(Q45902248)

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The specific, reversible JNK inhibitor SP600125 improves survivability and attenuates neuronal cell death in experimental cerebral malaria (ECM).

scientific article published on 28 February 2013

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/23455938

The specific, reversible JNK inhibitor SP600125 improves survivability and attenuates neuronal cell death in experimental cerebral malaria (ECM). (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/23455938

cerebral malaria

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author name string

Sripada Santosh Anand

1

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/23455938

Mulaka Maruthi

2

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/23455938

Phanithi Prakash Babu

3

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/23455938

publication date

28 February 2013

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/23455938

Parasitology Research

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/23455938

112

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/23455938

5

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/23455938

1959-1966

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/23455938

c-Jun N terminal kinases (JNK) are activated in the brain during the pathology of experimental cerebral malaria

1 reference

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21 January 2018

Cyclooxygenase-2 in the pathogenesis of murine cerebral malaria.

1 reference

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21 January 2018

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

1 reference

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21 January 2018

Induction of hepatitis by JNK-mediated expression of TNF-alpha

1 reference

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21 January 2018

Signal transduction by the JNK group of MAP kinases

1 reference

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21 January 2018

Cerebral malaria: the contribution of studies in animal models to our understanding of immunopathogenesis

1 reference

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21 January 2018

Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathway

1 reference

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21 January 2018

Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria

1 reference

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Neuroprotection against ischemic brain injury by SP600125 via suppressing the extrinsic and intrinsic pathways of apoptosis

1 reference

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21 January 2018

The c-Jun transcription factor--bipotential mediator of neuronal death, survival and regeneration

1 reference

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21 January 2018

JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease

1 reference

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21 January 2018

Pathogenesis, clinical features, and neurological outcome of cerebral malaria

1 reference

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21 January 2018

AP-1 function and regulation

1 reference

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21 January 2018

c-Jun kinase is a critical signaling molecule in a neonatal model of group B streptococcal sepsis

1 reference

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21 January 2018

The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase

1 reference

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21 January 2018

Role of JNK activation in apoptosis: a double-edged sword

1 reference

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21 January 2018

Increased c-fos expression in the brain during experimental murine cerebral malaria: possible association with neurologic complications

1 reference

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21 January 2018

Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1.

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3352-0

21 January 2018

Early activation of microglia in the pathogenesis of fatal murine cerebral malaria

1 reference

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21 January 2018

Role of c-Jun N-terminal kinase on lipopolysaccharide induced maturation of human monocyte-derived dendritic cells

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3352-0

21 January 2018

JNK inhibitor SP600125 reduces COX-2 expression by attenuating mRNA in activated murine J774 macrophages.

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3352-0

21 January 2018

Perforin mediated apoptosis of cerebral microvascular endothelial cells during experimental cerebral malaria

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3352-0

21 January 2018

Role of c-Jun concentration in neuronal cell death

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3352-0

21 January 2018

Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration

1 reference

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21 January 2018

Continuous c-fos expression precedes programmed cell death in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3352-0

21 January 2018

The global distribution of clinical episodes of Plasmodium falciparum malaria

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3352-0

21 January 2018

JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3352-0

21 January 2018

A new concept in neurodegeneration: TNFalpha is a silencer of survival signals

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3352-0

21 January 2018

Genetic susceptibility to systemic lupus erythematosus protects against cerebral malaria in mice

1 reference

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21 January 2018

SP600125, a new JNK inhibitor, protects dopaminergic neurons in the MPTP model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3352-0

21 January 2018

JNK inhibitor protects dopaminergic neurons by reducing COX-2 expression in the MPTP mouse model of subacute Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3352-0

21 January 2018

Protein kinases of the human malaria parasite Plasmodium falciparum: the kinome of a divergent eukaryote

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3352-0

21 January 2018

Neuronal apoptosis, metallothionein expression and proinflammatory responses during cerebral malaria in mice

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3352-0

21 January 2018

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3352-0

21 January 2018

Role of c-Jun N-terminal kinase in early brain injury after subarachnoid hemorrhage.

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3352-0

21 January 2018

Vinblastine-induced phosphorylation of Bcl-2 and Bcl-XL is mediated by JNK and occurs in parallel with inactivation of the Raf-1/MEK/ERK cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/23455938

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of Jun transcription factor expression and phosphorylation in neuronal differentiation, neuronal cell death, and plastic adaptations in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23455938

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of cell death-associated phospho-c-Jun and p53-activated gene 608 in hippocampal CA1 neurons following global ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23455938

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An ultrastructural study of the brain in fatal Plasmodium falciparum malaria

1 reference

https://pubmed.ncbi.nlm.nih.gov/23455938

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The regulation of the human tumor necrosis factor alpha promoter region in macrophage, T cell, and B cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/23455938

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in experimental cerebral malaria: spatial profile of cleaved caspase-3 and ultrastructural alterations in different disease stages

1 reference

https://pubmed.ncbi.nlm.nih.gov/23455938

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00436-013-3352-0

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/23455938

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/23455938

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