(Q44188820)

30 November 2017

title

Synthetic ceramides induce growth arrest or apoptosis by altering cellular redox status (English)

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30 November 2017

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Darren Charles Phillips

series ordinal

1

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30 November 2017

Kirsty Allen

series ordinal

2

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30 November 2017

Helen R Griffiths

series ordinal

3

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30 November 2017

language of work or name

English

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publication date

1 November 2002

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Archives of Biochemistry and Biophysics

30 November 2017

number of pages

10

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based on heuristic

inferred from page(s)

published in

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30 November 2017

volume

407

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30 November 2017

issue

1

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30 November 2017

page(s)

15-24

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Programmed cell death induced by ceramide

30 November 2017

cites work

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Evidence against involvement of the acid lysosomal sphingomyelinase in the tumor-necrosis-factor- and interleukin-1-induced sphingomyelin cycle and cell proliferation in human fibroblasts

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Ceramide-binding and activation defines protein kinase c-Raf as a ceramide-activated protein kinase

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CD95/Fas-induced ceramide formation proceeds with slow kinetics and is not blocked by caspase-3/CPP32 inhibition

7 January 2021

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FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway

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Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

7 January 2021

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Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin

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Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals

7 January 2021

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Daunorubicin activates NFkappaB and induces kappaB-dependent gene expression in HL-60 promyelocytic and Jurkat T lymphoma cells

7 January 2021

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Role of ceramide in lipopolysaccharide (LPS)-induced signaling. LPS increases ceramide rather than acting as a structural homolog

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Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

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A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinase

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7 January 2021

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Retinoblastoma gene product as a downstream target for a ceramide-dependent pathway of growth arrest

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Bcl-2 interrupts the ceramide-mediated pathway of cell death.

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PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid

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7 January 2021

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Endothelial cell inflammatory responses to tumor necrosis factor alpha. Ceramide-dependent and -independent mitogen-activated protein kinase cascades

7 January 2021

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Ceramide in apoptosis signaling: relationship with oxidative stress

7 January 2021

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Functions of glutathione and glutathione disulfide in immunology and immunopathology.

7 January 2021

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Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-kappaB.

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Caspase-dependent ceramide production in Fas- and HLA class I-mediated peripheral T cell apoptosis

7 January 2021

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Flow cytometric measurement of the respiratory burst activity of phagocytes using dihydrorhodamine 123

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species

7 January 2021

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Effect of ceramide on intracellular glutathione determines apoptotic or necrotic cell death of JB6 tumor cells

7 January 2021

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7 January 2021

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7 January 2021

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Interaction with substrate sensitises caspase-3 to inactivation by hydrogen peroxide.

7 January 2021

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Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease

7 January 2021

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7 January 2021

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Ceramide Induces CytochromecRelease from Isolated Mitochondria

7 January 2021

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The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis

7 January 2021

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Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide

7 January 2021

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Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss

7 January 2021

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Thioredoxin peroxidase is a novel inhibitor of apoptosis with a mechanism distinct from that of Bcl-2

7 January 2021

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Redox regulatory mechanisms of cellular signal transduction

7 January 2021

1 reference

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Ceramide potentiates, but sphingomyelin inhibits, vitamin D-induced keratinocyte differentiation: comparison between keratinocytes and HL-60 cells

7 January 2021

1 reference

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On the complexities of ceramide changes in cells undergoing apoptosis: lack of evidence for a second messenger function in apoptotic induction

7 January 2021

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Ceramide induces Bcl2 dephosphorylation via a mechanism involving mitochondrial PP2A

7 January 2021

1 reference

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Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A. Activation is stereospecific and regulated by phosphatidic acid

7 January 2021

1 reference

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10.1016/S0003-9861(02)00496-4

7 January 2021

Identifiers

DOI

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30 November 2017

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