(Q45869421)

English

Improved human beta-globin expression from self-inactivating lentiviral vectors carrying the chicken hypersensitive site-4 (cHS4) insulator element

scientific article published on 10 July 2007

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/17622240

Improved human beta-globin expression from self-inactivating lentiviral vectors carrying the chicken hypersensitive site-4 (cHS4) insulator element (English)

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/17622240

author name string

Paritha I Arumugam

1

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/17622240

Jessica Scholes

2

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/17622240

Natalya Perelman

3

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/17622240

Ping Xia

4

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/17622240

Jiing-Kuan Yee

5

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/17622240

Punam Malik

6

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/17622240

publication date

10 July 2007

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/17622240

Molecular Therapy

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/17622240

15

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/17622240

1863-1871

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/17622240

10

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/17622240

Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of the human beta-globin gene after retroviral transfer into murine erythroleukemia cells and human BFU-E cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Retroviral vectors aimed at the gene therapy of human beta-globin gene disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

High-level beta-globin expression after retroviral transfer of locus activation region-containing human beta-globin gene derivatives into murine erythroleukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutagenesis of retroviral vectors transducing human beta-globin gene and beta-globin locus control region derivatives results in stable transmission of an active transcriptional structure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Retroviral transfer of a human beta-globin/delta-globin hybrid gene linked to beta locus control region hypersensitive site 2 aimed at the gene therapy of sickle cell disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Therapeutic haemoglobin synthesis in beta-thalassaemic mice expressing lentivirus-encoded human beta-globin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Permanent and panerythroid correction of murine beta thalassemia by multiple lentiviral integration in hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

The degree of phenotypic correction of murine beta -thalassemia intermedia following lentiviral-mediated transfer of a human gamma-globin gene is influenced by chromosomal position effects and vector copy number

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Extended beta-globin locus control region elements promote consistent therapeutic expression of a gamma-globin lentiviral vector in murine beta-thalassemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

HIV-1 integration in the human genome favors active genes and local hotspots

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcription start regions in the human genome are favored targets for MLV integration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

High-level beta-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel murine model of Cooley anemia and its rescue by lentiviral-mediated human beta-globin gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Gene expression in proliferating human erythroid cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Development of virus vectors for gene therapy of beta chain hemoglobinopathies: flanking with a chromatin insulator reduces gamma-globin gene silencing in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Topological constraints governing the use of the chicken HS4 chromatin insulator in oncoretrovirus vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Performance- and safety-enhanced lentiviral vectors containing the human interferon-beta scaffold attachment region and the chicken beta-globin insulator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

The protein CTCF is required for the enhancer blocking activity of vertebrate insulators

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of the chicken beta-globin insulator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Genomic organization of gypsy chromatin insulators in Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of the beta globin locus by transcription factors and chromatin modifiers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

The insulation of genes from external enhancers and silencing chromatin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

The 5'-HS4 chicken beta-globin insulator is a CTCF-dependent nuclear matrix-associated element

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Successful correction of the human beta-thalassemia major phenotype using a lentiviral vector

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Hematopoietic stem cell gene therapy of murine protoporphyria by methylguanine-DNA-methyltransferase-mediated in vivo drug selection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional requirements for phenotypic correction of murine beta-thalassemia: implications for human gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

The cHS4 insulator increases the probability of retroviral expression at random chromosomal integration sites.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Position-effect protection and enhancer blocking by the chicken beta-globin insulator are separable activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Insertion mutagenesis of embryonal carcinoma cells by retroviruses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct classes of factor-independent mutants can be isolated after retroviral mutagenesis of a human myeloid stem cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Murine leukemia induced by retroviral gene marking

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Side effects of retroviral gene transfer into hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

High-level erythroid-specific gene expression in primary human and murine hematopoietic cells with self-inactivating lentiviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

A mouse model for beta 0-thalassemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300259

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.MT.6300259

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/17622240

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/17622240

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q45869421&oldid=2087703020"