(Q45964666)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536068%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536068%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536068%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

author name string

M V Tzvetkov

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536068%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

S V Vormfelde

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536068%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

D Balen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536068%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

I Meineke

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536068%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

D Sehrt

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536068%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

I Sabolić

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536068%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

H Koepsell

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536068%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

J Brockmöller

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536068%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

language of work or name

English

0 references

publication date

17 June 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536068%20AND%20SRC:MED&resulttype=core&format=json

Clinical Pharmacology & Therapeutics

31 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536068%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

volume

86

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536068%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

page(s)

299-306

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536068%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536068%20AND%20SRC:MED&resulttype=core&format=json

Transporters and drug therapy: implications for drug disposition and disease

31 January 2020

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Torsemide renal clearance and genetic variation in luminal and basolateral organic anion transporters

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The polymorphisms Asn130Asp and Val174Ala in OATP1B1 and the CYP2C9 allele *3 independently affect torsemide pharmacokinetics and pharmacodynamics.

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Pharmacokinetics of metformin after intravenous and oral administration to man

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Clinical pharmacokinetics of metformin

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7 January 2021

Involvement of organic cation transporter 1 in the lactic acidosis caused by metformin

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Estimating the contribution of genes and environment to variation in renal drug clearance

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Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.

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Metformin transport by renal basolateral organic cation transporter hOCT2.

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Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action

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7 January 2021

Identification and functional characterization of genetic variants of human organic cation transporters in a Korean population

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7 January 2021

Identification of genetic variations of the human organic cation transporter hOCT1 and their functional consequences

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7 January 2021

Genetic variability of the extraneuronal monoamine transporter EMT (SLC22A3).

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7 January 2021

Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function

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7 January 2021

Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions

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7 January 2021

Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1

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7 January 2021

Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics

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7 January 2021

Genetic variants of the organic cation transporter 2 influence the disposition of metformin

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7 January 2021

OCT2 polymorphisms and in-vivo renal functional consequence: studies with metformin and cimetidine

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7 January 2021

Genetic variation in the multidrug and toxin extrusion 1 transporter protein influences the glucose-lowering effect of metformin in patients with diabetes: a preliminary study

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7 January 2021

Functional variants of OCTN cation transporter genes are associated with Crohn disease

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7 January 2021

Effects of genetic variation in the novel organic cation transporter, OCTN1, on the renal clearance of gabapentin

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Cloning and functional expression of a human liver organic cation transporter

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7 January 2021

Vectorial transport of the plant alkaloid berberine by double-transfected cells expressing the human organic cation transporter 1 (OCT1, SLC22A1) and the efflux pump MDR1 P-glycoprotein (ABCB1).

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7 January 2021

Pax transactivation-domain interacting protein is required for urine concentration and osmotolerance in collecting duct epithelia.

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7 January 2021

Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin

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7 January 2021

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7 January 2021

Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta.

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7 January 2021

Natural allelic variants of breast cancer resistance protein (BCRP) and their relationship to BCRP expression in human intestine.

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7 January 2021

Individual PKC-phosphorylation sites in organic cation transporter 1 determine substrate selectivity and transport regulation

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7 January 2021

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7 January 2021

Measurement of the renal clearance of drugs

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7 January 2021

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7 January 2021

Human organic cation transporter (OCT1 and OCT2) gene polymorphisms and therapeutic effects of metformin.

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7 January 2021

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7 January 2021

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7 January 2021

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