(Q44590854)

English

Distortion of the Catalytic Domain of Tissue-type Plasminogen Activator by Plasminogen Activator Inhibitor-1 Coincides with the Formation of Stable Serpin-Proteinase Complexes

scientific article published on September 18, 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Distortion of the catalytic domain of tissue-type plasminogen activator by plasminogen activator inhibitor-1 coincides with the formation of stable serpin-proteinase complexes (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Distortion of the Catalytic Domain of Tissue-type Plasminogen Activator by Plasminogen Activator Inhibitor-1 Coincides with the Formation of Stable Serpin-Proteinase Complexes (English)

1 reference

10.1074/JBC.M306184200

https://api.crossref.org/works/10.1074/JBC.M306184200

12 March 2024

1 reference

based on heuristic

inferred from title

1 reference

10.1074/JBC.M306184200

https://api.crossref.org/works/10.1074/JBC.M306184200

12 March 2024

1 reference

10.1074/JBC.M306184200

https://api.crossref.org/works/10.1074/JBC.M306184200

12 March 2024

author name string

Michel J. Perron

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500731

12 March 2024

Grant E. Blouse

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500731

12 March 2024

Joseph D. Shore

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500731

12 March 2024

language of work or name

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publication date

18 September 2003

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

full work available at URL

http://www.jbc.org/article/S0021925820758540/pdf

Portable Document Format

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500731

12 March 2024

https://api.elsevier.com/content/article/PII:S0021925820758540?httpAccept=text/xml

1 reference

10.1074/JBC.M306184200

https://api.crossref.org/works/10.1074/JBC.M306184200

12 March 2024

https://api.elsevier.com/content/article/PII:S0021925820758540?httpAccept=text/plain

1 reference

10.1074/JBC.M306184200

https://api.crossref.org/works/10.1074/JBC.M306184200

12 March 2024

https://syndication.highwire.org/content/doi/10.1074/jbc.M306184200

1 reference

10.1074/JBC.M306184200

https://api.crossref.org/works/10.1074/JBC.M306184200

12 March 2024

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

278

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

48

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

48197-48203

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

The molecular basis for anti-proteolytic and non-proteolytic functions of plasminogen activator inhibitor type-1: roles of the reactive centre loop, the shutter region, the flexible joint region and the small serpin fragment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Divining the serpin inhibition mechanism: a suicide substrate 'springe'?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Structure of a serpin-protease complex shows inhibition by deformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Intrinsic fluorescence changes and rapid kinetics of proteinase deformation during serpin inhibition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Insight into the mechanism of serpin-proteinase inhibition from 2D [1H-15N] NMR studies of the 69 kDa alpha 1-proteinase inhibitor Pittsburgh-trypsin covalent complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Effects of serpin binding on the target proteinase: global stabilization, localized increased structural flexibility, and conserved hydrogen bonding at the active site.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Conformational change in elastase following complexation with alpha1-proteinase inhibitor: a CD investigation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

A serpin-induced extensive proteolytic susceptibility of urokinase-type plasminogen activator implicates distortion of the proteinase substrate-binding pocket and oxyanion hole in the serpin inhibitory mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

In vivo footprinting of the interaction of proteins with DNA and RNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Incorporation of tryptophan analogues into staphylococcal nuclease, its V66W mutant, and Delta 137-149 fragment: spectroscopic studies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

A concerted structural transition in the plasminogen activator inhibitor-1 mechanism of inhibition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Dynamic structural and functional relationships in recombinant plasminogen activator inhibitor-1 (rPAI-1).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Determination of the rate constant of enzyme modification by measuring the substrate reaction in the presence of the modifier.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Alpha 1-proteinase inhibitor variant T345R. Influence of P14 residue on substrate and inhibitory pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

The 2.3 A crystal structure of the catalytic domain of recombinant two-chain human tissue-type plasminogen activator

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

The F-helix of serpins plays an essential, active role in the proteinase inhibition mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

The pH dependence of serpin-proteinase complex dissociation reveals a mechanism of complex stabilization involving inactive and active conformational states of the proteinase which are perturbable by calcium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Thrombin is a Na(+)-activated enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

The variable region-1 from tissue-type plasminogen activator confers specificity for plasminogen activator inhibitor-1 to thrombin by facilitating catalysis: release of a kinetic block by a heterologous protein surface loop

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Mutation of the Highly Conserved Tryptophan in the Serpin Breach Region Alters the Inhibitory Mechanism of Plasminogen Activator Inhibitor-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Distortion of the active site of chymotrypsin complexed with a serpin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Inhibitory mechanism of serpins: loop insertion forces acylation of plasminogen activator by plasminogen activator inhibitor-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Substrate specificity of tissue type plasminogen activator. Characterization of the fibrin independent specificity of t-PA for plasminogen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Resolution of Michaelis complex, acylation, and conformational change steps in the reactions of the serpin, plasminogen activator inhibitor-1, with tissue plasminogen activator and trypsin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Atomic Mutations at the Single Tryptophan Residue of Human Recombinant Annexin V: Effects on Structure, Stability, and Activity‡

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

The plasminogen activator inhibitor-1 binding site in the kringle-2 domain of tissue-type plasminogen activator

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Stopped flow fluorescence energy transfer measurement of the rate constants describing the reversible formation and the irreversible rearrangement of the elastase-alpha1-proteinase inhibitor complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306184200

21 January 2018

Enhancement of protein spectra with tryptophan analogs: fluorescence spectroscopy of protein-protein and protein-nucleic acid interactions

10

1 reference

10.1074/JBC.M306184200

https://api.crossref.org/works/10.1074/JBC.M306184200

12 March 2024

Biosynthetic incorporation of tryptophan analogues into staphylococcal nuclease: effect of 5-hydroxytryptophan and 7-azatryptophan on structure and stability

11

1 reference

10.1074/JBC.M306184200

https://api.crossref.org/works/10.1074/JBC.M306184200

12 March 2024

Purification of human plasminogen activator inhibitor (PAI-1) from Escherichia coli and separation of its active and latent forms by hydrophobic interaction chromatography

16

1 reference

10.1074/JBC.M306184200

https://api.crossref.org/works/10.1074/JBC.M306184200

12 March 2024

Functional properties of the recombinant kringle-2 domain of tissue plasminogen activator produced in Escherichia coli

25

1 reference

10.1074/JBC.M306184200

https://api.crossref.org/works/10.1074/JBC.M306184200

12 March 2024

Identifiers

10.1074/JBC.M306184200

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

ResearchGate publication ID

0 references

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