(Q45303991)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869595%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

title

A toxic mutant huntingtin species is resistant to selective autophagy (English)

1 reference

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29 March 2020

1 reference

7

1 reference

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29 March 2020

author name string

Yuhua Fu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869595%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Peng Wu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869595%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Yuyin Pan

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869595%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Xiaoli Sun

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869595%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Huiya Yang

5

1 reference

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29 March 2020

Marian Difiglia

6

1 reference

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29 March 2020

publication date

4 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869595%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

published in

Nature Chemical Biology

1 reference

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29 March 2020

volume

13

1 reference

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29 March 2020

issue

11

1 reference

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29 March 2020

page(s)

1152-1154

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869595%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nchembio.2461

29 March 2020

exact match

0 references

cites work

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Disease-Associated Polyglutamine Stretches in Monomeric Huntingtin Adopt a Compact Structure

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Anti-PolyQ Antibodies Recognize a Short PolyQ Stretch in Both Normal and Mutant Huntingtin Exon 1.

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Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

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Selective autophagy mediated by autophagic adapter proteins

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The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

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21 January 2018

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LC3B is indispensable for selective autophagy of p62 but not basal autophagy

21 January 2018

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TR-FRET assays of Huntingtin protein fragments reveal temperature and polyQ length-dependent conformational changes

21 January 2018

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A role for ubiquitin in selective autophagy

21 January 2018

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

21 January 2018

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Monoclonal antibodies recognize distinct conformational epitopes formed by polyglutamine in a mutant huntingtin fragment

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Single-step detection of mutant huntingtin in animal and human tissues: a bioassay for Huntington's disease

21 January 2018

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Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats

21 January 2018

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21 January 2018

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21 January 2018

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