(Q44567534)

English

The cholesterol-lowering drug probucol increases apolipoprotein E production in the hippocampus of aged rats: implications for Alzheimer's disease

scientific article published in January 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

The cholesterol-lowering drug probucol increases apolipoprotein E production in the hippocampus of aged rats: implications for Alzheimer's disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Alzheimer's disease

0 references

author name string

Champagne D

1

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Pearson D

2

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Dea D

3

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Rochford J

4

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Poirier J

5

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

language of work or name

0 references

publication date

1 January 2003

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

121

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

99-110

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Increased levels of messenger ribonucleic acid for apolipoprotein E in the spleen of probucol-treated rabbits

1 reference

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Plastic neuronal remodeling is impaired in patients with Alzheimer's disease carrying apolipoprotein epsilon 4 allele

1 reference

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7 January 2021

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Apolipoprotein E and beta-amyloid levels in the hippocampus and frontal cortex of Alzheimer's disease subjects are disease-related and apolipoprotein E genotype dependent

1 reference

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7 January 2021

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The neurobiology of apolipoproteins and their receptors in the CNS and Alzheimer's disease

1 reference

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7 January 2021

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Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein J (clusterin) in Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

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Discrepancies between the outcome of animal and human studies on the mode of action of probucol

1 reference

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7 January 2021

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Cerebrospinal fluid apolipoprotein E is reduced in Alzheimer's disease.

1 reference

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7 January 2021

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A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve

1 reference

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7 January 2021

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beta-Hydroxy-beta-methyl-glutaryl coenzyme A reductase, cleavage and condensing enzymes in relation to cholesterol formation in rat liver

1 reference

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7 January 2021

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Clinical relevance of the quantification of apolipoprotein E in cerebrospinal fluid

1 reference

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7 January 2021

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Reversal of presynaptic deficits of apolipoprotein E-deficient mice in human apolipoprotein E transgenic mice.

1 reference

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7 January 2021

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Motor and cognitive deficits in apolipoprotein E-deficient mice after closed head injury.

1 reference

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7 January 2021

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Atorvastatin and simvastatin have distinct effects on hydroxy methylglutaryl-CoA reductase activity and mRNA abundance in the guinea pig

1 reference

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7 January 2021

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Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

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7 January 2021

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Apolipoprotein E polymorphism and atherosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Gonadal steroids regulate the expression of glial fibrillary acidic protein in the adult male rat hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

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inferred from DOI database lookup

Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

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Differential effects of lovastatin treatment on brain cholesterol levels in normal and apoE-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

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Glial fibrillary acidic protein (GFAP): the major protein of glial intermediate filaments in differentiated astrocytes

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

GFAP and astrogliosis

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E-containing high density lipoprotein promotes neurite outgrowth and is a ligand for the low density lipoprotein receptor-related protein

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Age-dependent decline in the apolipoprotein E level in cerebrospinal fluid from control subjects and its increase in cerebrospinal fluid from patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Gonadal hormones down-regulate reactive gliosis and astrocyte proliferation after a penetrating brain injury

1 reference

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7 January 2021

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A highly conserved signal controls degradation of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase in eukaryotes

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Genotype-related differences of hippocampal apolipoprotein E levels only in early stages of neuropathological changes in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of the mevalonate pathway

1 reference

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7 January 2021

based on heuristic

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Exaggerated astrocyte reactivity after nigrostriatal deafferentation in the aged rat.

1 reference

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7 January 2021

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An immunohistochemical quantification of fibrous astrocytes in the aging human cerebral cortex

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

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Apolipoprotein E receptors: linking brain development and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

A quantitative and immunohistochemical study on apolipoprotein E in brain tissue in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Measurement of apolipoprotein E (apoE) in cerebrospinal fluid

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

A new type of lesion-induced synaptogenesis: II. The effect of aging on synaptic turnover in non-denervated zones

1 reference

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7 January 2021

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inferred from DOI database lookup

Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of probucol on plasma lipoprotein subfractions and activities of lipoprotein lipase and hepatic triglyceride lipase

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of apolipoprotein E during nerve degeneration and regeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression and distribution of low density lipoprotein receptor-related protein mRNA in the rat central nervous system.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Statins and the risk of dementia

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Prevention of atherosclerotic progression in Watanabe rabbits by probucol

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The effects of age, apolipoprotein E phenotype and gender on the concentration of amyloid-beta (A beta) 40, A beta 4242, apolipoprotein E and transthyretin in human cerebrospinal fluid

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E and apolipoprotein E receptors modulate A beta-induced glial neuroinflammatory responses

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Patterns of astroglial hypertrophy and neuronal degeneration in the hippocampus of ages, memory-deficient rats

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E suppresses glial cell secretion of TNF alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E and the CNS response to injury.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E-deficient mice have increased susceptibility to focal cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Relevance of the quantification of apolipoprotein E in the cerebrospinal fluid in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E (apoE) polymorphism and its influence on ApoE concentrations in the cerebrospinal fluid in Finnish patients with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Allelic discrimination using fluorogenic probes and the 5' nuclease assay

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E modulates glial activation and the endogenous central nervous system inflammatory response.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Neurodegeneration in the central nervous system of apoE-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

CNS synaptogenesis promoted by glia-derived cholesterol

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

HMG-CoA reductase inhibitors and the risk of fractures

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The mosaic of brain glial hyperactivity during normal ageing and its attenuation by food restriction

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The low-density lipoprotein receptor-related protein, a multifunctional apolipoprotein E receptor, modulates hippocampal neurite development

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E4 inhibits, and apolipoprotein E3 promotes neurite outgrowth in cultured adult mouse cortical neurons through the low-density lipoprotein receptor-related protein

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Feedback and hormonal regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase: the concept of cholesterol buffering capacity

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Food restriction delays the age-related increase in GFAP mRNA in rat hypothalamus

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Astrocytic messenger RNA responses to striatal deafferentation in male rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

A new mathematical model for relative quantification in real-time RT-PCR

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E polymorphism and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Astrocytic apolipoprotein E mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxidative insults are associated with apolipoprotein E genotype in Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Tau protein and apolipoprotein E in CSF diagnostics of Alzheimer's disease: impact on non Alzheimer's dementia?

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Decline in reactive fiber growth in the dentate gyrus of aged rats compared to young adult rats following entorhinal cortex removal.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Quantitative reverse transcription-polymerase chain reaction to study mRNA decay: comparison of endpoint and real-time methods

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Influence of probucol on early experimental atherogenesis in hypercholesterolemic rats

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Hydroxymethylglutaryl-coenzyme A reductase-containing hepatocytes are distributed periportally in normal and mevinolin-treated rat livers

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E in cerebrospinal fluid in 85-year-old subjects. Relation to dementia, apolipoprotein E polymorphism, cerebral atrophy, and white matter lesions.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Neurotransmission: harnessing fusion machinery at the synapse

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Cerebrospinal fluid apo E and apo A-I concentrations in early- and late-onset Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Astrocytes and microglia respond to estrogen with increased apoE mRNA in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of age on gene expression during estrogen-induced synaptic sprouting in the female rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Membrane lipids in the aging human brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Mode of action of probucol in reducing serum cholesterol in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of apolipoprotein E and estrogen in mossy fiber sprouting in hippocampal slice cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Dynamics of gene expression for microtubule-associated protein MAP1B, embryonic alpha-tubulin and late neural beta-tubulin mRNAs in the hippocampus of aged rats

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E mRNA in the brains of patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

High expression of apolipoprotein E mRNA in the brains with sporadic Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2803%2900361-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0306-4522(03)00361-0

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

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