(Q45068770)

9 December 2017

title

Immunisation with foamy virus Bet fusion proteins as novel strategy for HIV-1 epitope delivery (English)

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9 December 2017

3

Martin Löchelt

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9 December 2017

Michael Mühle

1

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9 December 2017

Kerstin Hoffmann

series ordinal

2

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9 December 2017

Joachim Denner

series ordinal

4

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9 December 2017

publication date

1 May 2013

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9 December 2017

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9 December 2017

volume

56

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9 December 2017

issue

1

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9 December 2017

page(s)

61-72

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AIDS/HIV. A boost for HIV vaccine design

9 December 2017

cites work

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The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infection

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HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages

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Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

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21 January 2018

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New paradigms for HIV/AIDS vaccine development

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Foamy virus biology and its application for vector development

21 January 2018

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Foamy virus vector integration sites in normal human cells

21 January 2018

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Treatment of canine leukocyte adhesion deficiency by foamy virus vectors expressing CD18 from a PGK promoter

21 January 2018

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Progress and prospects: foamy virus vectors enter a new age.

21 January 2018

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Foamy virus vectors expressing anti-HIV transgenes efficiently block HIV-1 replication.

21 January 2018

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Foamy virus vectors for gene transfer

21 January 2018

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Construction and characterization of efficient, stable and safe replication-deficient foamy virus vectors

21 January 2018

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Construction and functional characterization of feline foamy virus-based retroviral vectors

21 January 2018

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Application of chimeric feline foamy virus-based retroviral vectors for the induction of antiviral immunity in cats

21 January 2018

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Construction of infectious feline foamy virus genomes: cat antisera do not cross-neutralize feline foamy virus chimera with serotype-specific Env sequences

21 January 2018

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Characterization of the humoral immune response and virus replication in cats experimentally infected with feline foamy virus

21 January 2018

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Pattern of seroreactivity against feline foamy virus proteins in domestic cats from Germany.

21 January 2018

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Antibodies against Gag are diagnostic markers for feline foamy virus infections while Env and Bet reactivity is undetectable in a substantial fraction of infected cats

21 January 2018

1 reference

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Intra- and intercellular trafficking of the foamy virus auxiliary bet protein

21 January 2018

1 reference

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The membrane-proximal external region of the human immunodeficiency virus type 1 envelope: dominant site of antibody neutralization and target for vaccine design

21 January 2018

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Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.

21 January 2018

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A monomeric 3(10)-helix is formed in water by a 13-residue peptide representing the neutralizing determinant of HIV-1 on gp41

21 January 2018

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Crystal structure of the complex between the F(ab)' fragment of the cross-neutralizing anti-HIV-1 antibody 2F5 and the F(ab) fragment of its anti-idiotypic antibody 3H6

21 January 2018

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Crystal structure of HIV-1 gp41 including both fusion peptide and membrane proximal external regions

21 January 2018

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Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope

21 January 2018

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The membrane-proximal tryptophan-rich region of the HIV glycoprotein, gp41, forms a well-defined helix in dodecylphosphocholine micelles

21 January 2018

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HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

Role of HIV membrane in neutralization by two broadly neutralizing antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

Aromatic residues at the edge of the antibody combining site facilitate viral glycoprotein recognition through membrane interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site

21 January 2018

1 reference

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Antigenicity and immunogenicity of the HIV-1 gp41 epitope ELDKWA inserted into permissive sites of the MalE protein

21 January 2018

1 reference

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Construction of recombinant targeting immunogens incorporating an HIV-1 neutralizing epitope into sites of differing conformational constraint

21 January 2018

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Structure-function analysis of the epitope for 4E10, a broadly neutralizing human immunodeficiency virus type 1 antibody

21 January 2018

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Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.

21 January 2018

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Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41

21 January 2018

1 reference

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Functional links between the fusion peptide-proximal polar segment and membrane-proximal region of human immunodeficiency virus gp41 in distinct phases of membrane fusion

21 January 2018

1 reference

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Mode of interaction between the HIV-1-neutralizing monoclonal antibody 2F5 and its epitope

21 January 2018

1 reference

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Membrane-transferring sequences of the HIV-1 Gp41 ectodomain assemble into an immunogenic complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

The membrane proximal external region of the HIV-1 envelope glycoprotein gp41 contributes to the stabilization of the six-helix bundle formed with a matching N' peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

Structural constraints imposed by the conserved fusion peptide on the HIV-1 gp41 epitope recognized by the broadly neutralizing antibody 2F5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

Optimisation of expression and purification of the feline and primate foamy virus transmembrane envelope proteins using a 96 deep well screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

A statistically defined endpoint titer determination method for immunoassays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

Immunological properties of the transmembrane envelope protein of the feline foamy virus and its use for serological screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

De novo design and structural characterization of an alpha-helical hairpin peptide: a model system for the study of protein folding intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

Solution structure of alpha t alpha, a helical hairpin peptide of de novo design

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

The HIV Env-mediated fusion reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

Heterologous epitope-scaffold prime:boosting immuno-focuses B cell responses to the HIV-1 gp41 2F5 neutralization determinant

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

Elicitation of structure-specific antibodies by epitope scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

Progress towards the development of a HIV-1 gp41-directed vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

HIV-1 gp41 core with exposed membrane-proximal external region inducing broad HIV-1 neutralizing antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

Structural Analysis and Assembly of the HIV-1 Gp41 Amino-Terminal Fusion Peptide and the Pretransmembrane Amphipathic-At-Interface Sequence†

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8387-X

Conformational constraints imposed on a pan-neutralizing HIV-1 antibody epitope result in increased antigenicity but not neutralizing response

21 January 2018

1 reference

12 December 2020

An evolutionarily conserved splice generates a secreted env-Bet fusion protein during human foamy virus infection

1 reference

12 December 2020

The replication strategy of foamy viruses.

1 reference

12 December 2020

Foamy viruses are unconventional retroviruses

1 reference

12 December 2020

Refocusing neutralizing antibody response by targeted dampening of an immunodominant epitope.

1 reference

12 December 2020

A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1

1 reference

12 December 2020

HIV-1 vaccine development: constrained peptide immunogens show improved binding to the anti-HIV-1 gp41 MAb

1 reference

12 December 2020

A conserved tryptophan-rich motif in the membrane-proximal region of the human immunodeficiency virus type 1 gp41 ectodomain is important for Env-mediated fusion and virus infectivity.

1 reference

12 December 2020

10.1007/S12026-013-8387-X

Identifiers

DOI

1 reference

Dimensions Publication ID

9 December 2017

1004458570

0 references

1 reference