(Q44660977)

English

SU1498, an inhibitor of vascular endothelial growth factor receptor 2, causes accumulation of phosphorylated ERK kinases and inhibits their activity in vivo and in vitro

scientific article published on 18 November 2003

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

SU1498, an inhibitor of vascular endothelial growth factor receptor 2, causes accumulation of phosphorylated ERK kinases and inhibits their activity in vivo and in vitro (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

0 references

phosphorylation

0 references

1 reference

ChEBI release 2020-05-28

author name string

George Boguslawski

1

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Patrick W McGlynn

2

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Kevin A Harvey

3

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

A Thomas Kovala

4

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

language of work or name

0 references

publication date

18 November 2003

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

279

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

5716-5724

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Mechanisms of angiogenesis and arteriogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Sphingosine 1-phosphate, a key cell signaling molecule

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Migration of vascular smooth muscle cells induced by sphingosine 1-phosphate and related lipids: potential role in the angiogenic response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Tethering of the platelet-derived growth factor beta receptor to G-protein-coupled receptors. A novel platform for integrative signaling by these receptor classes in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Oncogenic kinase signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

New insights into the control of MAP kinase pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

ADP-ribosylation factors: a family of approximately 20-kDa guanine nucleotide-binding proteins that activate cholera toxin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

G proteins: transducers of receptor-generated signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

A synthetic inhibitor of the mitogen-activated protein kinase cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Tyrphostins. II. Heterocyclic and .alpha.-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

ERK and RhoA differentially regulate pseudopodia growth and retraction during chemotaxis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Signal transduction by the chemokine receptor CXCR3: activation of Ras/ERK, Src, and phosphatidylinositol 3-kinase/Akt controls cell migration and proliferation in human vascular pericytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Differential regulation of sphingosine-1-phosphate- and VEGF-induced endothelial cell chemotaxis. Involvement of G(ialpha2)-linked Rho kinase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Leptin induces endothelial cell migration through Akt, which is inhibited by PPARgamma-ligands

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Cooperativity between the Ras-ERK and Rho-Rho kinase pathways in urokinase-type plasminogen activator-stimulated cell migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

The role of p42/44 MAPK and protein kinase B in connective tissue growth factor induced extracellular matrix protein production, cell migration, and actin cytoskeletal rearrangement in human mesangial cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Phosphorylation and regulation of Raf by Akt (protein kinase B)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Interplay between integrins and FLK-1 in shear stress-induced signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Blockade of platelet-derived growth factor receptor-beta pathway induces apoptosis of vascular endothelial cells and disrupts glomerular capillary formation in neonatal mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Time- and cell type-specific induction of platelet-derived growth factor receptor-beta during cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

p38 and ERK1/2 coordinate cellular migration and proliferation in epithelial wound healing: evidence of cross-talk activation between MAP kinase cascades

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Differential regulation of Raf-1 and B-Raf and Ras-dependent activation of mitogen-activated protein kinase by cyclic AMP in PC12 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Mechanisms of regulating the Raf kinase family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Examining the mechanism of Erk nuclear translocation using green fluorescent protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Nuclear localization and regulation of erk- and rsk-encoded protein kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Cytoplasmic aggregates of phosphorylated extracellular signal-regulated protein kinases in Lewy body diseases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Differential interaction of the tyrosine phosphatases PTP-SL, STEP and HePTP with the mitogen-activated protein kinases ERK1/2 and p38alpha is determined by a kinase specificity sequence and influenced by reducing agents

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Interaction of mitogen-activated protein kinases with the kinase interaction motif of the tyrosine phosphatase PTP-SL provides substrate specificity and retains ERK2 in the cytoplasm

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Inhibition of T cell signaling by mitogen-activated protein kinase-targeted hematopoietic tyrosine phosphatase (HePTP)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Extracellular signals and scores of phosphatases: all roads lead to MAP kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Inactivation of Dual-Specificity Phosphatases Is Involved in the Regulation of Extracellular Signal-Regulated Kinases by Heat Shock and Hsp72

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Specificity and mechanism of action of some commonly used protein kinase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Kinase inhibitors: not just for kinases anymore

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Tissue localization of beta receptors for platelet-derived growth factor and platelet-derived growth factor B chain during wound repair in humans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Human microvascular endothelial cells express receptors for platelet-derived growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Two clusters of residues at the docking groove of mitogen-activated protein kinases differentially mediate their functional interaction with the tyrosine phosphatases PTP-SL and STEP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

The mouse B-raf gene encodes multiple protein isoforms with tissue-specific expression.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Follicle-stimulating hormone activates extracellular signal-regulated kinase but not extracellular signal-regulated kinase kinase through a 100-kDa phosphotyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308625200

21 January 2018

Identifiers

10.1074/JBC.M308625200

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q44660977&oldid=2031065293"