(Q45081457)

9 December 2017

title

Molecular and biochemical characterization of the Skp2-Cks1 binding interface (English)

1 reference

9 December 2017

Wei Wang

1

1 reference

9 December 2017

Dana Ungermannova

series ordinal

2

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9 December 2017

Lin Chen

series ordinal

3

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9 December 2017

Xuedong Liu

series ordinal

4

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9 December 2017

language of work or name

English

0 references

publication date

27 September 2004

1 reference

Journal of Biological Chemistry

9 December 2017

published in

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9 December 2017

volume

279

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9 December 2017

issue

49

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9 December 2017

page(s)

51362-51369

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CDK inhibitors: positive and negative regulators of G1-phase progression

9 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27Kip1.

21 January 2018

1 reference

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Deregulated degradation of the cdk inhibitor p27 and malignant transformation.

21 January 2018

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Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

Skp2 is oncogenic and overexpressed in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

Role of the F-box protein Skp2 in lymphomagenesis

21 January 2018

1 reference

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Cyclin E-CDK2 is a regulator of p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.

21 January 2018

1 reference

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Protein-protein interactions involved in the recognition of p27 by E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

Three different binding sites of Cks1 are required for p27-ubiquitin ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

Protein destruction: adapting roles for Cks proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

F-box protein Grr1 interacts with phosphorylated targets via the cationic surface of its leucine-rich repeat

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

A negatively charged amino acid in Skp2 is required for Skp2-Cks1 interaction and ubiquitination of p27Kip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

Skp2 regulates Myc protein stability and activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

A splice variant of Skp2 is retained in the cytoplasm and fails to direct cyclin D1 ubiquitination in the uterine cancer cell line SK-UT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

Negative regulation of SCFSkp2 ubiquitin ligase by TGF-beta signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405944200

Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer

21 January 2018

2 references

30 December 2023

https://opencitations.net/index/api/v1/citations/10.1172/JCI0215795

30 December 2023

https://opencitations.net/index/api/v1/citations/10.1172/JCI15795

Identifiers

DOI

10.1074/JBC.M405944200

1 reference

9 December 2017

1 reference