(Q44674004)

5 December 2017

title

Conserved sequence motifs and the structure of the mTOR kinase domain (English)

1 reference

5 December 2017

Evelyn Sauer

1

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5 December 2017

Stefan Imseng

series ordinal

2

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5 December 2017

Timm Maier

series ordinal

3

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5 December 2017

Michael N Hall

series ordinal

4

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5 December 2017

publication date

1 August 2013

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Biochemical Society Transactions

5 December 2017

published in

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5 December 2017

volume

41

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5 December 2017

issue

4

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5 December 2017

page(s)

889-895

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Activation loop phosphorylation and catalysis in protein kinases: is there functional evidence for the autoinhibitor model?

5 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Mechanisms of specificity in protein phosphorylation

21 January 2018

1 reference

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The protein kinase complement of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Kinetic and catalytic mechanisms of protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

The structural basis for control of eukaryotic protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

mTOR signaling in growth control and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Rapamycin passes the torch: a new generation of mTOR inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

mTOR in aging, metabolism, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

mTOR-dependent cell survival mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Activation of mTORC2 by association with the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

AGC protein kinases: from structural mechanism of regulation to allosteric drug development for the treatment of human diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Identification of a conserved motif required for mTOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Molecular organization of target of rapamycin complex 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Identification of Protor as a novel Rictor-binding component of mTOR complex-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Emerging common themes in regulation of PIKKs and PI3Ks

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Insights into the domain and repeat architecture of target of rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

HEAT repeats in the Huntington's disease protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

The tetratricopeptide repeat: a structural motif mediating protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Protein repeats: structures, functions, and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

mTOR kinase structure, mechanism and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Activating mutations in TOR are in similar structures as oncogenic mutations in PI3KCalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Discovery of potent and selective inhibitors of the mammalian target of rapamycin (mTOR) kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Discovery of 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a potent, selective, and orally available mammalian target of rapamycin (mTOR) inhibitor for treatment of cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

The FATC domains of PIKK proteins are functionally equivalent and participate in the Tip60-dependent activation of DNA-PKcs and ATM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Protein structure prediction and structural genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Comparative protein structure modeling by iterative alignment, model building and model assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Infrastructure for the life sciences: design and implementation of the UniProt website

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

MUSCLE: a multiple sequence alignment method with reduced time and space complexity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

ESPript/ENDscript: Extracting and rendering sequence and 3D information from atomic structures of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130113

21 January 2018

Identifiers

DOI

10.1042/BST20130113

1 reference

release_qqpp2jnrhba4xbd6d3gsqsjf4u

5 December 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qqpp2jnrhba4xbd6d3gsqsjf4u

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference