(Q46021227)

18 December 2017

title

PDK1 signaling in oocytes controls reproductive aging and lifespan by manipulating the survival of primordial follicles. (English)

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18 December 2017

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Wenjing Zheng

4

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Pradeep Reddy

object named as

Pradeep Reddy

1

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Sinisa Volarevic

object named as

Sinisa Volarevic

10

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Ilpo Huhtaniemi

11

object named as

Ilpo Huhtaniemi

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18 December 2017

author name string

Deepak Adhikari

2

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18 December 2017

Deepak Adhikari

3

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18 December 2017

Shawn Liang

5

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18 December 2017

Tuula Hämäläinen

6

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18 December 2017

Virpi Tohonen

7

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18 December 2017

Wataru Ogawa

8

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18 December 2017

Tetsuo Noda

9

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18 December 2017

Kui Liu

12

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18 December 2017

publication date

7 May 2009

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18 December 2017

published in

Human Molecular Genetics

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18 December 2017

volume

18

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18 December 2017

issue

15

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18 December 2017

page(s)

2813-2824

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18 December 2017

Female reproductive ageing: current knowledge and future trends

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP217

A new model of reproductive aging: the decline in ovarian non-growing follicle number from birth to menopause

21 January 2018

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A model conforming the decline in follicle numbers to the age of menopause in women.

21 January 2018

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Oocyte apoptosis: like sand through an hourglass

21 January 2018

1 reference

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Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool.

21 January 2018

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The phosphoinositide 3-kinase pathway

21 January 2018

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The phosphoinositide 3-kinase pathway and cancer

21 January 2018

1 reference

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21 January 2018

Expanding mTOR signaling

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP217

PDK1, the master regulator of AGC kinase signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP217

The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

21 January 2018

1 reference

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Essential role of PDK1 in regulating cell size and development in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP217

Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP217

Deficiency of PDK1 in liver results in glucose intolerance, impairment of insulin-regulated gene expression and liver failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP217

Restoration of glucokinase expression in the liver normalizes postprandial glucose disposal in mice with hepatic deficiency of PDK1.

21 January 2018

1 reference

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The serine kinase phosphoinositide-dependent kinase 1 (PDK1) regulates T cell development

21 January 2018

1 reference

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Role of hepatic STAT3 in brain-insulin action on hepatic glucose production

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP217

Differential oocyte-specific expression of Cre recombinase activity in GDF-9-iCre, Zp3cre, and Msx2Cre transgenic mice.

21 January 2018

1 reference

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Mouse ovarian germ cell cysts undergo programmed breakdown to form primordial follicles.

21 January 2018

1 reference

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Intercellular communication in the mammalian ovary: oocytes carry the conversation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP217

Activation of Akt (PKB) and suppression of FKHRL1 in mouse and rat oocytes by stem cell factor during follicular activation and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP217

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

1 reference

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

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Infertility caused by retardation of follicular development in mice with oocyte-specific expression of Foxo3a.

21 January 2018

1 reference

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An encore for ribosome biogenesis in the control of cell proliferation

21 January 2018

1 reference

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Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6

21 January 2018

1 reference

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Prolongation of ovarian lifespan into advanced chronological age by Bax-deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP217

Evidence of apoptosis in human primordial and primary follicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP217

Ultrastructural evaluation of oocytes during atresia in rat ovarian follicles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP217

DNA strand breaks and phosphatidylserine redistribution in newly ovulated and cultured mouse and human oocytes: occurrence and relationship to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP217

Prepubertal primordial follicle loss in mice is not due to classical apoptotic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP217

Germline stem cells and follicular renewal in the postnatal mammalian ovary

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP217

21 January 2018

Identifiers

DOI

10.1093/HMG/DDP217

1 reference

18 December 2017

1 reference

18 December 2017