(Q44539049)

3 December 2017

title

Benzofuranyl 3,5-bis-polyamine derivatives as time-dependent inhibitors of trypanothione reductase (English)

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3 December 2017

3

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3 December 2017

Ian M Eggleston

4

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Ahilan Saravanamuthu

series ordinal

2

object named as

Ahilan Saravanamuthu

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3 December 2017

Chris J Hamilton

1

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3 December 2017

language of work or name

English

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publication date

1 August 2003

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Bioorganic & Medicinal Chemistry

3 December 2017

published in

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3 December 2017

volume

11

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3 December 2017

issue

17

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3 December 2017

page(s)

3683-3693

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Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids

3 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2803%2900344-4

7 January 2021

Metabolism and functions of trypanothione in the Kinetoplastida

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7 January 2021

Disruption of the trypanothione reductase gene of Leishmania decreases its ability to survive oxidative stress in macrophages.

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7 January 2021

Evidence that trypanothione reductase is an essential enzyme in Leishmania by targeted replacement of the tryA gene locus

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https://api.crossref.org/works/10.1016%2FS0968-0896%2803%2900344-4

7 January 2021

Down-regulation of Leishmania donovani trypanothione reductase by heterologous expression of a trans-dominant mutant homologue: effect on parasite intracellular survival

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https://api.crossref.org/works/10.1016%2FS0968-0896%2803%2900344-4

7 January 2021

Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress

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https://api.crossref.org/works/10.1016%2FS0968-0896%2803%2900344-4

7 January 2021

Charge is the major discriminating factor for glutathione reductase versus trypanothione reductase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2803%2900344-4

7 January 2021

Substrate specificity of the flavoprotein trypanothione disulfide reductase from Crithidia fasciculata

1 reference

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7 January 2021

Optimising inhibitors of trypanothione reductase using solid-phase chemistry

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2803%2900344-4

7 January 2021

Kukoamine A and other hydrophobic acylpolyamines: potent and selective inhibitors of Crithidia fasciculata trypanothione reductase.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2803%2900344-4

7 January 2021

Crystal structure of Trypanosoma cruzi trypanothione reductase in complex with trypanothione, and the structure-based discovery of new natural product inhibitors

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https://api.crossref.org/works/10.1016%2FS0968-0896%2803%2900344-4

7 January 2021

Regiocontrolled synthesis of the macrocyclic polyamine alkaloid (±)-lunarine, a time-dependent inhibitor of trypanothione reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2803%2900344-4

7 January 2021

Synthesis of 5,5'-dithiobis(2-nitrobenzamides) as alternative substrates for trypanothione reductase and thioredoxin reductase: a microtiter colorimetric assay for inhibitor screening

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2803%2900344-4

7 January 2021

Total Synthesis of Garcifuran B

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https://api.crossref.org/works/10.1016%2FS0968-0896%2803%2900344-4

7 January 2021

Ueber das 1- und 2-Brom-cumaron

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https://api.crossref.org/works/10.1016%2FS0968-0896%2803%2900344-4

7 January 2021

Dimethylformamide as a Useful Solvent in Preparing Nitriles from Aryl Halides and Cuprous Cyanide; Improved Isolation Techniques1a

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7 January 2021

Ellman's-reagent-mediated regeneration of trypanothione in situ: substrate-economical microplate and time-dependent inhibition assays for trypanothione reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2803%2900344-4

7 January 2021

Site-directed mutagenesis of the redox-active cysteines of Trypanosoma cruzi trypanothione reductase.

1 reference

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7 January 2021

Human glutathione reductase: purification of the crystalline enzyme from erythrocytes.

1 reference

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7 January 2021

Glutathione Reductase from Human Erythrocytes. Catalytic Properties and Aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2803%2900344-4

7 January 2021

10.1016/S0968-0896(03)00344-4

Identifiers

DOI

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3 December 2017

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