(Q45729099)

15 December 2017

Non-degradative ubiquitination of the Notch1 receptor by the E3 ligase MDM2 activates the Notch signalling pathway (English)

1 reference

15 December 2017

protein ubiquitination

1 reference

Susanne Pettersson

1

1 reference

15 December 2017

Matylda Sczaniecka

2

1 reference

15 December 2017

Lorna McLaren

3

1 reference

15 December 2017

Fiona Russell

4

1 reference

15 December 2017

Karen Gladstone

5

1 reference

15 December 2017

Ted Hupp

6

1 reference

15 December 2017

Maura Wallace

7

1 reference

15 December 2017

language of work or name

English

0 references

publication date

1 March 2013

1 reference

15 December 2017

1 reference

15 December 2017

450

1 reference

15 December 2017

3

1 reference

15 December 2017

523-536

1 reference

An overview of the Notch signalling pathway

15 December 2017

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Notch signalling: a simple pathway becomes complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Notch targets and their regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Notch signalling pathway and human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Notch signaling pathway and cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Roles of ubiquitin signaling in transcription regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

The multiple functions of Numb

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Aberrant activation of notch signaling in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

The Mdm2 oncoprotein interacts with the cell fate regulator Numb

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Mammalian Numb is a target protein of Mdm2, ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

MDM2 protein-mediated ubiquitination of numb protein: identification of a second physiological substrate of MDM2 that employs a dual-site docking mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Regulation of the IRF-1 tumour modifier during the response to genotoxic stress involves an ATM-dependent signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

MDM2 chaperones the p53 tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Critical contribution of the MDM2 acidic domain to p53 ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

A function for the RING finger domain in the allosteric control of MDM2 conformation and activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H)

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Notch in T-ALL: new players in a complex disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Critical role for a central part of Mdm2 in the ubiquitylation of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Polyubiquitin chains: polymeric protein signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

BRCA1-mediated ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Trp53 regulates Notch 4 signaling through Mdm2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Notch signaling in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

Therapeutic potential of gamma-secretase inhibitors and modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

NOTCH inhibition and glucocorticoid therapy in T-cell acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121249

21 January 2018

Identifiers

DOI

10.1042/BJ20121249

1 reference

release_vaa7cdayvjbpvinezcnvrghhyy

15 December 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/vaa7cdayvjbpvinezcnvrghhyy

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference