(Q45861150)

17 December 2017

title

Stem cell-derived erythroid cells mediate long-term systemic protein delivery (English)

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17 December 2017

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Alex H Chang

1

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17 December 2017

Matthias T Stephan

series ordinal

2

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17 December 2017

Michel Sadelain

series ordinal

3

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17 December 2017

publication date

16 July 2006

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17 December 2017

published in

Nature Biotechnology

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17 December 2017

volume

24

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17 December 2017

issue

8

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17 December 2017

page(s)

1017-1021

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/nbt1227

exact match

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cites work

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Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo

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21 January 2018

Locus control regions

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Sustained transgene expression by human cord blood derived CD34+ cells transduced with simian immunodeficiency virus agmTYO1-based vectors carrying the human coagulation factor VIII gene in NOD/SCID mice

21 January 2018

1 reference

Recombinant factor VIII expression in hematopoietic cells following lentiviral transduction.

21 January 2018

1 reference

Permanent partial phenotypic correction and tolerance in a mouse model of hemophilia B by stem cell gene delivery of human factor IX.

21 January 2018

1 reference

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

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Occurrence of leukaemia following gene therapy of X-linked SCID.

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Insertional oncogenesis in gene therapy: how much of a risk?

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Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation.

21 January 2018

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Novel therapeutic approach for hemophilia using gene delivery of an engineered secreted activated Factor VII.

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21 January 2018

Identifiers

DOI

10.1038/NBT1227

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17 December 2017

Dimensions Publication ID

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17 December 2017