites

21 January 2018

1 reference

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Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine

21 January 2018

1 reference

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Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine-resistant malaria

21 January 2018

1 reference

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Enzymes of purine and pyrimidine metabolism from the human malaria parasite, Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Purine salvage networks in Giardia lamblia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Purine and pyrimidine metabolism in the Trypanosomatidae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Drug resistance in malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Selective activity of 5-fluoroorotic acid against Plasmodium falciparum in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Molecular targets of 5-fluoroorotate in the human malaria parasite, Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Susceptibility of Plasmodium falciparum to a combination of thymidine and ICI D1694, a quinazoline antifolate directed at thymidylate synthase

21 January 2018

1 reference

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Potent and selective activity of a combination of thymidine and 1843U89, a folate-based thymidylate synthase inhibitor, against Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Pyrimidine Nucleotide Biosynthesis in Animals: Genes, Enzymes, and Regulation of UMP Biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Leflunomide, a novel immunomodulator for the treatment of active rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Leflunomide: an immunomodulatory drug for the treatment of rheumatoid arthritis and other autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Immunosuppressive drugs: the first 50 years and a glance forward

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Site of action of two novel pyrimidine biosynthesis inhibitors accurately predicted by the compare program.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Synthesis, structure-activity relationships, and pharmacokinetic properties of dihydroorotate dehydrogenase inhibitors: 2-cyano-3-cyclopropyl-3-hydroxy-N-[3'-methyl-4'-(trifluoromethyl)phenyl ] propenamide and related compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Divergent evolution of pyrimidine biosynthesis between anaerobic and aerobic yeasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Purification, characterization and localization of mitochondrial dihydroorotate dehydrogenase in Plasmodium falciparum, human malaria parasite

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Purification and characterization of dihydroorotate dehydrogenase from the rodent malaria parasite Plasmodium berghei

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Multiple inhibitor analysis of the brequinar and leflunomide binding sites on human dihydroorotate dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Overcoming codon bias: a method for high-level overexpression of Plasmodium and other AT-rich parasite genes in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

9 Dihydroorotate dehydrogenase (Neurospora)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

The dihydroorotate dehydrogenase gene homologue of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

RNA interference (RNAi) inhibits growth of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206854200

21 January 2018

Identifiers

DOI

10.1074/JBC.M206854200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12189151%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference