(Q45179812)

English

Potential beneficial metabolic interactions between tamoxifen and isoflavones via cytochrome P450-mediated pathways in female rat liver microsomes

scientific article published in November 2004

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Potential beneficial metabolic interactions between tamoxifen and isoflavones via cytochrome P450-mediated pathways in female rat liver microsomes (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

1 reference

based on heuristic

inferred from title

author name string

Jun Chen

1

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Steven C Halls

2

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Joshua F Alfaro

3

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Zhaohui Zhou

4

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Ming Hu

5

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

publication date

1 November 2004

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Pharmaceutical Research

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

21

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

2095-2104

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Clinical characteristics and pharmacokinetics of purified soy isoflavones: single-dose administration to healthy men

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biotransformation of lovastatin. IV. Identification of cytochrome P450 3A proteins as the major enzymes responsible for the oxidative metabolism of lovastatin in rat and human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative metabolism of the soy isoflavones daidzein and genistein in humans in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-hydroxytamoxifen, a genotoxic metabolite of tamoxifen in the rat: identification and quantification in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thalidomide metabolism by the CYP2C subfamily.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of CYP1A2 as the main isoform for the phase I hydroxylated metabolism of genistein and a prodrug converting enzyme of methylated isoflavones

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Phase II study of high-dose tamoxifen in patients with hormone-refractory prostate cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of flavonoids via enteric recycling: role of intestinal disposition

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of genistein by rat and human cytochrome P450s

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phytoestrogens: the "natural" selective estrogen receptor modulators?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The therapeutic potential of phytoestrogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative in vitro metabolism of the soy phytoestrogens daidzein and genistein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of biologically active metabolites of tamoxifen on the proliferation kinetics of MCF-7 human breast cancer cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen and toremifene treatment of breast cancer and risk of subsequent endometrial cancer: a population-based case-control study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soy for breast cancer survivors: a critical review of the literature

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of tamoxifen by recombinant human cytochrome P450 enzymes: formation of the 4-hydroxy, 4'-hydroxy and N-desmethyl metabolites and isomerization of trans-4-hydroxytamoxifen.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and quantification of tamoxifen-DNA adducts in the liver of rats and mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparative study of tamoxifen metabolism in female rat, mouse and human liver microsomes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of carcinogenesis by dietary polyphenolic compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidation of ranitidine by isozymes of flavin-containing monooxygenase and cytochrome P450.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioavailability of pure isoflavones in healthy humans and analysis of commercial soy isoflavone supplements

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary phytoestrogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen metabolites in patients on long-term adjuvant therapy for breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-oestrogenic drugs and endometrial cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variable contribution of cytochromes P450 2D6, 2C9 and 3A4 to the 4-hydroxylation of tamoxifen by human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. II. Flavin-containing monooxygenase-mediated N-oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Understanding the genotoxicity of tamoxifen?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of phase I and phase II metabolites of tamoxifen in breast cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of tamoxifen-DNA adducts in the endometrium of women treated with tamoxifen.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selectivities of human cytochrome P450 inhibitors toward rat P450 isoforms: study with cDNA-expressed systems of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic inhibitory effects of genistein and tamoxifen on human dysplastic and malignant epithelial breast cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absorption and metabolism of flavonoids in the caco-2 cell culture model and a perused rat intestinal model

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of tamoxifen metabolites in human Hep G2 cell line, human liver homogenate, and patients on long-term therapy for breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary agents in cancer prevention: flavonoids and isoflavonoids.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of cytochromes P450 in liver and kidney of rats treated with di-(2-ethylhexyl)phthalate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sulfation of alpha-hydroxytamoxifen catalyzed by human hydroxysteroid sulfotransferase results in tamoxifen-DNA adducts

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen and genistein synergistically down-regulate signal transduction and proliferation in estrogen receptor-negative human breast carcinoma MDA-MB-435 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple mechanisms in indomethacin-induced impairment of hepatic cytochrome P450 enzymes in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of alternative therapies for menopause symptoms: results of a population-based survey

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective estrogen receptor modulation and reduction in risk of breast cancer, osteoporosis, and coronary heart disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemiluminescence associated with the oxidative metabolism of salicylic acid in rat liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phytoestrogens as hormone replacement therapy: an evidence-based approach

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimised analysis of tamoxifen and its main metabolites in the plasma and cytosol of mammary tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen therapy for ovarian cancer in the adjuvant and advanced settings: systematic review of the literature and implications for future research.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of dextromethorphan in vitro: involvement of cytochromes P450 2D6 and 3A3/4, with a possible role of 2E1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15587933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/B:PHAM.0000048202.92930.61

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

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