(Q46196856)

20 December 2017

review article

1 reference

title

Systems genetics analysis of cancer susceptibility: from mouse models to humans (English)

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20 December 2017

author name string

David Quigley

series ordinal

1

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20 December 2017

Allan Balmain

series ordinal

2

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20 December 2017

publication date

28 July 2009

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20 December 2017

published in

Nature Reviews Genetics

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20 December 2017

volume

10

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20 December 2017

issue

9

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20 December 2017

page(s)

651-657

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20 December 2017

Identification of PATCHED mutations in medulloblastomas by direct sequencing

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Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice

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Multiple loci with different cancer specificities within the 8q24 gene desert

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Taking stock of complex trait genetics in mice

31 March 2020

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Rat Mcs5a is a compound quantitative trait locus with orthologous human loci that associate with breast cancer risk

31 March 2020

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The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia

31 March 2020

1 reference

The Mom1AKR intestinal tumor resistance region consists of Pla2g2a and a locus distal to D4Mit64

31 March 2020

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Cancer as a complex genetic trait: tumor susceptibility in humans and mouse models

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Common and rare variants in multifactorial susceptibility to common diseases

31 March 2020

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Cancer susceptibility in the mouse: genetics, biology and implications for human cancer

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Genetic dissection of transcriptional regulation in budding yeast

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Genetics of gene expression surveyed in maize, mouse and man

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Genetic analysis of genome-wide variation in human gene expression

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Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function

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Genetic architecture of mouse skin inflammation and tumour susceptibility

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Distinct genetic loci control development of benign and malignant skin tumours in mice.

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Genetic mapping of a pulmonary adenoma resistance locus (Par1) in mouse

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A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice

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Sipa1 is a candidate for underlying the metastasis efficiency modifier locus Mtes1.

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Lgr5 marks cycling, yet long-lived, hair follicle stem cells.

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Identification of stem cells in small intestine and colon by marker gene Lgr5

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Vitamin D status and cancer incidence and mortality

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Vitamin D(3) receptor ablation sensitizes skin to chemically induced tumorigenesis

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An integrative genomics approach to infer causal associations between gene expression and disease

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Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks

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Genetic interactions between transcription factors cause natural variation in yeast

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Effect of ablation or inhibition of stromal matrix metalloproteinase-9 on lung metastasis in a breast cancer model is dependent on genetic background

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Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer

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Pharmacogenetics in breast cancer therapy

31 March 2020

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Thematic review series: systems biology approaches to metabolic and cardiovascular disorders. Reverse engineering gene networks to identify key drivers of complex disease phenotypes

31 March 2020

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Theory and limitations of genetic network inference from microarray data

31 March 2020

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Extracting gene networks for low-dose radiation using graph theoretical algorithms

31 March 2020

1 reference

Allele-specific Hras mutations and genetic alterations at tumor susceptibility loci in skin carcinomas from interspecific hybrid mice.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19636343

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mutations of the PATCHED gene in several types of sporadic extracutaneous tumors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19636343

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRG2617

1 reference

20 December 2017

1 reference

20 December 2017