(Q45250001)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

Insulin receptor substrate 2 is essential for maturation and survival of photoreceptor cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

main subject

photoreceptor protein

0 references

1 reference

13

Morris F White

1 reference

11 December 2017

Xianjin Yi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Markus Schubert

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Neal S Peachey

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Kiyoshi Suzuma

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Deborah J Burks

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Jake A Kushner

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Izumi Suzuma

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Christopher Cahill

8

1 reference

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8 January 2020

Carrie L Flint

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Matthew A Dow

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Rebecca L Leshan

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

George L King

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Morris F White

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

language of work or name

English

0 references

publication date

1 February 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

volume

25

1 reference

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8 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

page(s)

1240-1248

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

Activation of caspase-3 in the retina of transgenic rats with the rhodopsin mutation s334ter during photoreceptor degeneration

8 January 2020

cites work

1 reference

12 December 2020

Neurotrophins and other growth factors in the generation of retinal neurons

1 reference

12 December 2020

Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

1 reference

12 December 2020

Retinal degeneration in tulp1-/- mice: vesicular accumulation in the interphotoreceptor matrix

1 reference

12 December 2020

Insulin-like growth factor-I protects axotomized rat retinal ganglion cells from secondary death via PI3-K-dependent Akt phosphorylation and inhibition of caspase-3 In vivo

1 reference

12 December 2020

Expression of Bcl-2 protects against photoreceptor degeneration in retinal degeneration slow (rds) mice

1 reference

12 December 2020

In vivo regulation of cell death by embryonic (pro)insulin and the insulin receptor during early retinal neurogenesis.

1 reference

12 December 2020

Soluble factors and the development of rod photoreceptors

1 reference

12 December 2020

Restoration of photoreceptor ultrastructure and function in retinal degeneration slow mice by gene therapy.

1 reference

12 December 2020

Insulin receptor and insulin receptor substrate-I in rat retinae

1 reference

12 December 2020

Role of brain insulin receptor in control of body weight and reproduction

1 reference

12 December 2020

IRS-2 pathways integrate female reproduction and energy homeostasis

1 reference

12 December 2020

Retinal degeneration in the nervous mutant mouse. IV. Inner retinal changes

1 reference

12 December 2020

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

1 reference

12 December 2020

Insulin rescues retinal neurons from apoptosis by a phosphatidylinositol 3-kinase/Akt-mediated mechanism that reduces the activation of caspase-3.

1 reference

12 December 2020

PKB/Akt: a key mediator of cell proliferation, survival and insulin responses?

1 reference

12 December 2020

Signalling pathways in Drosophila and vertebrate retinal development

1 reference

12 December 2020

Interaction of the insulin receptor beta-subunit with phosphatidylinositol 3-kinase in bovine ROS.

1 reference

12 December 2020

The tubby-like proteins, a family with roles in neuronal development and function.

1 reference

12 December 2020

Caspase-3 inhibitor transiently delays inherited retinal degeneration in C3H mice carrying the rd gene

1 reference

12 December 2020

Pdx1 restores beta cell function in Irs2 knockout mice

1 reference

12 December 2020

A Role for phosphoinositide 3-kinase in the control of cell division and survival during retinal development

1 reference

12 December 2020

A review of the literature of Bardet-Biedl disease and report of three cases associated with metabolic syndrome and diagnosed after the age of fifty

1 reference

12 December 2020

Effects of adeno-associated virus-vectored ciliary neurotrophic factor on retinal structure and function in mice with a P216L rds/peripherin mutation

1 reference

12 December 2020

The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels

1 reference

12 December 2020

Control of cell survival by IGF signaling pathways.

1 reference

12 December 2020

Three new cases of Alström syndrome

1 reference

12 December 2020

Axons guided by insulin receptor in Drosophila visual system

1 reference

12 December 2020

Characterization of insulin signaling in rat retina in vivo and ex vivo

1 reference

12 December 2020

1 reference

12 December 2020

cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.

