(Q45856234)

17 December 2017

review article

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title

New p53-based anti-cancer therapeutic strategies (English)

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17 December 2017

author name string

K G Wiman

series ordinal

1

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17 December 2017

publication date

1 December 1998

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17 December 2017

published in

Medical Oncology

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17 December 2017

volume

15

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17 December 2017

issue

4

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17 December 2017

page(s)

222-228

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17 December 2017

https://scigraph.springernature.com/pub.10.1007/bf02787204

exact match

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cites work

Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF02787204

Regulation of the specific DNA binding function of p53

21 January 2018

1 reference

12 December 2020

Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

1 reference

12 December 2020

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor

1 reference

12 December 2020

Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases

1 reference

12 December 2020

Induction of the growth inhibitor IGF-binding protein 3 by p53

1 reference

12 December 2020

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

12 December 2020

Small peptides activate the latent sequence-specific DNA binding function of p53.

1 reference

12 December 2020

Microinjection of monoclonal antibody PAb421 into human SW480 colorectal carcinoma cells restores the transcription activation function to mutant p53.

1 reference

12 December 2020

p53-mediated apoptosis in HeLa cells can be overcome by excess pRB

1 reference

12 December 2020

p53: a cell cycle regulator activated by DNA damage

1 reference

12 December 2020

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

12 December 2020

Allosteric activation of latent p53 tetramers

1 reference

12 December 2020

The dihedral symmetry of the p53 tetramerization domain mandates a conformational switch upon DNA binding

1 reference

12 December 2020

Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen

1 reference

12 December 2020

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

1 reference

12 December 2020

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

12 December 2020

WAF1, a potential mediator of p53 tumor suppression

1 reference

12 December 2020

Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants.

1 reference

12 December 2020

The p53-mdm-2 autoregulatory feedback loop

1 reference

12 December 2020

Activation of the cryptic DNA binding function of mutant forms of p53.

1 reference

12 December 2020

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

1 reference

12 December 2020

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

1 reference

12 December 2020

Interactions of human papillomavirus transforming proteins with the products of tumor suppressor genes.

1 reference

12 December 2020

Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA.

1 reference

12 December 2020

p53: puzzle and paradigm

1 reference

12 December 2020

Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer

1 reference

12 December 2020

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

1 reference

12 December 2020

The single-stranded DNA end binding site of p53 coincides with the C-terminal regulatory region.

1 reference

12 December 2020

Structure-based rescue of common tumor-derived p53 mutants

1 reference

12 December 2020

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

1 reference

12 December 2020

1 reference

12 December 2020

Restoration of the transcription activation function to mutant p53 in human cancer cells

1 reference

12 December 2020

Identification of a novel p53 functional domain that is necessary for efficient growth suppression

1 reference

12 December 2020

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

1 reference

12 December 2020

Adenovirally transferred p16INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death

1 reference

12 December 2020

Mdm2 promotes the rapid degradation of p53

1 reference

12 December 2020

Regulation of p53 stability by Mdm2

1 reference

12 December 2020

Progress of the smart bomb cancer virus

1 reference

12 December 2020

Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain

1 reference

12 December 2020

ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

1 reference

12 December 2020

Synergistic activation of transcription by CBP and p53

1 reference

12 December 2020

Binding and modulation of p53 by p300/CBP coactivators

1 reference

12 December 2020

The polyproline region of p53 is required to activate apoptosis but not growth arrest.

1 reference

12 December 2020

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

1 reference

12 December 2020

A model for p53-induced apoptosis

1 reference

12 December 2020

From bench top to bedside

1 reference

12 December 2020

ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins

1 reference

12 December 2020

14-3-3sigma is a p53-regulated inhibitor of G2/M progression

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02787204

1 reference

17 December 2017

Dimensions Publication ID

0 references

1 reference

17 December 2017