(Q44225651)

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Molecular mechanisms underlying cyclic AMP inhibition of macrophage dependent TNF-alpha production and neurotoxicity in response to amyloidogenic C-terminal fragment of Alzheimer's amyloid precursor protein

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Europe PubMed Central

PubMed publication ID

1 December 2017

Molecular mechanisms underlying cyclic AMP inhibition of macrophage dependent TNF-alpha production and neurotoxicity in response to amyloidogenic C-terminal fragment of Alzheimer's amyloid precursor protein (English)

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Europe PubMed Central

PubMed publication ID

1 December 2017

Alzheimer's disease

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inferred from title

toxic encephalopathy

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5

object named as

Yoo-Hun Suh

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Europe PubMed Central

PubMed publication ID

1 December 2017

author name string

Young Hae Chong

1

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Europe PubMed Central

PubMed publication ID

1 December 2017

Soon Ah Shin

2

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Europe PubMed Central

PubMed publication ID

1 December 2017

Hyun Joo Lee

3

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Europe PubMed Central

PubMed publication ID

1 December 2017

Ji Hee Lee Kang

4

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Europe PubMed Central

PubMed publication ID

1 December 2017

publication date

1 December 2002

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Europe PubMed Central

PubMed publication ID

1 December 2017

Journal of Neuroimmunology

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Europe PubMed Central

PubMed publication ID

1 December 2017

133

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Europe PubMed Central

PubMed publication ID

1 December 2017

1-2

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Europe PubMed Central

PubMed publication ID

1 December 2017

160-174

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Europe PubMed Central

PubMed publication ID

1 December 2017

Up-regulation of the inflammatory cytokines IFN-gamma and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APP(SWE) transgenic mice

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https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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Inflammation and Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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beta-Amyloid neurotoxicity is exacerbated during glycolysis inhibition and mitochondrial impairment in the rat hippocampus in vivo and in isolated nerve terminals: implications for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

CREB1 encodes a nuclear activator, a repressor, and a cytoplasmic modulator that form a regulatory unit critical for long-term facilitation

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https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Heparin attenuates cytotoxic and inflammatory activity of Alzheimer amyloid-beta in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Impairments in learning and memory accompanied by neurodegeneration in mice transgenic for the carboxyl-terminus of the amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Does IFNgamma play a role in neurodegeneration?

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7 January 2021

based on heuristic

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Expression of human beta-secretase in the mouse brain increases the steady-state level of beta-amyloid.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

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Neuronal degeneration in locus ceruleus and cortical correlates of Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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A High Plasma Concentration of TNF- Is Associated With Dementia in Centenarians

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Catecholamines inhibit microglial nitric oxide production

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Effect of a carboxy-terminal fragment of the Alzheimer's amyloid precursor protein on expression of proinflammatory cytokines in rat glial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Effects of the beta-amyloid and carboxyl-terminal fragment of Alzheimer's amyloid precursor protein on the production of the tumor necrosis factor-alpha and matrix metalloproteinase-9 by human monocytic THP-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Association of a haplotype for tumor necrosis factor in siblings with late-onset Alzheimer disease: the NIMH Alzheimer Disease Genetics Initiative

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Neurotoxic APP C-terminal and β-amyloid domains colocalize in the nuclei of substantia nigra pars reticulata neurons undergoing delayed degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of astroglial nitric oxide synthase expression by norepinephrine results from decreased NOS-2 promoter activity

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

NF-kB immunoreactivity is observed in association with beta A4 diffuse plaques in patients with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Elevated circulating tumor necrosis factor levels in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Membrane currents induced in Xenopus oocytes by the C-terminal fragment of the beta-amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Norepinephrine increases I kappa B alpha expression in astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Disease-specific patterns of locus coeruleus cell loss

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for an interferon-related inflammatory reaction in the trisomy 16 mouse brain leading to caspase-1-mediated neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Noradrenergic depletion potentiates beta -amyloid-induced cortical inflammation: implications for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Three NF-kappa B sites in the I kappa B-alpha promoter are required for induction of gene expression by TNF alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

IFNgamma enhances microglial reactions to hippocampal axonal degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

