(Q44945431)

7 December 2017

title

Phytosphingosine derivatives ameliorate skin inflammation by inhibiting NF-κB and JAK/STAT signaling in keratinocytes and mice (English)

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7 December 2017

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Byung-Hak Kim

1

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7 December 2017

Ji Min Lee

2

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7 December 2017

Yong-Gyu Jung

3

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7 December 2017

Sanghee Kim

4

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7 December 2017

Tae-Yoon Kim

5

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7 December 2017

language of work or name

English

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publication date

31 October 2013

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Journal of Investigative Dermatology

7 December 2017

published in

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7 December 2017

volume

134

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7 December 2017

issue

4

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7 December 2017

page(s)

1023-1032

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https://scigraph.springernature.com/pub.10.1038/jid.2013.453

7 December 2017

exact match

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cites work

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DMF inhibits PDGF-BB induced airway smooth muscle cell proliferation through induction of heme-oxygenase-1.

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The mitogen-activated protein kinases p38 and ERK1/2 are increased in lesional psoriatic skin

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Topical application of a novel immunomodulatory peptide, RDP58, reduces skin inflammation in the phorbol ester-induced dermatitis model

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12 December 2020

Anti-scratching behavioral effects of N-stearoyl-phytosphingosine and 4-hydroxysphinganine in mice

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12 December 2020

NF-kappaB signaling pathway and its therapeutic implications in human diseases

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In vitro and in vivo evaluation of N,N,N-trimethylphytosphingosine-iodide (TMP) in liposomes for the treatment of angiogenesis and metastasis.

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The effect of dietary phytosphingosine on cholesterol levels and insulin sensitivity in subjects with the metabolic syndrome.

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STAT1 as a novel therapeutical target in pro-atherogenic signal integration of IFNγ, TLR4 and IL-6 in vascular disease

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12 December 2020

Fumaric Acid and its esters: an emerging treatment for multiple sclerosis

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Kurarinone regulates immune responses through regulation of the JAK/STAT and TCR-mediated signaling pathways.

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Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells

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12 December 2020

IL-23-mediated psoriasis-like epidermal hyperplasia is dependent on IL-17A

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12 December 2020

Lipids and skin barrier function--a clinical perspective

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12 December 2020

An update of the defensive barrier function of skin

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12 December 2020

Novel sphingolipid derivatives promote keratinocyte differentiation

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12 December 2020

Ceramides and skin function.

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12 December 2020

NKT cell stimulation with α-galactosylceramide results in a block of Th17 differentiation after intranasal immunization in mice

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What is the 'true' function of skin?

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12 December 2020

Anti-microbial and -inflammatory activity and efficacy of phytosphingosine: an in vitro and in vivo study addressing acne vulgaris

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The role of signal transducers and activators of transcription in T inflammatory bowel diseases

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Loss of extracellular superoxide dismutase induces severe IL-23-mediated skin inflammation in mice

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12 December 2020

Th17 cells: biology, pathogenesis of autoimmune and inflammatory diseases, and therapeutic strategies

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12 December 2020

Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus

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12 December 2020

Differential regulation of cyclooxygenase-2 expression by phytosphingosine derivatives, NAPS and TAPS, and its role in the NAPS or TAPS-mediated apoptosis

1 reference

12 December 2020

Interleukin-1 alpha mediates phorbol ester-induced inflammation and epidermal hyperplasia.

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12 December 2020

Epidermal CCR6+ γδ T cells are major producers of IL-22 and IL-17 in a murine model of psoriasiform dermatitis

1 reference

12 December 2020

The nuclear factor NF-kappaB pathway in inflammation

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12 December 2020

Suppression of extracellular signal-related kinase and activation of p38 MAPK are two critical events leading to caspase-8- and mitochondria-mediated cell death in phytosphingosine-treated human cancer cells

1 reference

12 December 2020

The roles of the classical and alternative nuclear factor-kappaB pathways: potential implications for autoimmunity and rheumatoid arthritis

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12 December 2020

Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

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12 December 2020

Potentiation of UVB-induced apoptosis by novel phytosphingosine derivative, tetraacetyl phytosphingosine in HaCaT cell and mouse skin

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12 December 2020

Dimethylfumarate inhibits microglial and astrocytic inflammation by suppressing the synthesis of nitric oxide, IL-1beta, TNF-alpha and IL-6 in an in-vitro model of brain inflammation

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12 December 2020

Role of T Cells in -Galactosylceramide-Mediated Immunity

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12 December 2020

Biochemistry of human skin--our brain on the outside

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12 December 2020

Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria.

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12 December 2020

Phytosphingosine stimulates the differentiation of human keratinocytes and inhibits TPA-induced inflammatory epidermal hyperplasia in hairless mouse skin

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12 December 2020

Fumaric acid esters as a suitable first-line treatment for severe psoriasis: an Irish experience

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12 December 2020

Tetraacetyl phytosphingosine-induced caspase activation and apoptosis occur through G2 arrest in human keratinocyte HaCaT cells

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Embelin reduces cutaneous TNF-α level and ameliorates skin edema in acute and chronic model of skin inflammation in mice

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12 December 2020

Th17 cytokines stimulate CCL20 expression in keratinocytes in vitro and in vivo: implications for psoriasis pathogenesis

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12 December 2020

Regulation of skin inflammation and angiogenesis by EC-SOD via HIF-1α and NF-κB pathways.

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12 December 2020

Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL)

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12 December 2020

Epidermal surface lipids

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12 December 2020

Chemokine receptors in the pathogenesis and therapy of psoriasis

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12 December 2020

Regulation of JAK-STAT signalling in the immune system

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12 December 2020

The Th17/IL-23 Axis and Natural Immunity in Psoriatic Arthritis

1 reference

12 December 2020

Therapy of noninfectious granulomatous skin diseases with fumaric acid esters

1 reference

12 December 2020

The outer frontier: the importance of lipid metabolism in the skin

1 reference

12 December 2020

Differential expression of phosphorylated extracellular signal-regulated kinase 1/2, phosphorylated p38 mitogen-activated protein kinase and nuclear factor-kappaB p105/p50 in chronic inflammatory skin diseases

1 reference

12 December 2020

Innate Immunity in the Skin: How Keratinocytes Fight Against Pathogens

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FJID.2013.453

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/JID.2013.453

1 reference

7 December 2017

1 reference