(Q44576317)

4 December 2017

Caspase activation increases beta-amyloid generation independently of caspase cleavage of the beta-amyloid precursor protein (APP). (English)

1 reference

4 December 2017

3

Rudolph E Tanzi

1 reference

4 December 2017

1

Giuseppina Tesco

1 reference

4 December 2017

Young Ho Koh

2

1 reference

PubMed ID

12960154

4 December 2017

language of work or name

English

0 references

publication date

5 September 2003

1 reference

Journal of Biological Chemistry

4 December 2017

1 reference

4 December 2017

278

1 reference

4 December 2017

46074-46080

1 reference

4 December 2017

46

1 reference

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

4 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

The caspase family of cysteine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

Many cuts to ruin: a comprehensive update of caspase substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

Alternative, non-secretase processing of Alzheimer's beta-amyloid precursor protein during apoptosis by caspase-6 and -8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

Increased amyloidogenic secretion in cerebellar granule cells undergoing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

Abrogation of the presenilin 1/beta-catenin interaction and preservation of the heterodimeric presenilin 1 complex following caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

Intracellular generation and accumulation of amyloid beta-peptide terminating at amino acid 42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

Presenilin 1 regulates pharmacologically distinct gamma -secretase activities. Implications for the role of presenilin in gamma -secretase cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

Presenilins are not required for A beta 42 production in the early secretory pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

Structural neurology: are seeds at the root of neuronal degeneration?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

The role of cerebral ischemia in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

The amyloidogenic pathway of amyloid precursor protein (APP) is independent of its cleavage by caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

A distinct ER/IC gamma-secretase competes with the proteasome for cleavage of APP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

The carboxyl termini of beta-amyloid peptides 1-40 and 1-42 are generated by distinct gamma-secretase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307809200

21 January 2018

Identifiers

DOI

10.1074/JBC.M307809200

1 reference

4 December 2017

1 reference

PubMed ID

12960154