(Q44456255)

3 December 2017

title

Chemical genetic modifier screens: small molecule trichostatin suppressors as probes of intracellular histone and tubulin acetylation (English)

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3 December 2017

Brian D Perkins

3

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ORCID Public Data File 2021

Stuart Schreiber

7

object named as

Stuart L Schreiber

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3 December 2017

Kathryn M Koeller

1

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3 December 2017

Stephen J Haggarty

2

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3 December 2017

Igor Leykin

4

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3 December 2017

Jason C Wong

5

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3 December 2017

Ming-Chih J Kao

6

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3 December 2017

publication date

1 May 2003

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3 December 2017

published in

Chemistry and Biology

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3 December 2017

volume

10

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3 December 2017

issue

5

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3 December 2017

page(s)

397-410

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Histone deacetylases, transcriptional control, and cancer

3 December 2017

cites work

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Histone deacetylases and cancer: causes and therapies

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Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a case report

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7 January 2021

Polyglutamine disease: acetyltransferases awry

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7 January 2021

A common mechanism of action for three mood-stabilizing drugs

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7 January 2021

Deacetylase enzymes: biological functions and the use of small-molecule inhibitors

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7 January 2021

High-throughput screening of small molecules in miniaturized mammalian cell-based assays involving post-translational modifications

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7 January 2021

Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small molecules that perturb mitosis

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7 January 2021

A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

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7 January 2021

Signaling network model of chromatin

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FR901228, a potent antitumor antibiotic, is a novel histone deacetylase inhibitor.

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Molecular cloning and characterization of a novel histone deacetylase HDAC10

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7 January 2021

Microtubules containing acetylated alpha-tubulin in mammalian cells in culture

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7 January 2021

HDAC6 is a microtubule-associated deacetylase

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7 January 2021

Multidimensional chemical genetic analysis of diversity-oriented synthesis-derived deacetylase inhibitors using cell-based assays

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7 January 2021

Synthesis of 7200 small molecules based on a substructural analysis of the histone deacetylase inhibitors trichostatin and trapoxin

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7 January 2021

Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

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7 January 2021

Small molecule developmental screens reveal the logic and timing of vertebrate development

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7 January 2021

Retinoic acid alters photoreceptor development in vivo

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7 January 2021

Transgenic expression of a GFP-rhodopsin COOH-terminal fusion protein in zebrafish rod photoreceptors

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7 January 2021

Genomewide studies of histone deacetylase function in yeast

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7 January 2021

The Pit-1beta domain dictates active repression and alteration of histone acetylation of the proximal prolactin promoter

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7 January 2021

Repression of the mouse M-lysozyme gene involves both hindrance of enhancer factor binding to the methylated enhancer and histone deacetylation

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7 January 2021

Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A

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7 January 2021

"Stemness": transcriptional profiling of embryonic and adult stem cells

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7 January 2021

Photoaffinity labeling and mass spectrometry identify ribosomal protein S3 as a potential target for hybrid polar cytodifferentiation agents

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7 January 2021

Histone deacetylase inhibitor activates the WAF1/Cip1 gene promoter through the Sp1 sites

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7 January 2021

Retinoblastoma protein recruits histone deacetylase to repress transcription

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7 January 2021

HDAC4 deacetylase associates with and represses the MEF2 transcription factor

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7 January 2021

A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p

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7 January 2021

Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells.

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7 January 2021

A role for histone deacetylase activity in HDAC1-mediated transcriptional repression

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7 January 2021

10.1016/S1074-5521(03)00093-0

Identifiers

DOI

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3 December 2017

1 reference