(Q45293567)

11 December 2017

title

Motor deficits associated with Huntington's disease occur in the absence of striatal degeneration in BACHD transgenic mice (English)

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11 December 2017

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11 December 2017

Daniel C Christie

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Trent M. Woodruff

object named as

Trent M Woodruff

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Richard Gordon

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Richard Gordon

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author name string

Rui Li

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11 December 2017

Vinod Kumar

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11 December 2017

publication date

21 February 2016

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11 December 2017

published in

Human Molecular Genetics

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11 December 2017

volume

25

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11 December 2017

issue

9

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11 December 2017

page(s)

1780-1791

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Neuroinflammation in Huntington's disease

11 December 2017

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Increased Body Weight of the BAC HD Transgenic Mouse Model of Huntington's Disease Accounts for Some but Not All of the Observed HD-like Motor Deficits.

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Marked differences in neurochemistry and aggregates despite similar behavioural and neuropathological features of Huntington disease in the full-length BACHD and YAC128 mice

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Caspase-6 activity in a BACHD mouse modulates steady-state levels of mutant huntingtin protein but is not necessary for production of a 586 amino acid proteolytic fragment.

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21 January 2018

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Expression of mutant huntingtin in leptin receptor-expressing neurons does not control the metabolic and psychiatric phenotype of the BACHD mouse

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Hypothalamic expression of mutant huntingtin contributes to the development of depressive-like behavior in the BAC transgenic mouse model of Huntington's disease

21 January 2018

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Dysfunctions in circadian behavior and physiology in mouse models of Huntington's disease

21 January 2018

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Full-length huntingtin levels modulate body weight by influencing insulin-like growth factor 1 expression

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/HMG/DDW050

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11 December 2017

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