(Q45242538)

11 December 2017

Damage to the endoplasmic reticulum and activation of apoptotic machinery by oxidative stress in ischemic neurons (English)

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11 December 2017

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endoplasmic reticulum

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author name string

Takeshi Hayashi

1

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11 December 2017

Atsushi Saito

2

1 reference

11 December 2017

Shuzo Okuno

3

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11 December 2017

Michel Ferrand-Drake

4

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11 December 2017

Robert L Dodd

5

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11 December 2017

Pak H Chan

6

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11 December 2017

1 January 2005

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Journal of Cerebral Blood Flow & Metabolism

11 December 2017

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11 December 2017

25

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11 December 2017

1

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11 December 2017

41-53

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Changes in the phosphorylation of initiation factor eIF-2alpha, elongation factor eEF-2 and p70 S6 kinase after transient focal cerebral ischaemia in mice.

11 December 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Pathological implications of nitric oxide, superoxide and peroxynitrite formation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

The endoplasmic reticulum: a multifunctional signaling organelle

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https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine

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https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Role of oxidants in ischemic brain damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Reactive oxygen radicals in signaling and damage in the ischemic brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Brain infarction is not reduced in SOD-1 transgenic mice after a permanent focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Overexpression of SOD1 in transgenic rats protects vulnerable neurons against ischemic damage after global cerebral ischemia and reperfusion.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

CCAAT/enhancer-binding protein beta plays a regulatory role in differentiation and apoptosis of neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Molecular pathways of protein synthesis inhibition during brain reperfusion: implications for neuronal survival or death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Effects of hypoxanthine-xanthine oxidase on Ca2+ stores and protein synthesis in human endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Physical and functional association between GADD153 and CCAAT/enhancer-binding protein beta during cellular stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Organelle-specific initiation of cell death pathways

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https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Co-involvement of mitochondria and endoplasmic reticulum in regulation of apoptosis: changes in cytochrome c, Bcl-2 and Bax in the hippocampus of aluminum-treated rabbits

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Transcriptional and translational control in the Mammalian unfolded protein response

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https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Regulated translation initiation controls stress-induced gene expression in mammalian cells

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https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Induction of GRP78 by ischemic preconditioning reduces endoplasmic reticulum stress and prevents delayed neuronal cell death

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https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Oxidative Damage to the Endoplasmic Reticulum is Implicated in Ischemic Neuronal Cell Death

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https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Oxidative injury to the endoplasmic reticulum in mouse brains after transient focal ischemia

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https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Protein aggregation after transient cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Amino acid limitation regulates CHOP expression through a specific pathway independent of the unfolded protein response.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Delayed neuronal death in the gerbil hippocampus following ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Expression of the endoplasmic reticulum molecular chaperone (ORP150) rescues hippocampal neurons from glutamate toxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Brain ischemia and reperfusion activates the eukaryotic initiation factor 2alpha kinase, PERK.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Free radical pathways in CNS injury

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

The unfolding tale of the unfolded protein response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

The metabotropic GABAB receptor directly interacts with the activating transcription factor 4

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Evidence of phosphorylation of Akt and neuronal survival after transient focal cerebral ischemia in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Changes in brain energy metabolism and protein synthesis following transient bilateral ischemia in the gerbil.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Influence of oxidative stress on induced tolerance to ischemia in gerbil hippocampal neurons.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

4-Hydroxynonenal as a biological signal: molecular basis and pathophysiological implications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Disturbances of calcium homeostasis within the endoplasmic reticulum may contribute to the development of ischemic-cell damage.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Disturbances of the functioning of endoplasmic reticulum: a key mechanism underlying neuronal cell injury?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Activation of gadd153 expression through transient cerebral ischemia: evidence that ischemia causes endoplasmic reticulum dysfunction.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Overexpression of copper/zinc superoxide dismutase in transgenic mice protects against neuronal cell death after transient focal ischemia by blocking activation of the Bad cell death signaling pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Models for studying long-term recovery following forebrain ischemia in the rat. 2. A 2-vessel occlusion model.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

DNA fragmentation and HSP70 protein induction in hippocampus and cortex occurs in separate neurons following permanent middle cerebral artery occlusions.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

The oxidative inactivation of sarcoplasmic reticulum Ca(2+)-ATPase by peroxynitrite

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Identification of novel stress-induced genes downstream of chop

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600005

7 January 2021

Identifiers

DOI

10.1038/SJ.JCBFM.9600005

1 reference

11 December 2017

1 reference