(Q44383130)

English

Presenilin-1 mutation sensitizes oligodendrocytes to glutamate and amyloid toxicities, and exacerbates white matter damage and memory impairment in mice

scientific article published in January 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

Presenilin-1 mutation sensitizes oligodendrocytes to glutamate and amyloid toxicities, and exacerbates white matter damage and memory impairment in mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

oligodendrocyte

1 reference

based on heuristic

inferred from title

3

object named as

Mark P Mattson

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Europe PubMed Central

PubMed publication ID

2 December 2017

author name string

Kirk Pak

1

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

Sic L Chan

2

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

publication date

1 January 2003

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

NeuroMolecular Medicine

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

53-64

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

Activation of AP-1 and Nuclear Factor-κB Transcription Factors Is Involved in Hydrogen Peroxide-Induced Apoptotic Cell Death of Olligodendrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ion channel redistribution and function during development of the myelinated axon

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of Alzheimer-type pathologic changes in nondemented elderly individuals matches the pattern in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperactivity, neuromotor defects, and impaired learning and memory in a mouse model for metachromatic leukodystrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of ryanodine receptors in oligodendrocytes, type 2 astrocytes, and O-2A progenitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural changes in ageing and dementia of Alzheimer's type with special reference to recent etiologic and therapeutic theories

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prominent expression of presenilin-1 in senile plaques and reactive astrocytes in Alzheimer's disease brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

White matter amyloid in Alzheimer's disease brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta peptides are cytotoxic to oligodendrocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased brain levels of 2',3'-cyclic nucleotide-3'-phosphodiesterase in Down syndrome and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Alzheimer's disease: the beta amyloid protein A4 is also present in the cortical white matter]

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive oxygen species mediate activity-dependent neuron-glia signaling in output fibers of the hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of specific association of presenilin 1 (PS-1) protein with plaques and tangles in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axonal pathology in myelin disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for oligodendrocyte-derived IGF-1 in trophic support of cortical neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative histochemistry of myelin using Luxol Fast Blue MBS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-death properties of TNF against metabolic poisoning: mitochondrial stabilization by MnSOD.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: genetic studies and transgenic models

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligodendrocytes as providers of growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial/macrophage accumulation during cuprizone-induced demyelination in C57BL/6 mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiology of oligodendroglial excitotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central nervous system demyelination and remyelination in the mouse: an ultrastructural study of cuprizone toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axonal degeneration is an early pathological feature in autoimmune-mediated demyelination in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine oligodendroglial cells express nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial expression of presenilin epitopes in human brain with cerebral infarction and in astrocytoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Magnetic resonance imaging in dementia. A study of brain white matter changes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebroside synthesis as a measure of the rate of remyelination following cuprizone-induced demyelination in brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiology and pathophysiology of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cognitive decline in patients with familial Alzheimer's disease associated with E280a presenilin-1 mutation: a longitudinal study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myelination of cortical-hippocampal relays during late adolescence

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca(2+) influx through AMPA or kainate receptors alone is sufficient to initiate excitotoxicity in cultured oligodendrocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maturation-dependent vulnerability of oligodendrocytes to oxidative stress-induced death caused by glutathione depletion

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunofluorescence demonstration of 2′:3′-cyclic-nucleotide 3′-phosphodiesterase in cultured oligodendrocytes of mouse, rat, calf and human

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spatial learning in transgenic mice expressing human presenilin 1 (PS1) transgenes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Learning abilities, NGF and BDNF brain levels in two lines of TNF-alpha transgenic mice, one characterized by neurological disorders, the other phenotypically normal

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical localization of myelin basic protein and 2',3'-cyclic nucleotide 3'-phosphohydrolase in flattened membrane expansions produced by cultured oligodendrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uptake of potassium by nonmyelinating Schwann cells induced by axonal activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12665676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1385/NMM:3:1:53

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

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