(Q44697049)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848438%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

title

Increased radiation sensitivity of head and neck squamous cell carcinoma with sphingosine kinase 1 inhibition (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848438%20AND%20SRC:MED&resulttype=core&format=json

head and neck squamous cell carcinoma

14 February 2020

main subject

0 references

author

Steven B Chinn

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848438%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

author name string

Uttam K Sinha

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848438%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Victor J Schorn

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848438%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Christian Hochstim

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848438%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Sutao Zhu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848438%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Rizwan Masood

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848438%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

publication date

1 February 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848438%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848438%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848438%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848438%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

page(s)

178-188

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848438%20AND%20SRC:MED&resulttype=core&format=json

Global cancer statistics, 2002

14 February 2020

cites work

1 reference

21 January 2018

Cancer statistics, 2008

1 reference

21 January 2018

1 reference

Mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radiotherapy with or without chemotherapy: a systematic literature review

21 January 2018

1 reference

Prevention and treatment of dysphagia and aspiration after chemoradiation for head and neck cancer

21 January 2018

1 reference

Biologically active sphingolipids in cancer pathogenesis and treatment

21 January 2018

1 reference

Principles of bioactive lipid signalling: lessons from sphingolipids

21 January 2018

1 reference

Sphingosine-1-phosphate: an enigmatic signalling lipid

21 January 2018

1 reference

Sphingosine 1-phosphate and ceramide 1-phosphate: expanding roles in cell signaling

21 January 2018

1 reference

Sphingosine 1-phosphate induces angiogenesis: its angiogenic action and signaling mechanism in human umbilical vein endothelial cells

21 January 2018

1 reference

Sphingosine kinase as an oncogene: autocrine sphingosine 1-phosphate modulates ML-1 thyroid carcinoma cell migration by a mechanism dependent on protein kinase C-alpha and ERK1/2.

21 January 2018

1 reference

S1P differentially regulates migration of human ovarian cancer and human ovarian surface epithelial cells

21 January 2018

1 reference

Regulation of vascular permeability by sphingosine 1-phosphate

21 January 2018

1 reference

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

21 January 2018

1 reference

Molecular cloning and functional characterization of murine sphingosine kinase

21 January 2018

1 reference

Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response.

21 January 2018

1 reference

Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival.

21 January 2018

1 reference

Functions of the multifaceted family of sphingosine kinases and some close relatives

21 January 2018

1 reference

Role for sphingosine kinase 1 in colon carcinogenesis.

21 January 2018

1 reference

Sphingosine kinase-1 expression correlates with poor survival of patients with glioblastoma multiforme: roles of sphingosine kinase isoforms in growth of glioblastoma cell lines

21 January 2018

1 reference

Clinical significance of sphingosine kinase-1 expression in human astrocytomas progression and overall patient survival

21 January 2018

1 reference

Sphingosine kinase 1 is associated with gastric cancer progression and poor survival of patients

21 January 2018

1 reference

The role of sphingosine kinase 1 in cancer: oncogene or non-oncogene addiction?

21 January 2018

1 reference

An oncogenic role of sphingosine kinase

21 January 2018

1 reference

Radiation and ceramide-induced apoptosis

21 January 2018

1 reference

Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C. elegans

21 January 2018

1 reference

Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy

21 January 2018

1 reference

Sphingosine 1-phosphate preserves fertility in irradiated female mice without propagating genomic damage in offspring

21 January 2018

1 reference

Down-regulation of sphingosine kinase-1 by DNA damage: dependence on proteases and p53.

21 January 2018

1 reference

Acid ceramidase upregulation in prostate cancer cells confers resistance to radiation: AC inhibition, a potential radiosensitizer

21 January 2018

1 reference

Sphingosine kinase-1 mediates BCR/ABL-induced upregulation of Mcl-1 in chronic myeloid leukemia cells

21 January 2018

1 reference

Sphingosine kinase-1 is a downstream regulator of imatinib-induced apoptosis in chronic myeloid leukemia cells

21 January 2018

1 reference

Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors.

21 January 2018

1 reference

EphB4 provides survival advantage to squamous cell carcinoma of the head and neck

21 January 2018

1 reference

Emerging perspectives in epidermal growth factor receptor targeting in head and neck cancer

21 January 2018

1 reference

Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): attenuation of C(18)-ceramide in HNSCC tumors correlates with lymphovascular invasion and nodal metastasis

21 January 2018

1 reference

Enhancement of radiosensitivity by combined ceramide and dimethylsphingosine treatment in lung cancer cells

21 January 2018

1 reference

Overexpression of sphingosine-1-phosphate lyase or inhibition of sphingosine kinase in Dictyostelium discoideum results in a selective increase in sensitivity to platinum-based chemotherapy drugs

21 January 2018

1 reference

Overcoming MDR-associated chemoresistance in HL-60 acute myeloid leukemia cells by targeting sphingosine kinase-1.

21 January 2018

1 reference

Chemosensitizing effects of sphingosine kinase-1 inhibition in prostate cancer cell and animal models.

21 January 2018

1 reference

Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: modulation of sphingolipid levels and the induction of apoptosis.

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Downregulating sphingosine kinase-1 for cancer therapy

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Sphingosine kinase 1 expression is regulated by signaling through PI3K, AKT2, and mTOR in human coronary artery smooth muscle cells

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/HED.21418

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848438%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference