(Q44210260)

30 November 2017

title

Increased CNS uptake and enhanced antinociception of morphine-6-glucuronide in rats after inhibition of P-glycoprotein (English)

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30 November 2017

1

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30 November 2017

7

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30 November 2017

6

Gerd Geisslinger

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30 November 2017

3

Gregor Vetter

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30 November 2017

5

Ellen Niederberger

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30 November 2017

Rodolfo Schmidt

2

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30 November 2017

Helmut Schmidt

series ordinal

4

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30 November 2017

language of work or name

English

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publication date

1 October 2002

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Journal of Neurochemistry

30 November 2017

published in

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30 November 2017

volume

83

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30 November 2017

issue

2

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30 November 2017

page(s)

241-248

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Morphine-6-glucuronide: analgesic effects and receptor binding profile in rats

30 November 2017

cites work

1 reference

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Insidious intoxication after morphine treatment in renal failure: delayed onset of morphine-6-glucuronide action

21 January 2018

1 reference

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P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain

21 January 2018

1 reference

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MOAT-E (ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

Blood-brain barrier transport and brain distribution of morphine-6-glucuronide in relation to the antinociceptive effect in rats--pharmacokinetic/pharmacodynamic modelling

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

Organ distribution of multidrug resistance proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and hepatic induction of Mrp3 by constitutive androstane receptor activators in rats

21 January 2018

1 reference

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Isolation of endothelial cells from brain, lung, and kidney: expression of the multidrug resistance P-glycoprotein isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

Effect of P-glycoprotein modulation on the clinical pharmacokinetics and adverse effects of morphine

21 January 2018

1 reference

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The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats

21 January 2018

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Localization of the organic anion transporting polypeptide 2 (Oatp2) in capillary endothelium and choroid plexus epithelium of rat brain

21 January 2018

1 reference

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Inhibition of noxious stimulus-induced spinal prostaglandin E2 release by flurbiprofen enantiomers: a microdialysis study

21 January 2018

1 reference

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Expression of multidrug resistance-associated protein (MRP) in brain microvessel endothelial cells.

21 January 2018

1 reference

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Evidence for P-glycoprotein-modulated penetration of morphine-6-glucuronide into brain capillary endothelium

21 January 2018

1 reference

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Cellular and molecular aspects of drug transport in the kidney

21 January 2018

1 reference

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Functional analysis and androgen-regulated expression of mouse organic anion transporting polypeptide 1 (Oatp1) in the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

Expression cloning of a rat liver Na(+)-independent organic anion transporter

21 January 2018

1 reference

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A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

21 January 2018

1 reference

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Transport of the beta -O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1). Requirement for glutathione or a non-sulfur-containing analog

21 January 2018

1 reference

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Antinociceptive effects of morphine-6-glucuronide in homozygous MDR1a P-glycoprotein knockout and in wildtype mice in the hotplate test

21 January 2018

1 reference

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The transfer half-life of morphine-6-glucuronide from plasma to effect site assessed by pupil size measurement in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

Developmental expression of P-glycoprotein (multidrug resistance gene product) in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

Morphine intoxication in renal failure: the role of morphine-6-glucuronide

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

Opiate-induced analgesia is increased and prolonged in mice lacking P-glycoprotein

21 January 2018

1 reference

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Morphine-6-glucuronide concentrations and opioid-related side effects: a survey in cancer patients

21 January 2018

1 reference

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Restricted transport of cyclosporin A across the blood-brain barrier by a multidrug transporter, P-glycoprotein.

21 January 2018

1 reference

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Modelling of the blood-brain barrier transport of morphine-3-glucuronide studied using microdialysis in the rat: involvement of probenecid-sensitive transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

Two apical multidrug transporters, P-gp and MRP2, are differently altered in chronic renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

Pharmacological validation of an automated method of pain scoring in the formalin test in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

Mrp1 multidrug resistance-associated protein and P-glycoprotein expression in rat brain microvessel endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

Cellular localization of P-glycoprotein in brain versus gonadal capillaries

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

Expression of various multidrug resistance-associated protein (MRP) homologues in brain microvessel endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01177.X

10.1046/J.1471-4159.2002.01177.X

21 January 2018

Identifiers

DOI

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release_wuq6u4owy5bg3jtrxsut5mal4y

30 November 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/wuq6u4owy5bg3jtrxsut5mal4y

mapped directly with Wikidata item

24 November 2022

based on heuristic

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