(Q45068235)

9 December 2017

title

ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks (English)

1 reference

9 December 2017

0 references

0 references

0 references

1 reference

Anindya Dutta

4

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Etsuko Shibata

series ordinal

3

object named as

Etsuko Shibata

1 reference

9 December 2017

Kyung Yong Lee

1

1 reference

9 December 2017

Jun-Sub Im

series ordinal

2

1 reference

9 December 2017

language of work or name

English

0 references

publication date

13 September 2017

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9 December 2017

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9 December 2017

volume

68

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9 December 2017

issue

1

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9 December 2017

page(s)

61-75.e5

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describes a project that uses

9 December 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5743198/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Asf1 facilitates dephosphorylation of Rad53 after DNA double-strand break repair

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MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex

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Double-strand break repair: 53BP1 comes into focus

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The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases

27 August 2018

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RIF1 counteracts BRCA1-mediated end resection during DNA repair

27 August 2018

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27 August 2018

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RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.

27 August 2018

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Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching

27 August 2018

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53BP1 regulates DSB repair using Rif1 to control 5' end resection

27 August 2018

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RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling

27 August 2018

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27 August 2018

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RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1.

27 August 2018

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27 August 2018

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The miR-99 family regulates the DNA damage response through its target SNF2H

27 August 2018

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Genomic analysis of marginal zone and lymphoplasmacytic lymphomas identified common and disease-specific abnormalities

27 August 2018

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ASF1A and ATM regulate H3K56-mediated cell-cycle checkpoint recovery in response to UV irradiation

27 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Critical role of monoubiquitination of histone H2AX protein in histone H2AX phosphorylation and DNA damage response

27 August 2018

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Monoubiquitination of H2AX protein regulates DNA damage response signaling

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Asf1b, the necessary Asf1 isoform for proliferation, is predictive of outcome in breast cancer

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Genomic profiling combined with gene expression profiling in primary central nervous system lymphoma.

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Identification of the MMS22L-TONSL complex that promotes homologous recombination

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Collaboration and competition between DNA double‐strand break repair pathways

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Regulation of homologous recombination in eukaryotes

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Identification of breast tumor mutations in BRCA1 that abolish its function in homologous DNA recombination

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

The DNA-damage response in human biology and disease

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

CBP/p300-mediated acetylation of histone H3 on lysine 56

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Pro-survival AKT and ERK signaling from EGFR and mutant EGFRvIII enhances DNA double-strand break repair in human glioma cells

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

DNA repair deficiency and neurological disease

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

An oligomerized 53BP1 tudor domain suffices for recognition of DNA double-strand breaks

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

53BP1 facilitates long-range DNA end-joining during V(D)J recombination

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Regulation of replication fork progression through histone supply and demand

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Histone chaperones: an escort network regulating histone traffic

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Integrative analysis of genomic aberrations associated with prostate cancer progression

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

DNA double-strand break repair: from mechanistic understanding to cancer treatment

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Differential usage of non-homologous end-joining and homologous recombination in double strand break repair

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

An ATR- and BRCA1-mediated Fanconi anemia pathway is required for activating the G2/M checkpoint and DNA damage repair upon rereplication

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

MDC1 interacts with Rad51 and facilitates homologous recombination

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Human Asf1 regulates the flow of S phase histones during replicational stress

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

MDC1 is a mediator of the mammalian DNA damage checkpoint

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

MDC1 is required for the intra-S-phase DNA damage checkpoint

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

53BP1, a mediator of the DNA damage checkpoint

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Interaction between the Drosophila CAF-1 and ASF1 chromatin assembly factors

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

A human homologue of yeast anti-silencing factor has histone chaperone activity

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

The RCAF complex mediates chromatin assembly during DNA replication and repair

27 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5743198

Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

27 August 2018

1 reference

31 March 2022

https://opencitations.net/index/coci/api/v1/citations/10.1126/SCISIGNAL.2004088

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

1 reference

31 March 2022

https://opencitations.net/index/coci/api/v1/citations/10.1158/2159-8290.CD-12-0095

Identifiers

DOI

10.1016/J.MOLCEL.2017.08.021

1 reference

9 December 2017

0 references

1 reference