(Q44270673)

1 December 2017

title

Promotion of DNA repair by nuclear IKKβ phosphorylation of ATM in response to genotoxic stimuli (English)

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1 December 2017

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K Sakamoto

1

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1 December 2017

Y Hikiba

2

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1 December 2017

H Nakagawa

3

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1 December 2017

Y Hirata

4

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1 December 2017

Y Hayakawa

5

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1 December 2017

H Kinoshita

6

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1 December 2017

W Nakata

7

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1 December 2017

K Sakitani

8

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1 December 2017

R Takahashi

9

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1 December 2017

M Akanuma

10

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1 December 2017

H Kamata

11

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1 December 2017

S Maeda

12

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1 December 2017

language of work or name

English

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publication date

21 May 2012

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1 December 2017

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1 December 2017

volume

32

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1 December 2017

issue

14

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1 December 2017

page(s)

1854-1862

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The DNA-damage response in human biology and disease

1 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

ATM: a mediator of multiple responses to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Accumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

3-Nitrobenzanthrone and 3-aminobenzanthrone induce DNA damage and cell signalling in Hepa1c1c7 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Loss of ATM sensitizes against O6-methylguanine triggered apoptosis, SCEs and chromosomal aberrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

ATM activation by oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

ATM is required for IkappaB kinase (IKKk) activation in response to DNA double strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Nuclear initiated NF-κB signaling: NEMO and ATM take center stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Missing pieces in the NF-kappaB puzzle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Ikappa B kinasebeta/nuclear factor-kappaB activation controls the development of liver metastasis by way of interleukin-6 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-α feedforward signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

ATM promotes apoptosis and suppresses tumorigenesis in response to Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Determination of apurinic/apyrimidinic lesions in DNA with high-performance liquid chromatography and tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Quantification of DNA strand breaks and abasic sites by oxime derivatization and accelerator mass spectrometry: application to gamma-radiation and peroxynitrite

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

IKKβ regulates the repair of DNA double-strand breaks induced by ionizing radiation in MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

IKK and NF-kappaB-mediated regulation of Claspin impacts on ATR checkpoint function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Inflammation and cancer: role of nuclear factor-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Cell-cycle checkpoints and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

The DNA damage response: putting checkpoints in perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Inhibitor of kappaB kinase beta regulates gastric carcinogenesis via interleukin-1alpha expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Nuclear IKKβ Is an Adaptor Protein for IκBα Ubiquitination and Degradation in UV-Induced NF-κB Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Activation of ATM depends on chromatin interactions occurring before induction of DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Involvement of novel autophosphorylation sites in ATM activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

HMGA proteins promote ATM expression and enhance cancer cell resistance to genotoxic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Replication stress activates DNA polymerase alpha-associated Chk1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Helicobacter pylori induces IkappaB kinase alpha nuclear translocation and chemokine production in gastric epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

KinasePhos 2.0: a web server for identifying protein kinase-specific phosphorylation sites based on sequences and coupling patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

The protective role of thiol reducing agents in the in vitro inhibition of rat liver DNA methylase by direct acting carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

The response of Parp knockout mice against DNA damaging agents.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.192

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.192

1 reference

Dimensions Publication ID

1 December 2017

1044855855

0 references

1 reference