(Q45068177)

9 December 2017

title

Acute hepatotoxicity of oncolytic adenoviruses in mouse models is associated with expression of wild-type E1a and induction of TNF-alpha (English)

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9 December 2017

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Heidrun Engler

1

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9 December 2017

Todd Machemer

2

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9 December 2017

Jennifer Philopena

3

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9 December 2017

Shu-Fen Wen

4

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9 December 2017

Erlinda Quijano

5

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9 December 2017

Murali Ramachandra

6

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9 December 2017

Van Tsai

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9 December 2017

Robert Ralston

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9 December 2017

language of work or name

English

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publication date

1 October 2004

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9 December 2017

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9 December 2017

volume

328

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9 December 2017

issue

1

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9 December 2017

page(s)

52-61

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CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors

9 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Blood clearance rates of adenovirus type 5 in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Systemic interleukin-6 responses following administration of adenovirus gene transfer vectors to humans by different routes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Adenovirus and cell cycle control

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Replication-selective viruses for cancer therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Induction by E1A oncogene expression of cellular susceptibility to lysis by TNF.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Modulation of the inflammatory properties and hepatotoxicity of recombinant adenovirus vectors by the viral E4 gene products.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Infection of Mouse Liver by Human Adenovirus Type 5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Mapping of cellular protein-binding sites on the products of early-region 1A of human adenovirus type 5.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

WEHI 164 subclone 13 assay for TNF: sensitivity, specificity, and reliability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Interleukin 1 receptor blockade attenuates the host inflammatory response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

A mouse model for investigating the molecular pathogenesis of adenovirus pneumonia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

The release of inflammatory cytokines from human peripheral blood mononuclear cells in vitro following exposure to adenovirus variants and capsid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Adenovirus immunoregulatory genes and their cellular targets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Retinoblastoma growth suppressor and a 300-kDa protein appear to regulate cellular DNA synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Evaluation of E1-mutant adenoviruses as conditionally replicating agents for cancer therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Purification of a type 5 recombinant adenovirus encoding human p53 by column chromatography

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Interferon alpha2b gene delivery using adenoviral vector causes inhibition of tumor growth in xenograft models from a variety of cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

An adenovirus type 5 early gene function regulates expression of other early viral genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Replication-selective virotherapy for cancer: Biological principles, risk management and future directions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Effect of adenovirus gene transfer vectors on the immunologic functions of mouse dendritic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

NK cells cause liver injury and facilitate the induction of T cell-mediated immunity to a viral liver infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Evaluation of the biodistribution, persistence, toxicity, and potential of germ-line transmission of a replication-competent human adenovirus following intraprostatic administration in the mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Specific depletion of human anti-adenovirus antibodies facilitates transduction in an in vivo model for systemic gene therapy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: a phase I trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

The adenoviral transcription factor, E1A 13S, trans-activates the human tumor necrosis factor-alpha promoter

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

The beige mutation in the mouse selectively impairs natural killer cell function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Adenovirus E1A oncogene expression in tumor cells enhances killing by TNF-related apoptosis-inducing ligand (TRAIL).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Adenoviral vectors stimulate murine natural killer cell responses and demonstrate antitumor activities in the absence of transgene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Tumor necrosis factor-alpha activation by adenovirus E1A 13S CR3 occurs in a cell-dependent and cell-independent manner

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Analytical anion-exchange HPLC of recombinant type-5 adenoviral particles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Tumor necrosis factor receptor and Fas signaling mechanisms.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

E3 gene manipulations affect oncolytic adenovirus activity in immunocompetent tumor models

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Development and validation of sensitive assays to quantitate gene expression after p53 gene therapy and paclitaxel chemotherapy using in vivo dosing in tumor xenograft models

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Development and characterization of recombinant adenoviruses encoding human p53 for gene therapy of cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Adenovirus genes that modulate the sensitivity of virus-infected cells to lysis by TNF.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Immune responses to adenoviruses: viral evasion mechanisms and their implications for the clinic.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Adenovirus E3 14.7K protein functions in the absence of other adenovirus proteins to protect transfected cells from tumor necrosis factor cytolysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

Adenovirus E3-10.4K/14.5K protein complex inhibits tumor necrosis factor-induced translocation of cytosolic phospholipase A2 to membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.043

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VIROL.2004.06.043

1 reference

9 December 2017

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