(Q44612699)

4 December 2017

title

The concerted signaling of ERK1/2 and JNKs is essential for PC12 cell neuritogenesis and converges at the level of target proteins (English)

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4 December 2017

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https://api.crossref.org/works/10.1016/S1044-7431(03)00126-X

20 March 2024

author name string

Vicki Waetzig

1

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4 December 2017

Thomas Herdegen

2

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4 December 2017

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14550783

20 March 2024

publication date

1 September 2003

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full work available at URL

4 December 2017

https://api.elsevier.com/content/article/PII:S104474310300126X?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S1044-7431(03)00126-X

https://api.elsevier.com/content/article/PII:S104474310300126X?httpAccept=text/plain

20 March 2024

1 reference

https://api.crossref.org/works/10.1016/S1044-7431(03)00126-X

Molecular and Cellular Neuroscience

20 March 2024

published in

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4 December 2017

volume

24

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4 December 2017

issue

1

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4 December 2017

page(s)

238-249

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The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

4 December 2017

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Nerve growth factor in combination with second messenger analogues causes neuronal differentiation of PC12 cells expressing a dominant inhibitory Ras protein without inducing activation of extracellular signal-regulated kinases

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Differential feedback regulation of the MAPK cascade underlies the quantitative differences in EGF and NGF signalling in PC12 cells

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Insulin regulates MAP kinase phosphatase-1 induction in Hirc B cells via activation of both extracellular signal-regulated kinase (ERK) and c-Jun-N-terminal kinase (JNK).

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7 January 2021

Induction of the mitogen-activated protein kinase phosphatase MKP3 by nerve growth factor in differentiating PC12

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Parallel signal processing among mammalian MAPKs

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Fibroblast growth factor receptors participate in the control of mitogen-activated protein kinase activity during nerve growth factor-induced neuronal differentiation of PC12 cells

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7 January 2021

Dual roles for c-Jun N-terminal kinase in developmental and stress responses in cerebellar granule neurons.

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c-Jun N-terminal protein kinase (JNK) 2/3 is specifically activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons.

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Abrogation of nerve growth factor-induced terminal differentiation by ret oncogene involves perturbation of nuclear translocation of ERK

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7 January 2021

c-Jun promotes neurite outgrowth and survival in PC12 cells

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7 January 2021

Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons.

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Activation of c-Jun N-terminal kinase 1 by UV irradiation is inhibited by wortmannin without affecting c-iun expression

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7 January 2021

Aberrant stress-induced phosphorylation of perikaryal neurofilaments

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7 January 2021

Physiological stress and nerve growth factor treatment regulate stress-activated protein kinase activity in PC12 cells

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7 January 2021

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

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7 January 2021

Nerve growth factor- and epidermal growth factor-regulated gene transcription in PC12 pheochromocytoma and INS-1 insulinoma cells

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7 January 2021

c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

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7 January 2021

Cyclic AMP-induced neuronal differentiation via activation of p38 mitogen-activated protein kinase

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Expression of activating transcription factor-2, serum response factor and cAMP/Ca response element binding protein in the adult rat brain following generalized seizures, nerve fibre lesion and ultraviolet irradiation

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7 January 2021

Mitogen-activated protein kinase phosphatases inactivate stress-activated protein kinase pathways in vivo

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7 January 2021

Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

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7 January 2021

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

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7 January 2021

Neurotrophin signal transduction in the nervous system

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7 January 2021

Up-regulation of ERK (MAP kinase) and MEK (MAP kinase kinase) transcription after rat facial nerve transection

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7 January 2021

Expression of a constitutively active phosphatidylinositol 3-kinase induces process formation in rat PC12 cells. Use of Cre/loxP recombination system

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7 January 2021

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

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7 January 2021

Differential regulation of c-Jun by ERK and JNK during PC12 cell differentiation.

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7 January 2021

Molecular cloning of a gene sequence regulated by nerve growth factor

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7 January 2021

A dominant negative inhibitor of the Egr family of transcription regulatory factors suppresses cerebellar granule cell apoptosis by blocking c-Jun activation.

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7 January 2021

Activation of mitogen-activated protein kinases (Erk1 and Erk2) cascade results in phosphorylation of NF-M tail domains in transfected NIH 3T3 cells

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7 January 2021

Activation of extracellular signal-regulated kinases 1 and 2 by depolarization stimulates tyrosine hydroxylase phosphorylation and dopamine synthesis in rat brain

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7 January 2021

Different signaling pathways mediate regenerative versus developmental sensory axon growth.

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7 January 2021

Rho GTPases in neuronal morphogenesis

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7 January 2021

Motoneuron apoptosis is blocked by CEP-1347 (KT 7515), a novel inhibitor of the JNK signaling pathway

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7 January 2021

Activity and expression of JNK1, p38 and ERK kinases, c-Jun N-terminal phosphorylation, and c-jun promoter binding in the adult rat brain following kainate-induced seizures

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7 January 2021

Fatal shift of signal transduction is an integral part of neuronal differentiation: JNKs realize TNFalpha-mediated apoptosis in neuronlike, but not naive, PC12 cells.

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7 January 2021

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

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7 January 2021

Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells

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7 January 2021

c-Jun N-terminal kinase-3 (JNK3)/stress-activated protein kinase-beta (SAPKbeta) binds and phosphorylates the neuronal microtubule regulator SCG10

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7 January 2021

Distinct neurite outgrowth signaling pathways converge on ERK activation

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7 January 2021

PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity

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7 January 2021

Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice

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7 January 2021

Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors

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7 January 2021

Cell cycle-specific action of nerve growth factor in PC12 cells: differentiation without proliferation

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7 January 2021

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

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7 January 2021

MPTP activates c-Jun NH(2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo

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7 January 2021

The MAPK signaling cascade

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7 January 2021

Apoptosis signal-regulating kinase 1 (ASK1) induces neuronal differentiation and survival of PC12 cells

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7 January 2021

Activation of the protein kinase p38 in the spindle assembly checkpoint and mitotic arrest.

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7 January 2021

A single c-Jun N-terminal kinase isoform (JNK3-p54) is an effector in both neuronal differentiation and cell death

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7 January 2021

Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways.

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7 January 2021

Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human

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7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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7 January 2021

NGF regulates the PC12 cell cycle machinery through specific inhibition of the Cdk kinases and induction of cyclin D1

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7 January 2021

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

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7 January 2021

Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1.

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7 January 2021

Specific activation of a c-Jun NH2-terminal kinase isoform and induction of neurite outgrowth in PC-12 cells by staurosporine

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7 January 2021

Collaboration of JNKs and ERKs in nerve growth factor regulation of the neurofilament light chain promoter in PC12 cells

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7 January 2021

Signal transduction by the c-Jun N-terminal kinase

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The ras suppressor, RSU-1, enhances nerve growth factor-induced differentiation of PC12 cells and induces p21CIP expression

20 March 2024

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Translocation of MAP (Erk-1 and -2) kinases to cell nuclei and activation of c-fos gene during healing of experimental gastric ulcers

20 March 2024

58

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20 March 2024

Identifiers

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4 December 2017

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