1 reference

12 December 2020

Expression and localization of bestrophin during normal mouse development

1 reference

12 December 2020

Neural remodeling in retinal degeneration.

1 reference

12 December 2020

Apoptotic death of photoreceptors in the streptozotocin-induced diabetic rat retina

1 reference

12 December 2020

Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation

1 reference

12 December 2020

Electrophysiological analysis of visual function in mutant mice.

1 reference

12 December 2020

Differentiation of marrow stromal cells into photoreceptors in the rat eye.

1 reference

12 December 2020

Energy metabolism of rabbit retina as related to function: high cost of Na+ transport

1 reference

12 December 2020

Major role of BAX in apoptosis during retinal development and in establishment of a functional postnatal retina

1 reference

12 December 2020

Progress toward understanding the genetic and biochemical mechanisms of inherited photoreceptor degenerations

1 reference

12 December 2020

Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes

1 reference

12 December 2020

Insulin signaling in health and disease

1 reference

12 December 2020

Role for neuronal insulin resistance in neurodegenerative diseases

1 reference

12 December 2020

Roles of the bHLH gene Hes1 in retinal morphogenesis

1 reference

12 December 2020

Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system

1 reference

12 December 2020

A mild form of Alstrom disease associated with metabolic syndrome and very high fasting serum free fatty acids: two cases diagnosed in adult age.

1 reference

12 December 2020

Leber congenital amaurosis linked to AIPL1: a mouse model reveals destabilization of cGMP phosphodiesterase

1 reference

12 December 2020

Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes

1 reference

12 December 2020

A computational model of the amplitude and implicit time of the b-wave of the human ERG

1 reference

12 December 2020

The Inheritance of a Retinal Abnormality in White Mice

1 reference

12 December 2020

Mutation spectrum of the rhodopsin gene among patients with autosomal dominant retinitis pigmentosa

1 reference

12 December 2020

Localization of insulin-like growth factor-1 binding sites in the embryonic chicken eye.

1 reference

12 December 2020

Retinal insulin receptors: localization using a polyclonal anti-insulin receptor antibody.

1 reference

12 December 2020

Synaptogenesis in the photoreceptor terminal of the mouse retina

1 reference

12 December 2020

Mouse model for Usher syndrome: linkage mapping suggests homology to Usher type I reported at human chromosome 11p15.

1 reference

12 December 2020

Autocrine/paracrine role of insulin-related growth factors in neurogenesis: local expression and effects on cell proliferation and differentiation in retina

1 reference

12 December 2020

Strategies for rescue of retinal photoreceptor cells

1 reference

12 December 2020

Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa

1 reference

12 December 2020

Apoptosis: final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice

1 reference

12 December 2020

bcl-2 overexpression reduces apoptotic photoreceptor cell death in three different retinal degenerations

1 reference

12 December 2020

Insulin-like growth factor-I stimulates neurogenesis in chick retina by regulating expression of the alpha 6 integrin subunit.

1 reference

12 December 2020

Gene-based approach to human gene-phenotype correlations

1 reference

12 December 2020

Recessive mutations in the gene encoding the tubby-like protein TULP1 in patients with retinitis pigmentosa

1 reference

12 December 2020

TULP1 mutation in two extended Dominican kindreds with autosomal recessive retinitis pigmentosa.

1 reference

12 December 2020

Blocking apoptosis prevents blindness in Drosophila retinal degeneration mutants.

1 reference

12 December 2020

Assessing abnormal rod photoreceptor activity with the a-wave of the electroretinogram: applications and methods

1 reference

12 December 2020

Disruption of IRS-2 causes type 2 diabetes in mice

1 reference

12 December 2020

Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin

1 reference

12 December 2020

The role of PI 3-kinase in insulin action

1 reference

12 December 2020

(Pro)insulin and insulin-like growth factor I complementary expression and roles in early development.

1 reference

12 December 2020

10.1523/JNEUROSCI.3664-04.2005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15689562%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference