(Q45017201)

8 December 2017

title

Carotenoids and their metabolites are naturally occurring activators of gene expression via the pregnane X receptor (English)

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8 December 2017

author

Florian J. Schweigert

6

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8 December 2017

Paul Pfluger

4

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author name string

Ralph Rühl

1

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8 December 2017

Ronny Sczech

2

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8 December 2017

Nico Landes

3

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8 December 2017

Dirk Kluth

5

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8 December 2017

publication date

1 December 2004

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European Journal of Nutrition

8 December 2017

published in

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8 December 2017

volume

43

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8 December 2017

issue

6

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8 December 2017

page(s)

336-343

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https://scigraph.springernature.com/pub.10.1007/s00394-004-0475-1

8 December 2017

exact match

0 references

cites work

Phytol metabolites are circulating dietary factors that activate the nuclear receptor RXR

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00394-004-0475-1

An isocratic liquid chromatographic method with diode-array detection for the simultaneous determination of alpha-tocopherol, retinol, and five carotenoids in human serum

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00394-004-0475-1

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00394-004-0475-1

Identification, expression, and substrate specificity of a mammalian beta-carotene 15,15'-dioxygenase

21 January 2018

1 reference

12 December 2020

Quantitative analysis of constitutive and inducible CYPs mRNA expression in the HepG2 cell line using reverse transcription-competitive PCR.

1 reference

12 December 2020

Biosynthesis of all-trans-retinoic acid from all-trans-retinol: catalysis of all-trans-retinol oxidation by human P-450 cytochromes

1 reference

12 December 2020

Orphan nuclear receptors: shifting endocrinology into reverse

1 reference

12 December 2020

Nuclear hormone receptors and gene expression

1 reference

12 December 2020

The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers

1 reference

12 December 2020

Analysis of carotenoids in human and animal tissues

1 reference

12 December 2020

Humanized xenobiotic response in mice expressing nuclear receptor SXR.

1 reference

12 December 2020

Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

1 reference

12 December 2020

Chromatographic analysis of endogenous retinoids in tissues and serum

1 reference

12 December 2020

Vitamin E activates gene expression via the pregnane X receptor

1 reference

12 December 2020

The drug efflux pump MRP2: regulation of expression in physiopathological situations and by endogenous and exogenous compounds

1 reference

12 December 2020

Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma

1 reference

12 December 2020

Effects of provitamin A or non-provitamin A carotenoids on liver xenobiotic-metabolizing enzymes in mice

1 reference

12 December 2020

The role of hepatocyte RXR alpha in xenobiotic-sensing nuclear receptor-mediated pathways

1 reference

12 December 2020

Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites

1 reference

12 December 2020

Zonal down-regulation and redistribution of the multidrug resistance protein 2 during bile duct ligation in rat liver

1 reference

12 December 2020

The nuclear receptor superfamily: the second decade

1 reference

12 December 2020

P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.

1 reference

12 December 2020

Lycopene supplementation inhibits lung squamous metaplasia and induces apoptosis via up-regulating insulin-like growth factor-binding protein 3 in cigarette smoke-exposed ferrets.

1 reference

12 December 2020

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

1 reference

12 December 2020

Effects of retinoid treatment of rats on hepatic microsomal metabolism and cytochromes P450. Correlation between retinoic acid receptor/retinoid x receptor selectivity and effects on metabolic enzymes

1 reference

12 December 2020

Expression pattern and localization of beta,beta-carotene 15,15'-dioxygenase in different tissues

1 reference

12 December 2020

Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial

1 reference

12 December 2020

Effects of physiological versus pharmacological beta-carotene supplementation on cell proliferation and histopathological changes in the lungs of cigarette smoke-exposed ferrets.

1 reference

12 December 2020

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

1 reference

12 December 2020

Plasma carotenoids in normal men after a single ingestion of vegetables or purified beta-carotene

1 reference

12 December 2020

Antioxidant vitamins affect food animal immunity and health

1 reference

12 December 2020

Merck Frosst Award Lecture 1998. Molecular dissection of the human multidrug resistance P-glycoprotein

1 reference

12 December 2020

Metabolism of vitamin A and its active metabolite all-trans-retinoic acid in small intestinal enterocytes

1 reference

12 December 2020

Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor

1 reference

12 December 2020

Induction of cytochrome P450 enzymes and over-generation of oxygen radicals in beta-carotene supplemented rats.

1 reference

12 December 2020

Up-regulation of transporters of the MRP family by drugs and toxins

1 reference

12 December 2020

Exposing ferrets to cigarette smoke and a pharmacological dose of beta-carotene supplementation enhance in vitro retinoic acid catabolism in lungs via induction of cytochrome P450 enzymes

1 reference

12 December 2020

Measurement of cytochrome P450 gene induction in human hepatocytes using quantitative real-time reverse transcriptase-polymerase chain reaction.

1 reference

12 December 2020

The effect of beta-carotene on lung and skin carcinogenesis

1 reference

12 December 2020

Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: a study using adenovirus-mediated antisense targeting.

1 reference

12 December 2020

1 reference

12 December 2020

Use of the nuclear receptor PXR to predict drug interactions

1 reference

12 December 2020

cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats

1 reference

12 December 2020

Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

1 reference

12 December 2020

Identification and characterization of a mammalian enzyme catalyzing the asymmetric oxidative cleavage of provitamin A

1 reference

12 December 2020

Regulation of cyp3a gene transcription by the pregnane x receptor

1 reference

12 December 2020

Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation

1 reference

12 December 2020

Regulation of the rat glutathione S-transferase A2 gene by glucocorticoids: involvement of both the glucocorticoid and pregnane X receptors

1 reference

12 December 2020

Molecular analysis of vitamin A formation: cloning and characterization of beta-carotene 15,15'-dioxygenases

1 reference

12 December 2020

The enzymatic cleavage of beta-carotene: end of a controversy.

1 reference

12 December 2020

Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).

1 reference

12 December 2020

10.1007/S00394-004-0475-1

Identifiers

DOI

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Dimensions Publication ID

8 December 2017

1022849204

0 references

1 reference