(Q44947237)

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Cruciferous nutraceutical 3H-1,2-dithiole-3-thione protects human primary astrocytes against neurocytotoxicity elicited by MPTP, MPP(+), 6-OHDA, HNE and acrolein

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Europe PubMed Central

PubMed publication ID

7 December 2017

Cruciferous nutraceutical 3H-1,2-dithiole-3-thione protects human primary astrocytes against neurocytotoxicity elicited by MPTP, MPP(+), 6-OHDA, HNE and acrolein (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

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1 reference

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author name string

Zhenquan Jia

1

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Hong Zhu

2

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Yunbo Li

3

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Hara P Misra

4

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Europe PubMed Central

PubMed publication ID

7 December 2017

language of work or name

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1 May 2009

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Europe PubMed Central

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7 December 2017

Neurochemical Research

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Europe PubMed Central

PubMed publication ID

7 December 2017

34

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Europe PubMed Central

PubMed publication ID

7 December 2017

11

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Europe PubMed Central

PubMed publication ID

7 December 2017

1924-1934

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Europe PubMed Central

PubMed publication ID

7 December 2017

Oxidative stress and nitration in neurodegeneration: cause, effect, or association?

1 reference

https://api.crossref.org/works/10.1007%2FS11064-009-9978-8

21 January 2018

Conjugates of catecholamines with cysteine and GSH in Parkinson's disease: possible mechanisms of formation involving reactive oxygen species.

1 reference

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Prevention of 1-methyl-4-phenylpyridinium- and 6-hydroxydopamine-induced nitration of tyrosine hydroxylase and neurotoxicity by EUK-134, a superoxide dismutase and catalase mimetic, in cultured dopaminergic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

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Viewpoint: mechanisms of action and therapeutic potential of neurohormetic phytochemicals

1 reference

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12 December 2020

based on heuristic

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The neurotoxicity of glutamate, dopamine, iron and reactive oxygen species: functional interrelationships in health and disease: a review-discussion

1 reference

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12 December 2020

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Protective effects of moderate hypothermia after neonatal hypoxia-ischemia: short- and long-term outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

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Food as medicine: potential therapeutic tendencies of plant derived polyphenolic compounds.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

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Metabolism and functions of glutathione in brain.

1 reference

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based on heuristic

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Generation of reactive oxygen species during the monoamine oxidase-catalyzed oxidation of the neurotoxicant, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

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Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

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Alpha-tocopherol and beta-carotene do not protect marmosets against the dopaminergic neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of cellular glutathione and glutathione S-transferase by 3H-1,2-dithiole-3-thione in rat aortic smooth muscle A10 cells: protection against acrolein-induced toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial toxins in models of neurodegenerative diseases. I: In vivo brain hydroxyl radical production during systemic MPTP treatment or following microdialysis infusion of methylpyridinium or azide ions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

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Potent upregulation of glutathione and NAD(P)H:quinone oxidoreductase 1 by alpha-lipoic acid in human neuroblastoma SH-SY5Y cells: protection against neurotoxicant-elicited cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione: an overview of biosynthesis and modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nrf2 controls bone marrow stromal cell susceptibility to oxidative and electrophilic stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide radical production during the autoxidation of 1-methyl-4-phenyl-2,3-dihydropyridinium perchlorate

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of endogenous glutathione system by 3H-1,2-dithiole-3-thione in pancreatic RINm5F beta-cells as a novel strategy for protecting against oxidative beta-cell injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of endogenous glutathione levels on 6-hydroxydopamine-induced apoptotic neuronal cell death in human neuroblastoma SK-N-SH cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stress, aging, and brain oxidative damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular effects of acrolein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione S-transferases. The first enzymatic step in mercapturic acid formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkinson's disease as multifactorial oxidative neurodegeneration: implications for integrative management.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress and antioxidant therapy in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased striatal lipid peroxidation after intracerebroventricular MPP+ administration to mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocyte-mediated enhancement of neuronal survival is abolished by glutathione deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione and catalase provide overlapping defenses for protection against hydrogen peroxide in the yeast Saccharomyces cerevisiae.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidants and phase 2 enzymes in cardiomyocytes: Chemical inducibility and chemoprotection against oxidant and simulated ischemia-reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrates for neural metabolism of xenobiotics in adult and developing brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein-bound acrolein: a novel marker of oxidative stress in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of astrocytes in MPTP metabolism and toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of antioxidants on L-glutamate and N-methyl-4-phenylpyridinium ion induced-neurotoxicity in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glutathione system of peroxide detoxification is less efficient in neurons than in astroglial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of NQO1 protects human SK-N-MC neuroblastoma cells against dopamine-induced cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular bases of Alzheimer's disease and other neurodegenerative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytes protect neurons from nitric oxide toxicity by a glutathione-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NAD(P)H:quinone oxidoreductase 1: role as a superoxide scavenger

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(E)-4-hydroxy-2-nonenal may be involved in the pathogenesis of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased brain levels of 4-hydroxy-2-nonenal glutathione conjugates in severe Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Automated assays for superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron-mediated bioactivation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in glial cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidant compounds protect dopamine neurons from death due to oxidative stress in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MPP+ and MPDP+ induced oxygen radical formation with mitochondrial enzymes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodegeneration or neuroprotection: the pivotal role of astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic administration of antioxidants does not protect mice against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP).

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging, energy, and oxidative stress in neurodegenerative diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Etiology and pathogenesis of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interrelationships between astrocyte function, oxidative stress and antioxidant status within the central nervous system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DATATOP: a decade of neuroprotective inquiry. Parkinson Study Group. Deprenyl And Tocopherol Antioxidative Therapy Of Parkinsonism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of antioxidants in prophylaxis and therapy: A pharmaceutical perspective

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A fluorometric method for determination of oxidized and reduced glutathione in tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fruit and vegetable intake in relation to risk of ischemic stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinone reductases multitasking in the metabolic world

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acrolein, a product of lipid peroxidation, inhibits glucose and glutamate uptake in primary neuronal cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain iron pathways and their relevance to Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: protection against reactive oxygen and nitrogen species-induced cell injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potent induction of total cellular GSH and NQO1 as well as mitochondrial GSH by 3H-1,2-dithiole-3-thione in SH-SY5Y neuroblastoma cells and primary human neurons: protection against neurocytotoxicity elicited by dopamine, 6-hydroxydopamine, 4-hydrox

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assays of glutathione peroxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free radicals as mediators of tissue injury and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary fatty acids and the risk of Parkinson disease: the Rotterdam study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine- and L-beta-3,4-dihydroxyphenylalanine hydrochloride (L-Dopa)-induced cytotoxicity towards catecholaminergic neuroblastoma SH-SY5Y cells. Effects of oxidative stress and antioxidative factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for generation of oxidative stress in brain by MPTP: in vitro and in vivo studies in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidant defense of the brain: a role for astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The reduction of alpha-tocopherolquinone by human NAD(P)H: quinone oxidoreductase: the role of alpha-tocopherolhydroquinone as a cellular antioxidant

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An assay for superoxide dismutase activity in mammalian tissue homogenates

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species

1 reference

https://pubmed.ncbi.nlm.nih.gov/19408115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11064-009-9978-8

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

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