APP transgenic mice Tg2576 accumulate Abeta peptides that are distinct from the chemically modified and insoluble peptides deposited in Alzheimer's disease senile plaques.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Neurotoxicity of a carboxyl-terminal fragment of the Alzheimer's amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Carboxyl-terminal fragment of Alzheimer's APP destabilizes calcium homeostasis and renders neuronal cells vulnerable to excitotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Use-dependent effects of amyloidogenic fragments of (beta)-amyloid precursor protein on synaptic plasticity in rat hippocampus in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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The neurotoxic carboxy-terminal fragment of the Alzheimer amyloid precursor binds specifically to a neuronal cell surface molecule: pH dependence of the neurotoxicity and the binding

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Longitudinal study of inflammatory factors in serum, cerebrospinal fluid, and brain tissue in Alzheimer disease: interleukin-1beta, interleukin-6, interleukin-1 receptor antagonist, tumor necrosis factor-alpha, the soluble tumor necrosis factor rece

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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APP carboxyl-terminal fragment without or with abeta domain equally induces cytotoxicity in differentiated PC12 cells and cortical neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A betaPP peptide carboxyl-terminal to Abeta is neurotoxic

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Altered processing characteristics of beta-amyloid-containing peptides in cytosol and in media of familial Alzheimer's disease cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Roles of nuclear factor kappaB in neuronal survival and plasticity

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Neuronal expression of beta-amyloid precursor protein Alzheimer mutations causes intracellular accumulation of a C-terminal fragment containing both the amyloid beta and cytoplasmic domains

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Decrease in adenylate cyclase activity antecedes neurofibrillary tangle formation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

G-protein coupled signal transduction systems in the Alzheimer's disease brain

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of nitrite production by human monocyte-derived macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of carboxyl-terminal fragment of Alzheimer's amyloid precursor protein and amyloid beta-peptide on the production of cytokines and nitric oxide in glial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Microglial chemotaxis, activation, and phagocytosis of amyloid beta-peptide as linked phenomena in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Cascading glia reactions: a common pathomechanism and its differentiated control by cyclic nucleotide signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of tumor necrosis factor alpha production by cAMP in human monocytes: dissociation with mRNA level and independent of interleukin-10.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Macrophage and microglial responses to cytokines in vitro: phagocytic activity, proteolytic enzyme release, and free radical production

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Intracellular pathways involved in TNF-alpha and superoxide anion release by Abeta(1-42)-stimulated primary human macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Hemorheological changes and overproduction of cytokines from immune cells in mild to moderate dementia of the Alzheimer's type: adverse effects on cerebromicrovascular system

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Behavioral and neuropathologic changes induced by central injection of carboxyl-terminal fragment of beta-amyloid precursor protein in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Late-onset chronic inflammatory encephalopathy in immune-competent and severe combined immune-deficient (SCID) mice with astrocyte-targeted expression of tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

An etiological role of amyloidogenic carboxyl-terminal fragments of the beta-amyloid precursor protein in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a stable fragment of the Alzheimer amyloid precursor containing the beta-protein in brain microvessels

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Occurrence of T cells in the brain of Alzheimer's disease and other neurological diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Serum levels of gamma interferon in patients with Down's syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Human microglial cells have phenotypic and functional characteristics in common with both macrophages and dendritic antigen-presenting cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

RETRACTED: A new mechanism of neurodegeneration: a proinflammatory cytokine inhibits receptor signaling by a survival peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factor(alpha) and insulin-like growth factor-I in the brain: is the whole greater than the sum of its parts?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Age- and concentration-dependent neuroprotection and toxicity by TNF in cortical neurons from beta-amyloid

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Hippocampal level of neural specific adenylyl cyclase type I is decreased in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Impaired phosphorylation of cyclic AMP response element binding protein in the hippocampus of dementia of the Alzheimer type

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Target depletion of distinct tumor necrosis factor receptor subtypes reveals hippocampal neuron death and survival through different signal transduction pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

CREB and the formation of long-term memory

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Neuroprotective and neurotrophic efficacy of phytoestrogens in cultured hippocampal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2802%2900349-1

7 January 2021

based on heuristic

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Identifiers

10.1016/S0165-5728(02)00349-1

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

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