(Q46071912)

19 December 2017

title

Allosteric inhibition of VIM metallo-β-lactamases by a camelid nanobody (English)

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19 December 2017

author

Jan Steyaert

8

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19 December 2017

Els Pardon

Els Pardon

4

1 reference

ORCID Public Data File 2021

Vasundara Srinivasan

5

Vasundara Srinivasan

1 reference

19 December 2017

Ulrich Wernery

6

Ulrich Wernery

1 reference

19 December 2017

Andy Chevigné

3

Andy Chevigné

1 reference

19 December 2017

author name string

Jean S Sohier

1

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19 December 2017

Clémentine Laurent

2

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19 December 2017

Patricia Lassaux

7

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19 December 2017

Moreno Galleni

9

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19 December 2017

language of work or name

English

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publication date

1 March 2013

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19 December 2017

number of pages

10

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based on heuristic

inferred from page(s)

published in

Biochemical Journal

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19 December 2017

volume

450

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19 December 2017

issue

3

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19 December 2017

page(s)

477-486

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19 December 2017

The structure of β-lactamases

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121305

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21 January 2018

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Metallo-beta-lactamases (classification, activity, genetic organization, structure, zinc coordination) and their superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121305

Update of the standard numbering scheme for class B beta-lactamases

21 January 2018

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Metallo-β-lactamases: a last frontier for β-lactams?

21 January 2018

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Metallo-beta-lactamases: the quiet before the storm?

21 January 2018

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Epidemiological expansion, structural studies, and clinical challenges of new β-lactamases from gram-negative bacteria.

21 January 2018

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Evidence of adaptability in metal coordination geometry and active-site loop conformation among B1 metallo-beta-lactamases

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20121305

Current challenges in antimicrobial chemotherapy: focus on ß-lactamase inhibition

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20121305

Three decades of beta-lactamase inhibitors

21 January 2018

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Beta-lactamase inhibitors: the story so far.

21 January 2018

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Beta-lactamase inhibitors derived from single-domain antibody fragments elicited in the camelidae

21 January 2018

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Recognition of antigens by single-domain antibody fragments: the superfluous luxury of paired domains

21 January 2018

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Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20121305

Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology

21 January 2018

1 reference

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Potent enzyme inhibitors derived from dromedary heavy-chain antibodies

21 January 2018

1 reference

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Camel single-domain antibody inhibits enzyme by mimicking carbohydrate substrate

21 January 2018

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Substrate-dependent modulation of enzyme activity by allosteric effector antibodies

21 January 2018

1 reference

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Constraining enzyme conformational change by an antibody leads to hyperbolic inhibition

21 January 2018

1 reference

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Hospital outbreak of multiple clones of Pseudomonas aeruginosa carrying the unrelated metallo-beta-lactamase gene variants blaVIM-2 and blaVIM-4

21 January 2018

1 reference

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Protein production by auto-induction in high density shaking cultures

21 January 2018

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Biochemical and Structural Characterization of the Subclass B1 Metallo- -Lactamase VIM-4

21 January 2018

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Selection and identification of single domain antibody fragments from camel heavy-chain antibodies

21 January 2018

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Camelid immunoglobulins and nanobody technology.

21 January 2018

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A novel metallo-beta-lactamase, Mbl1b, produced by the environmental bacterium Caulobacter crescentus

21 January 2018

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Impact of remote mutations on metallo-beta-lactamase substrate specificity: implications for the evolution of antibiotic resistance

21 January 2018

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Allostery: an illustrated definition for the 'second secret of life'.

21 January 2018

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The role of dynamics in allosteric regulation

21 January 2018

1 reference

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A metallo-beta-lactamase enzyme in action: crystal structures of the monozinc carbapenemase CphA and its complex with biapenem

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121305

Antibiotic recognition by binuclear metallo-beta-lactamases revealed by X-ray crystallography

21 January 2018

1 reference

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Trapping and characterization of a reaction intermediate in carbapenem hydrolysis by B. cereus metallo-beta-lactamase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121305

On the mechanism of the metallo-beta-lactamase from Bacteroides fragilis

21 January 2018

1 reference

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Hydroxyl groups in the betabeta sandwich of metallo-beta-lactamases favor enzyme activity: Tyr218 and Ser262 pull down the lid.

21 January 2018

1 reference

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Mimicking natural evolution in metallo-beta-lactamases through second-shell ligand mutations

21 January 2018

1 reference

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Adaptive protein evolution grants organismal fitness by improving catalysis and flexibility

21 January 2018

1 reference

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Role of a solvent-exposed tryptophan in the recognition and binding of antibiotic substrates for a metallo-beta-lactamase

21 January 2018

1 reference

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NMR characterization of the metallo-beta-lactamase from Bacteroides fragilis and its interaction with a tight-binding inhibitor: role of an active-site loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121305

Site-selective binding of Zn(II) to metallo-beta-lactamase L1 from Stenotrophomonas maltophilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121305

Motion of the zinc ions in catalysis by a dizinc metallo-beta-lactamase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121305

The crystal structure of the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia at 1.7 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121305

Crystal structure of NDM-1 reveals a common β-lactam hydrolysis mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121305

Crystal structure of New Delhi metallo-β-lactamase reveals molecular basis for antibiotic resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121305

Molecular dynamic simulations of the metallo-beta-lactamase from Bacteroides fragilis in the presence and absence of a tight-binding inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121305

In vitro antiviral activity of single domain antibody fragments against poliovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121305

21 January 2018

Identifiers

DOI

10.1042/BJ20121305

1 reference

19 December 2017

1 reference

19 December 2017